250 Results for "

complex II

" in MedChemExpress (MCE) Product Catalog:
Products (250)

250 Results for "complex II" in MCE Product Catalog:

Cat. No.: HY-P4666
CAS No.: 13589-07-6
Research Areas:  

Others

Valylhistidine is a dipeptide composed of valine and histidine (Val-His). Valylhistidine can form a dipeptide complex with Cu (II) that mimics superoxide dismutase but lacks activity .
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Cat. No.: HY-N2306A
CAS No.: 75443-99-1
Synonyms: Aclarubicin hydrochloride
Aclacinomycin A (Aclarubicin) hydrochloride is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A hydrochloride is an inhibitor of topoisomerase I and II. Aclacinomycin A hydrochloride inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A hydrochloride might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .
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Cat. No.: HY-115853
CAS No.: 78668-34-5
Research Areas:  

Others

Pyclen forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI .
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Cat. No.: HY-19882
CAS No.: 941285-15-0
Research Areas:  

Infection

BAL-30072 is a siderophore-bearing monocyclic β-lactam antibiotic with antibacterial activity. BAL-30072 inhibits penicillin-binding proteins 1a, 1b, and 3, thereby disrupting bacterial cell wall synthesis. BAL-30072 inhibits mitochondrial electron transport chain complex II and complex III, while also inhibiting glycolysis and mitochondrial fatty acid β-oxidation. BAL-30072 induces mitochondrial ROS production, cellular ATP depletion, reduces mitochondrial membrane potential, and triggers hepatocyte apoptosis via caspase-3/7 activation. BAL-30072 is a substrate of the hepatic uptake transporters OAT1 and OAT3. BAL-30072 can be used in research related to bacterial infections .
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Cat. No.: HY-W013066
CAS No.: 205319-10-4
Pd(Xantphos)Cl2 is a palladium(II) complex catalyst that can be used in organic synthesis research.
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Cat. No.: HY-P4531
CAS No.: 21435-27-8
Research Areas:  

Neurological Disease

H-Ser-Tyr-OH is a dipeptide. H-Ser-Tyr-OH can form a copper(II) complex .
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Cat. No.: HY-P1826
CAS No.: 648881-58-7
Target:  

CD74

Research Areas:  

Inflammation/Immunology Cancer

CLIP (86-100) is amino acids 86 to 100 fragment of class II-associated invariant chain peptide (CLIP). CLIP is a small self-peptide and cleavage product of the invariant chain that resides in the HLA-II antigen binding groove and is believed to play a critical role in the assembly and transport of MHC class II alphabetaIi complexes through its interaction with the class II peptide-binding site .
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Cat. No.: HY-DY1017
CAS No.: 11078-21-0
Filipin complex (solution) is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718) , 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm) .
Solvent and concentration: DMSO: 5 mg/mL
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Cat. No.: HY-W010380
CAS No.: 3878-55-5
Methyl succinate is a mitochondrial complex II substrate. Methyl succinate can bypass the inhibition of complex I by Metformin (HY-B0627), restore mitochondrial electron transfer, and reduce AMPK phosphorylation. Methyl succinate is capable of protecting MIN6 β-cells and primary rat β-cells from biguanide-induced toxicity and apoptosis in vitro. Methyl succinate can be used in the research of diseases such as diabetes mellitus .
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Cat. No.: HY-W010854
CAS No.: 72003-83-9
Synonyms: dADP disodium
2'-Deoxyadenosine 5'-diphosphate disodium (dADP disodium) is an inhibitor of Polynucleotide phosphorylase and Polyadenylate polymerase. 2'-Deoxyadenosine 5'-diphosphate disodium inhibits polyadenylate synthesis in permeabilized bacterial cells. As a chelating agent, 2'-Deoxyadenosine 5'-diphosphate disodium forms 1:1 complexes with trivalent lanthanides, Manganese (II) and Copper (II) ions, with unique coordination modes and structural conformations for each ion type .
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Cat. No.: HY-W033277
CAS No.: 21797-13-7
Synonyms: NSC 307191; Palladium(II) tetrafluoroborate tetraacetonitrile complex
Research Areas:  

