Teropavimab
Based on 1 Customer Validation
Teropavimab (3BNC117-LS) is a neutralizing antibody against HIV-1. Teropavimab can be used for the research of HIV infection.
For research use only. We do not sell to patients.
- Purity: 99.70%
- CAS No.: 2417213-72-8
- Molecular Weight:145.889 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human IgG1 kappa
Human
gp120/Glycoprotein 120
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Human IgG1 kappa
ELISA, FACS, Functional assay
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Immobilized Envelope glycoprotein gp120 Protein, HIV-1 (AAC31819, HEK293, His, HY-P76390) can bind Teropavimab. The EC50 for this effect is 196.4 ng/mL.
Chemical Information
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CAS No. 2417213-72-8
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Appearance Liquid
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Molecular Weight 145.889 kDa
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Color Colorless to light yellow
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SMILES
[Teropavimab]
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Synonyms
3BNC117-LS; GS-5423
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (256 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Julio C C Lorenzi, et al. Neutralizing Activity of Broadly Neutralizing anti-HIV-1 Antibodies against Primary African Isolates. J Virol. 2020 Dec 9;95(5):e01909-20. [Content Brief]
[2]. Gautam R, et al. A single injection of crystallizable fragment domain-modified antibodies elicits durable protection from SHIV infection. Nat Med. 2018 May;24(5):610-616. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)