239 Results for "

neutralization

" in MedChemExpress (MCE) Product Catalog:
Products (239)

239 Results for "neutralization" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99134

Target:  

c-Fms

Anti-Mouse GM-CSF Antibody (MP1-22E9) is a rat-derived anti-mouse GM-CSF IgG2a antibody inhibitor. Anti-Mouse GM-CSF Antibody (MP1-22E9) can neutralize GM-CSF. Anti-Mouse GM-CSF Antibody (MP1-22E9) can be used for the researches of cancer, infection inflammation and immunology, such as cholangiocarcinoma and arthritis .
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1 Cited Publications
Cat. No.: HY-P990220
Anti-Mouse IL-18 Antibody (YIGIF74-1G7) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-18. Anti-Mouse IL-18 Antibody (YIGIF74-1G7) can neutralize IL-18. Anti-Mouse IL-18 Antibody (YIGIF74-1G7) can be used for the researches of cancer, infection, inflammation and immunology, such as hepatocellular carcinoma and eosinophilic esophagitis .
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1
1 Cited Publications
Cat. No.: HY-Y0756
CAS No.: 144-55-8
Synonyms: Sodium hydrogen carbonate
Target:  

Bacterial

Research Areas:  

Infection Cancer

Sodium bicarbonate (Sodium hydrogen carbonate; Soda bicarbonate) is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .
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1
1 Cited Publications
Cat. No.: HY-P99590A
Synonyms: RAP-011
Sotatercept (mIgG2a) (RAP-011), the murine homolog of Sotatercept (ACE-011) (HY-P99590), is a soluble activin receptor type IIA (ActRIIA) ligand trap. Sotatercept (mIgG2a) inhibits the binding of activin A and other members of the TGF-β superfamily (such as Activin A/B, GDF11 and BMP9/10) to their receptors by combining and neutralizing them, thereby regulating cell proliferation and differentiation. Sotatercept (mIgG2a) mainly inhibits the SMAD2/3 signaling pathway, and can be used in various diseases such as chronic kidney disease. Sotatercept (mIgG2a) reduces the expression of erythropoietic hepcidin (ERFE), regulates iron metabolism, and promotes red blood cell production. Sotatercept (mIgG2a) has a dual effect of promoting bone formation (anabolic) and inhibiting bone resorption (catabolic) .
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Cat. No.: HY-P99486
CAS No.: 339308-60-0
Synonyms: ABT-874

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody. Briakinumab targets and neutralizes IL-12 and IL-23. Briakinumab can be used for the research of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis .
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Cat. No.: HY-P9945
CAS No.: 196078-29-2
Synonyms: SB 240563
Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .
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Cat. No.: HY-P9945A
CAS No.: 196078-29-2

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Mepolizumab (anti-IL5) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .
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Cat. No.: HY-P99192
CAS No.: 1365287-97-3
Synonyms: LY2875358

Target:  

c-Met/HGFR

Research Areas:  

Cancer

Emibetuzumab (LY2875358) is a humanized bivalent MET antibody (IgG4 type). Emibetuzumab shows high neutralization and internalization activities, resulting in inhibition of both HGF-dependent and HGF-independent MET pathway activation and tumor growth. Emibetuzumab can be used in study of cancer .
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Cat. No.: HY-P99564
CAS No.: 2417213-72-8
Synonyms: 3BNC117-LS; GS-5423

Target:  

HIV

Research Areas:  

Infection Inflammation/Immunology

Teropavimab (3BNC117-LS) is a broadly neutralizing antibody targeting the CD4-binding site of the HIV-1 envelope. Teropavimab binds to the CD4-binding site of HIV-1 gp120 to neutralize viruses, including multidrug-resistant HIV-1. Teropavimab can be used in studies related to HIV-1 infection and multidrug-resistant HIV-1 infection .
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Cat. No.: HY-P99947
CAS No.: 2540797-21-3
Synonyms: XVR011

Target:  

