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Afasevikumab

(Synonyms: RG 7624; RO 5553110; NI-1401)
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Based on 1 Customer Validation

Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities.

For research use only. We do not sell to patients.

  • Purity: 95%
  • CAS No.: 1589503-30-9
  • Molecular Weight:146.065 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Afasevikumab
  • Experimental Validation Results for Afasevikumab
  • Experimental Validation Results for Afasevikumab
  • Afasevikumab Chemical Structure
    Afasevikumab Chemical Structure
CAS No.: 1589503-30-9
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Afasevikumab on AHC2 biosensor, can bind IL-17A Protein, Human (HEK293, His, HY-P70527) with an affinity constant of <1.000E-11 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Afasevikumab (HY-P99424, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Afasevikumab Chemical Structure
    1/16
  • Afasevikumab
  • Loaded Afasevikumab on AHC2 biosensor, can bind IL-17A Protein, Human (HEK293, His, HY-P70527) with an affinity constant of <1.000E-11 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 Jurkat cells with Afasevikumab (HY-P99424, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).