430 Results for "

IP

" in MedChemExpress (MCE) Product Catalog:
Products (430)

430 Results for "IP" in MCE Product Catalog:

  • Isoforms Recommended:
1
1 Cited Publications
Cat. No.: HY-103642A
CAS No.: 141611-10-1
Purity:  99.8%
Synonyms: Inositol 1,4,5-trisphosphate trisodium; Ins(1,4,5)-P3 trisodium
Target:  

Calcium Channel

Research Areas:  

Metabolic Disease

D-myo-Inositol-1,4,5-triphosphate sodium salt is the trisodium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
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1
1 Cited Publications
Cat. No.: HY-79593
CAS No.: 475085-57-5
Synonyms: ACT-333679
MRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist.
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1 Cited Publications
Cat. No.: HY-K0233

MCE Anti-RFP Affinity Gel can be used for the detection and purification of native RFP, RFP mutants, and IP assays.

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1
1 Cited Publications
Cat. No.: HY-P87497

Host:  

Rat

Application:  

WB, IHC-P, mIHC, ELISA

Reactivity:  

Mouse

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1
1 Cited Publications
Cat. No.: HY-129139
CAS No.: 111613-04-8
Purity:  95.71%
Cyanidin-3-O-arabinoside is a p38 MAPK phosphorylation inhibitor. Cyanidin-3-O-arabinoside reduces the expression of VDAC1, inhibits mtROS accumulation, reverses cellular senescence, blocks excessive mitochondrial calcium influx, reduces the formation of mitochondria-associated endoplasmic reticulum membranes, and suppresses the VDAC1-IP3R1 interaction. Cyanidin-3-O-arabinoside activates hair follicle stem cell proliferation and improves the condition of slowed hair growth. Cyanidin-3-O-arabinoside is applicable to research related to colon cancer and androgenetic alopecia .
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1
1 Cited Publications
Cat. No.: HY-173425
CAS No.: 2912492-05-6
STING-IN-15 is an orally active STING inhibitor, with an IC50 of 116 nM against h-STING and an IC50 of 96.3 nM against m-STING. STING-IN-15 inhibits the STING signaling pathway in cells, reduces the secretion of IFN-β and IP-10, downregulates the expression of ISG15, ISG56 and TNF-α, and suppresses the phosphorylation of TBK1/IRF3. STING-IN-15 alleviates systemic and renal inflammation induced by STING agonists in mice, reduces tissue damage and the expression of interferon pathway genes, and inhibits spontaneous tissue inflammation in mice. STING-IN-15 can be used for the research of acute kidney injury and autoimmune/inflammatory diseases .
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1 Cited Publications
Cat. No.: HY-F0001R
CAS No.: 606-68-8
Synonyms: Disodium NADH (Standard)
NADH disodium salt (Disodium NADH) Standard is the analytical standard of NADH disodium salt (HY-F0001). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally effective reduced coenzyme. NADH disodium salt plays a role in regenerating electron donors during cellular energy metabolism, including glycolysis, β-oxidation, and the tricarboxylic acid (TCA) cycle. NADH disodium salt regulates calcium homeostasis by promoting the opening of IP3-gated Ca 2+ channels and inhibiting Ryanodine receptor, and affects mitochondrial function through direct interaction with VDAC. NADH disodium salt is used in cytoprotective studies related to cerebral ischemic injury, neurodegenerative diseases, aging, and signal transduction .
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1 Cited Publications
Cat. No.: HY-P700232AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL10; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 10; Prev. SCYB10; Small-Inducible Cytokine B10; Prev. INP10; C-X-C Motif Chemokine 10; IP-10; Protein 10 From Interferon (Gamma)-Induced Cell Line; GIP-10; Interferon-Inducible Cytokine IP-1
Species:  
Pig
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-128932
CAS No.: 75498-96-3
Purity:  99.83%
Synonyms: MT-141
Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits antibacterial activity. Cefminox sodium is a broad-spectrum, bactericidal cephalosporin antibiotic. Cefminox sodium also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ. Cefminox sodium upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium also prevents pulmonary arterial hypertension in rat model .
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1 Cited Publications
Cat. No.: HY-P7228
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL11; Interferon Gamma-Inducible Protein 9; Prev. SCYB11; C-X-C Motif Chemokine 11; Prev. SCYB9B; Beta-R1; I-TAC; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 9B; H174; Small Inducible Cytokine B11; IP-9; Small-Inducible Cytokine B11; B-R1; Alternative Protein CXCL11; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 11; ITAC; Interferon-Inducible T-Cell Alpha Chemoattractant; IP9; C-X-C Motif Chemokine Ligand 11; Chemokine (C-X-C Motif) Ligand 11
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-K0242

MCE Protein A Plus Magnetic Agarose Beads can be used for the detection and purification of IgG from serum, ascites fluid, cell culture supernatant and other antibody samples.

