50 Results for "

GCGR

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "GCGR" in MCE Product Catalog:

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Cat. No.: HY-P704626
Pureté:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704627
Pureté:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705157
Pureté:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700411
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P810878
Synonyms: Glucagon receptor, GL-R, GCGR

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P11880
Target:  

GCGR

Domaines de recherche:  

Metabolic Disease

LY3324954 is a long-acting, highly selective glucagon receptor (GCGR) agonist. LY3324954 stimulates cAMP production via the hepatic GCGR signaling pathway and induces acute blood glucose elevation, while promoting FGF21 expression in the liver and plasma. LY3324954 reduces body weight and abdominal fat mass, increases energy expenditure, and effectively improves lipid homeostasis, insulin sensitivity, and glucose intolerance. LY3324954 can be used in obesity-related research .
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Cat. No.: HY-P3506S
Synonyms: LY3437943, Pro40(13C5,15N) TFA
Domaines de recherche:  

Metabolic Disease

Retatrutide, Pro40( 13C5, 15N) (LY3437943, Pro40( 13C5, 15N) TFA) is the 13C, 15N-labeled Retatrutide (HY-P3506). Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity .
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Cat. No.: HY-P3506S1
Synonyms: LY3437943, Phe22(13C9,15N) TFA
Domaines de recherche:  

Metabolic Disease

Retatrutide, Phe22( 13C9, 15N) (LY3437943, Phe22( 13C9, 15N) TFA is the 13C, 15N-labeled Retatrutide (HY-P3506). Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity .
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Cat. No.: HY-P11487
Target:  

GLP Receptor GCGR

Domaines de recherche:  

Cardiovascular Disease Metabolic Disease

UTG-4 is a GLP-1R, GIPR, and GCGR agonist with EC50 values of 126.3 pM, 29.2 pM, and 250.2 pM, respectively. UTG-4 binds to HSA (Kd = 14.6 μM). UTG-4 effectively alleviates endothelial-mesenchymal transition. UTG-4 promotes weight loss, inhibits food intake, improves glucose tolerance, and has a significant anti-atherosclerotic effect .
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Cat. No.: HY-181709
Synonyms: TG062
Target:  

GLP Receptor GCGR

Domaines de recherche:  

Metabolic Disease Inflammation/Immunology

TPM003 (TG062) is a triple agonist of GLP-1R, GIPR and GCGR, with EC50 values of 33.9, 12.5 and 92.9 pM, respectively. TPM003 suppresses appetite, regulates blood glucose, enhances insulin sensitivity, reduces gastrointestinal intolerance, promotes hepatic lipid mobilization and increases energy expenditure. TPM003 induces weight loss, improves metabolic parameters, reverses hepatic steatosis and optimizes liver function markers. TPM003 is applicable for research on obesity and non-alcoholic steatohepatitis .
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