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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
GCGR
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "GCGR" in MCE Product Catalog:
Cat. No.: HY-P10337
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OXM-7 is a dual agonist of GLP-1R (EC50=0.024 nM) and GCGR (EC50=0.082 nM). OXM-7 can enhance glucose-stimulated insulin secretion and hepatic glucose output. OXM-7 lowers blood glucose levels. OXM-7 improves lipid metabolism .
Cat. No.: HY-107129
CAS No.: 1019112-29-8
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MK-3577 is an orally effective glucagon receptor (GCGR) antagonist that reduces hepatic glucose production and lowers blood glucose levels by blocking glucagon receptors on target organs, primarily the liver. Pharmacokinetic analysis in domestic cats indicates that MK-3577 reaches peak levels 3 to 4 hours after oral administration, with a half-life of approximately 15 hours. MK-3577 can be used in diabetes research .
Cat. No.: HY-P4146B
Synonyms: BI 456906 sodium
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Cat. No.: HY-169707
CAS No.: 1421349-19-0
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GCGR antagonist 3 (example 1) is an antagonist of the glucagon receptor (GCGR) and can be used in diabetes research .
Cat. No.: HY-RS05324
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GCGR Human Pre-designed siRNA Set A contains three designed siRNAs for GCGR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05325
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Gcgr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gcgr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05326
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Gcgr Rat Pre-designed siRNA Set A contains three designed siRNAs for Gcgr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-118914
CAS No.: 362482-00-6
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Glucagon receptor antagonist inactive control (Compound 2) is a compound structurally similar to the glucagon receptor (GCGR) antagonist Glucagon receptor antagonist (Compound 1) but lacks antagonistic activity against glucagon receptor (GCGR). Glucagon receptor antagonist inactive control can be used as a negative control to study mechanisms related to glucagon receptor-mediated signaling pathways .
Cat. No.: HY-P5161
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Cat. No.: HY-P5161A
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Cat. No.: HY-159696
CAS No.: 1428588-67-3
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ISIS 449884 is a 2'-O-methoxyethyl antisense oligonucleotide that targets GCGR. ISIS 449884 has an ability to reduce hepatic glucose output and lower the blood glucose level. ISIS 449884 can be used for the study of type 2 diabetes mellitus (T2DM) .
Cat. No.: HY-159696A
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ISIS 449884 sodium is a 2'-O-methoxyethyl antisense oligonucleotide that targets GCGR. ISIS 449884 sodium has an ability to reduce hepatic glucose output and lower the blood glucose level. ISIS 449884 sodium can be used for the study of type 2 diabetes mellitus (T2DM) .
Cat. No.: HY-P11279
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TC2 is an efficient GIPR-preferring monomeric quadruple agonist that can respectively activate GIPR, GLP-1R, GcgR, and Y2R with IC50 values of 0.47, 2.1, 30, and 55 nM respectively. TC2 exhibits a significant GLP-1R preference, with a significant reduction in β-inhibitory protein 2 (βArr2) recruitment, while maintaining a strong cAMP signal. TC2 can be used for research on obesity and diabetes .
Cat. No.: HY-P11275
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Cat. No.: HY-P12143
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GCGR/GLP‐1 receptor agonist P1 is a dual GCGR/GLP-1R agonist. GCGR/GLP‐1 receptor agonist P1 activates human GCGR in vitro and induces the cyclic adenosine monophosphate (cAMP) signaling pathway. GCGR/GLP‐1 receptor agonist P1 is applicable to research related to type 2 diabetes and obesity .
Cat. No.: HY-P705976
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Rat
Source:
HEK293
Cat. No.: HY-P11818
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Cat. No.: HY-P703987
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
Cat. No.: HY-P703992
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GCGR; GL-R; Glucagon Receptor; MVAH; GGR
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