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1 Cited Publications
Cat. No.: HY-K0241

MCE Ni-NTA Magnetic Agarose Beads can be used for the detection and purification of His-tag proteins from various expression sources.

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1
1 Cited Publications
Cat. No.: HY-P71288
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SENP2; Sentrin (SUMO1) Specific Peptidase 2; SUMO Specific Peptidase 2; Sentrin/SUMO-Specific Protease SENP2; KIAA1331; SMT3-Specific Isopeptidase 2; SMT3IP2; Sentrin-Specific Protease 2; AXAM2; DKFZp762A2316; SUMO1/Sentrin/SMT3 Specific Peptidase 2; Smt3
Species:  
Human
Source:  
E. coli
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1 Cited Publications
Cat. No.: HY-N0620
CAS No.: 102841-43-0
Mulberroside C is one of the main bioactive components in white mulberry (Morus alba L.). Mulberroside C exhibits antiplatelet, antiviral and neutrophil-regulating activities, and binds to EV-A71 VP1 with a Kd value of 1.289 nM. Mulberroside C reduces the phosphorylation level of ERK, promotes the phosphorylation of IP3RI at the Ser 1756 site, and decreases calcium influx and calcium mobilization. Mulberroside C inhibits the expression of P-selectin (P-selectin). Mulberroside C upregulates the cyclic nucleotide signaling pathway in human platelets. Mulberroside C binds to IL-23R, upregulates the expression of G-CSF, GM-CSF and RASGRP1, and activates the RAS/ERK signaling pathway. Mulberroside C promotes neutrophil maturation, accelerates the recovery of leukopenia, and enhances the antibacterial activity of neutrophils. Mulberroside C inhibits the replication of hepatitis C virus in replicon cells. Mulberroside C prevents the uncoating and genome release of EV-A71, and inhibits the synthesis of viral proteins and RNA. Mulberroside C can be used in studies related to thrombosis-mediated cardiovascular diseases, chemotherapy- and radiotherapy-induced leukopenia, hepatitis C virus infection, and hand, foot and mouth disease .
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1 Cited Publications
Cat. No.: HY-P7229
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL11; Interferon Gamma-Inducible Protein 9; Prev. SCYB11; C-X-C Motif Chemokine 11; Prev. SCYB9B; Beta-R1; I-TAC; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 9B; H174; Small Inducible Cytokine B11; IP-9; Small-Inducible Cytokine B11; B-R1;
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P700169AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL11; Interferon Gamma-Inducible Protein 9; Prev. SCYB11; C-X-C Motif Chemokine 11; Prev. SCYB9B; Beta-R1; I-TAC; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 9B; H174; Small Inducible Cytokine B11; IP-9; Small-Inducible Cytokine B11; B-R1;
Species:  
Mouse
Source:  
E. coli
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1 Cited Publications
Cat. No.: HY-P702076
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RBCK1; Hepatitis B Virus X-Associated Protein 4; Prev. C20orf18; RING Finger Protein 54; UBCE7IP3; HOIL-1; RNF54; XAP3; XAP4; CDNA FLJ60704, Highly Similar To RanBP-Type And C3HC4-Type Zincfinger-Containing Protein 1; RanBP-Type And C3HC4-Type Zinc Finger
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P10849
CAS No.: 3061802-23-8
Target:  

Calcium Channel

Research Areas:  

Others

IP3RPEP6 is an IP3R competitive inhibitor. IP3RPEP6 has the IC50 values of 9.0 μM, 3.9 μM and 4.3 μM for IP3R1, IP3R2 and IP3R3, respectively. IP3RPEP6 does not affect the Ryanodine receptor and Cx43 hemichannels. IP3RPEP6 regulates calcium signaling within cells .
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Cat. No.: HY-110274
CAS No.: 500164-74-9
Purity:  99.65%
IP7e is a potent, brain-penetrant and orally active Nurr1 activator with an EC50 value of 3.9 nM .
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Cat. No.: HY-174868
CAS No.: 3055107-60-0
iP300w (Compound 9) is a Histone acetyltransferase p300 (KAT3B) inhibitor. iP300w can be used for synthesis of PROTAC BT-O2C (HY-174866) .
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