616 Results for "

platelet aggregation,

" in MedChemExpress (MCE) Product Catalog:
Products (616)

616 Results for "platelet aggregation," in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-Y0882
CAS No.: 5470-11-1
Target:  

Monoamine Oxidase

Research Areas:  

Cardiovascular Disease

Hydroxylamine hydrochloride is a selective Monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of nitrogen cycle in aerobic ammonium oxidizers microorganisms, such as ammonium oxidizing bacteria (AOB), ammonium oxidizing archaea (AOA) and complete ammonium oxidizing bacteria (comammox). Hydroxylamine hydrochloride impacts NO and N2O emissions by aerobic ammonium oxidizers microorganisms and inhibits nitrite oxidizing bacteria (NOB) activity .
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2
2 Cited Publications
Cat. No.: HY-101308A
Purity:  99.6%
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

MRS2179 tetrasodium hydrate is a competitive P2Y1 receptor antagonist, with a Kb of 102 nM and a pA2 of 6.99 for turkey P2Y1 receptor. MRS2179 tetrasodium hydrate is selective for P2Y1 over P2X1 (IC50=1.15 µM), P2X3 (12.9 µM), P2X2, P2X4, P2Y2, P2Y4, and P2Y6 receptors . MRS2179 tetrasodium hydrate inhibits platelet aggregation .
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2
2 Cited Publications
Cat. No.: HY-N0353
CAS No.: 13657-68-6
Synonyms: (+)-Curdione
Curdione ((+)-Curdione) is an orally active sesquiterpenoid. Curdione inhibits platelet aggregation. Curdione induces ferroptosis in colorectal cancer via m6A methylation mediated by METTL14 and YTHDF2. Curdione inhibits ferroptosis in Isoproterenol (HY-B0468)-induced myocardial infarction by regulating the Keap1/Trx1/GPX4 signaling pathway, suppressing oxidative stress (ROS) and apoptosis. Curdione ameliorates Doxorubicin (HY-15142)-induced cardiotoxicity by inhibiting oxidative stress (ROS) and activating the Nrf2/HO-1 pathway. Curdione ameliorates sepsis-induced lung injury by inhibiting platelet-mediated neutrophil extracellular trap formation. Curdione ameliorates Bleomycin (HY-17565A)-induced pulmonary fibrosis by inhibiting TGF-β-induced fibroblast-to-myofibroblast differentiation. Curdione exhibits neuroprotective effects against focal cerebral ischemia-reperfusion injury in rats. Curdione exerts antiproliferative effects against human uterine leiomyosarcoma by targeting IDO1. Curdione protects vascular endothelial cells and atherosclerosis by regulating DNMT1-mediated ERBB4 promoter methylation. Curdione inhibits inducible prostaglandin E2 production (IC50 = 1.1 μM) and cyclooxygenase 2 expression .
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1
1 Cited Publications
Cat. No.: HY-15284
CAS No.: 150322-43-3
Purity:  99.75%
Synonyms: PCR 4099
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .
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1
1 Cited Publications
Cat. No.: HY-15284A
CAS No.: 389574-19-0
Purity:  98.49%
Synonyms: PCR 4099 hydrochloride
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .
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1
1 Cited Publications
Cat. No.: HY-101054
CAS No.: 130089-98-4
Purity:  98.98%
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

NQ301 is an antithrombotic agent; inhibits collagen-challenged rabbit platelet aggregation with an IC50 of 10 mg/mL.
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1
1 Cited Publications
Cat. No.: HY-P1741
CAS No.: 137235-80-4
Research Areas:  

Cardiovascular Disease

Fibrinogen-Binding Peptide is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide can be used for research on thrombosis .
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1
1 Cited Publications
Cat. No.: HY-134216
CAS No.: 146724-86-9
MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP .
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1
1 Cited Publications
Cat. No.: HY-112322
CAS No.: 69552-46-1
Purity:  ≥98.0%
Synonyms: Carbaprostacyclin; Carba-PGI2
Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation.
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1
1 Cited Publications
Cat. No.: HY-19354
CAS No.: 143901-35-3
Synonyms: Aglafolin; Rocaglamide U; (-)-Methyl rocaglate
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

Aglafoline inhibits PAF-induced platelet aggregation, with an IC50 value of 50 μM.
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1
1 Cited Publications
Cat. No.: HY-P1741A
Research Areas:  

Cardiovascular Disease

Fibrinogen-Binding Peptide TFA is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide TFA inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide TFA inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide TFA can be used for research on thrombosis .
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1
1 Cited Publications
Cat. No.: HY-108660
CAS No.: 1052087-90-7
Purity:  ≥98.0%
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

PSB-0739 is a high-affinity potent, competitive, nonselective platelet P2Y12 receptor antagonist with a Ki values of 24.9 nM. The P2Y12 receptor plays a crucial role in platelet aggregation. Antithrombotic effect .
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1
1 Cited Publications
Cat. No.: HY-N7614
CAS No.: 117210-12-5
Synonyms: Schidigerasaponin F2; Timosaponin AII
Anemarrhenasaponin A2 (Schidigerasaponin F2) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation .
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1
1 Cited Publications
Cat. No.: HY-10064S
CAS No.: 1265911-55-4
Ticagrelor-d7 is the deuterium labeled Ticagrelor. Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation .
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1
1 Cited Publications
Cat. No.: HY-14256
CAS No.: 166095-21-2
Purity:  98.01%
BMS-191095 is a selective activator of mitochondrial ATP-sensitive potassium (mitoKATP) channels. BMS-191095 inhibits human platelet aggregation by opening mitochondrial K(ATP) channels .
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1
1 Cited Publications
Cat. No.: HY-125989
CAS No.: 22140-20-1
Purity:  98.94%
Synonyms: 2-MeSAMP; 2-Methylthioadenosine 5′-monophosphate; 2-Methylthioadenosine 5′-phosphate
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation .
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1 Cited Publications
Cat. No.: HY-118752
CAS No.: 18046-21-4
Purity:  99.87%
Target:  

COX

Research Areas:  

Inflammation/Immunology

Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis .
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1
1 Cited Publications
Cat. No.: HY-B0683
CAS No.: 74397-12-9
Synonyms: 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206
Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research .
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1
1 Cited Publications
Cat. No.: HY-B1047
CAS No.: 2037-95-8
Synonyms: Carbonylsalicylamide
Target:  

Drug Intermediate

Research Areas:  

Neurological Disease

Carsalam (Carbonylsalicylamide; 2H-1,3-benzoxazine-2,4-dione) is a salicylamide derivative and precursor compound. Carsalam is a nonsteroidal anti-inflammatory agent and can inhibit platelet aggregation .
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1
1 Cited Publications
Cat. No.: HY-A0126A
CAS No.: 61849-14-7
Synonyms: Prostaglandin I2 sodium salt; Prostacyclin sodium salt; Flolan
Epoprostenol sodium (Prostaglandin I2) sodium salt, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation .
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