Others

Tetrakis(acetonitrile)palladium(II) tetrafluoroborate (NSC 307191) acts as a potent Lewis acid and facilitates the formation of the 2:1 complex [Pd(1,2-bis(2′-pyridylethynyl)benzene)2](BF4)2 through the Sonogashira cross-coupling reaction.
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Cat. No.: HY-W033466
CAS No.: 37366-09-9
Synonyms: Benzeneruthenium(II) chloride dimer
Benzeneruthenium(II) Chloride Dimer (Benzeneruthenium(II) chloride dimer) is a dinuclear complex. Benzeneruthenium(II) Chloride Dimer undergoes a hydrolysis reaction to generate a mixture of mononuclear ruthenium complexes in equilibrium .
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Cat. No.: HY-W020952
CAS No.: 14024-61-4
Synonyms: Palladium(Ⅱ) 2,4-pentanedionate; Pd(acac)2
Palladium(II) acetylacetonate is a metal-organic complex. Palladium(II) acetylacetonate upregulates the expression of GRP78, ATF-4, XBP-1, CHOP, and phosphorylated c-Jun. Palladium(II) acetylacetonate induces Apoptosis. Palladium(II) acetylacetonate has anticancer effects against non-small cell lung cancer, gastric cancer, leukemia, and cervical cancer .
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Cat. No.: HY-Y1102A
CAS No.: 142-71-2
Copper(II) acetate, 99.99% trace metals basis is a dinuclear metal complex that can be used a source of copper and oxidizing agent in inorganic synthesis, and as a catalyst in organic synthesis .
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Cat. No.: HY-W243460
CAS No.: 39208-15-6
Research Areas:  

Others

EDTA copper (II) disodium salt, 97% is a negatively charged copper (II)-ethylenediaminetetraacetic acid chelate and also an adsorption substrate. EDTA copper (II) disodium salt, 97% forms amide bonds with chitosan amino groups in weakly acidic (pH 3-5) solutions, while it forms the CuEDTA (OH) 3− hydroxyl complex in strongly alkaline (pH > 12) solutions. EDTA copper (II) disodium salt, 97% can be adsorbed onto granular activated carbon, with electrostatic interactions dominating its pH-dependent adsorption behavior. EDTA copper (II) disodium salt, 97% can be used to eliminate the inhibition of enzyme-catalyzed reactions caused by trace heavy metals .
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Cat. No.: HY-146693
CAS No.: 1807631-83-9
Purity:  99.36%
Target:  

TGF-β Receptor

Research Areas:  

Cancer

CJJ300 is a transforming growth factor-β (TGF-β) inhibitor with an IC50 of 5.3 µM. CJJ300 inhibits TGF-β signaling by disrupting the formation of the TGF-β-TβR-I-TβR-II signaling complex .
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Cat. No.: HY-P5412
CAS No.: 331941-87-8
Synonyms: Listeriolysin O 190 peptide
Target:  

Inhibitory Antibodies

Research Areas:  

Others

LLO (190-201) (Listeriolysin O 190 peptide) is a biological active peptide. (This peptide is a major histocompatibility complex class II (MHC-II)-restricted peptide, LLO190 (NEKYAQAYPNVS), from the listeriolysin O protein of Listeria monocytogenes, which generates an LLO190-specific Th response. This peptide subsequently challenge recombinant L. monocytogenes expressing the MHC-I-restricted epitope of ovalbumin (Ova257, SIINFEKL).)
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Cat. No.: HY-139813
CAS No.: 1416900-51-0
Purity:  ≥95.0%
Research Areas:  

Cancer

Phenanthriplatin is a monovalent platinum(II)-based complex with a large cytotoxicity against cancer cells .
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Cat. No.: HY-142956
Purity:  99.65%
Research Areas:  

Cancer

ROS-ERS inducer 1 is a type II ICD (immunogenic cell death) inducer. ROS-ERS inducer 1 is a Pt(II)-N-heterocyclic carbene (Pt(II)-NHC) complex derived from 4,5-diarylimidazole. ROS-ERS inducer 1 successfully induces endoplasmic reticulum stress (ERS) accompanied by reactive oxygen species (ROS) generation and finally lead to the release of damage-associated molecular patterns (DAMPs) in HCC cells. ROS-ERS inducer 1 displays much higher anticancer activities than Cisplatin .
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Cat. No.: HY-157335
CAS No.: 120066-53-7
Purity:  ≥70.0%
Research Areas:  

Others

Mn(II)-DO3A sodium is a Mn(II) complex and a potential alternative to Gd-based MRI contrast agents .
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