SARS-CoV

Research Areas:  

Infection

Rimteravimab (XVR011) is a bivalent VHH-Fc antibody with potent neutralizing activity with high stability, broad coverage and silenced Fc effector functions against the disease caused by SARS-CoV-2 .
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Cat. No.: HY-P991069
CAS No.: 1412901-55-3

Target:  

HIV

Research Areas:  

Infection

VRC-01 is a broadly neutralizing IgG1 monoclonal antibody that targets HIV-1 envelope glycoprotein gp120 Protein. VRC-01 blocks HIV-1 viral entry by mimicking CD4 receptor interaction with HIV-1 gp120 and neutralizes broad HIV-1 clades. VRC-01 can be used for the research of HIV-1 infection .
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Cat. No.: HY-P990036
CAS No.: 2639474-65-8
Synonyms: PF-06823859

Target:  

IFNAR

Research Areas:  

Inflammation/Immunology

Dazukibart (PF-06823859) is a potent, selective humanized IgG1 neutralizing monoclonal antibody that targets interferon β (IFNβ). Dazukibart can be used in the study of moderate to severe dermatomyositis .
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Cat. No.: HY-P99375
CAS No.: 1188275-92-4
Synonyms: IMC-RON8; LY3012219; Anti-MSPR/RON/CD136 Reference Antibody (narnatumab)

Target:  

Tyrosinase c-Met/HGFR

Research Areas:  

Cancer

Narnatumab (IMC-RON8) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP), with a Kd of 32 pM. Narnatumab can be used for the research of cancer .
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Cat. No.: HY-P99424
CAS No.: 1589503-30-9
Synonyms: RG 7624; RO 5553110; NI-1401

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities .
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Cat. No.: HY-P99213
CAS No.: 1310680-64-8
Synonyms: GSK1223249
Ozanezumab (GSK1223249) is a humanized, Fc-inactivated monoclonal antibody that targets the nervous system protein Nogo-A. Ozanezumab promotes neurite outgrowth and axonal regeneration by neutralizing Nogo-A signaling. Ozanezumab is used for research on neurodegenerative diseases such as amyotrophic lateral sclerosis and multiple sclerosis [1] .
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Cat. No.: HY-P99556
CAS No.: 2420564-02-7
Synonyms: AZD8895; COV2-2196

Target:  

SARS-CoV

Research Areas:  

Infection

Tixagevimab (AZD8895) is a human monoclonal antibody that targets the SARS-CoV-2 receptor binding domain (RBD). It exhibits neutralizing activity against SARS-CoV-2 by binding to the RBD and the S-glycoprotein ectodomain and blocking S-glycoprotein-mediated binding to the receptor .
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Cat. No.: HY-P99621
CAS No.: 2467411-25-0
Synonyms: NPC-21; EV2038

Target:  

CMV

Research Areas:  

Infection

Fiztasovimab (NPC-21; EV2038) is a fully human IgG1λ mAb against human cytomegalovirus (hCMV). Fiztasovimab acts neutralizing activity by binding to the antigenic domain 1 of glycoprotein B on hCMV envelope. Fiztasovimab inhibits cell-to-cell transmission of hCMV .
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Cat. No.: HY-P99368
CAS No.: 1831128-32-5
Synonyms: MCS110

Target:  

c-Fms

Research Areas:  

Metabolic Disease Cancer

Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis .
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Cat. No.: HY-125457
CAS No.: 145-50-6
Synonyms: p-Naphtolbenzein
α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein is commonly used in experiments such as acid-base neutralization reactions, titration, and pH measurement .
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Cat. No.: HY-P99900
CAS No.: 138660-96-5
Synonyms: MSL-109

Target:  

CMV

Research Areas:  

Infection

Sevirumab (MSL-109) is a human IgG1 neutralizing monoclonal antibody against cytomegalovirus (CMV). Sevirumab recognizes CMV gH complexes and inhibits CMV replication with an EC50 of 0.3 μg/mL .
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