174 Results for "

beta-sheet backbone

" in MedChemExpress (MCE) Product Catalog:
Products (174)

174 Results for "beta-sheet backbone" in MCE Product Catalog:

Cat. No.: HY-P10699
CAS No.: 487036-63-5
Research Areas:  

Neurological Disease Cancer

MAX1 is a synthetic β-hairpin peptide that folds rapidly and self-assembles into a β-sheet-rich fibrous hydrogel network via non-covalent crosslinking. MAX1 hydrogel exhibits excellent shear-thinning and self-healing properties, enabling precise delivery via syringe and maintaining local retention after implantation. MAX1 hydrogel can uniformly encapsulate cells while preserving their viability and morphology, and protect growth factors (e.g., NGF) and chemotherapeutic drugs from degradation. MAX1 is applicable for spinal cord injury repair, medulloblastoma treatment, and three-dimensional high-throughput drug screening .
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Cat. No.: HY-140650
Research Areas:  

Cancer

Amine-PEG35000-amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. Amine-PEG35000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140655
Research Areas:  

Cancer

Biotin-PEG3400-amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. Biotin-PEG3400-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-P2554
CAS No.: 1373320-65-0
Target:  

Drug Intermediate

Research Areas:  

Others

Histone H3 (1-25), amide is a synthetic N-terminal tail peptide derived from histone H3, which can be used to identify substrates of histone methyltransferases (HMTs). Histone H3 (1-25), amide can serve as a parent backbone for the preparation of various modified peptides .
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Cat. No.: HY-140725
Research Areas:  

Cancer

Boc-NH-PEG2000-amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. Boc-NH-PEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-P4873
CAS No.: 118068-30-7
Target:  

Amylin Receptor

Research Areas:  

Neurological Disease

Amylin (20-29) (human) is the fragment of human islet amyloid polypeptide (hIAPP) or Amylin. Amylin is a 37-residue hormone. Amylin (20-29) (human) is responsible for the amyloidogenic propensities of the full length protein. Amylin (20-29) (human) can be transformed into its corresponding peptoid and retropeptoid sequences, to obtain beta-sheet breaker peptides as amyloid inhibitors .
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Cat. No.: HY-114884
CAS No.: 530112-00-6
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

RS-0406 is a beta-sheet breaker targeting Amyloid-β. RS-0406 can inhibits Aβ(1-42) fibrillogenesis and protect against Aβ(1-42)-induced cytotoxicity in primary hippocampal neurons. RS-0406 can be used for the research of neurological disease, such as Alzheimer's disease (AD) .
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Cat. No.: HY-P10155
CAS No.: 352653-12-4
Target:  

Inhibitory Antibodies

Research Areas:  

Others

VT5 is a β-sheet amphipathic peptide consisting of 26 amino acids. VT5 has the ability to form β-sheets for cellular internalization .
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Cat. No.: HY-P5340
CAS No.: 339091-39-3
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Amyloid-Forming peptide GNNQQNY is a biological active peptide. (This is a heptapeptide from the N-terminal prion-determining domain of the yeast protein Sup35 that forms amyloid fibrils. The availability of its detailed atomic oligomeric structure makes it a good model for studying the early stage of aggregation. The GNNQQNY dimer forms three stable sheet structures. in-register parallel, off-register parallel, and anti-parallel. The in-register parallel dimer, which is close to the amyloid beta-sheet structure, has few interpeptide hydrogen bonds, making hydrophobic interactions more important and increasing the conformational entropy compared to the anti-parallel sheet.)
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Cat. No.: HY-P11231
CAS No.: 2780353-11-7
Synonyms: FUS(364-369)-TAT
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

β4-TAT is a kind of β-sheet peptide foldamer. β4-TAT is composed of two parts: the β4 sequence (derived from the β-sheet fragment of the RRM domain of fused in sarcoma (FUS)) and the TAT sequence (a nuclear localization signal peptide that helps the entire peptide penetrate the nuclear membrane). β4-TAT influences FUS aggregation by targeting its RNA recognition motifs (RRM). β4-TAT effectively induces FUS aggregation within cells, leading to the death of cancer cells. β4-TAT can be used for the study of FUS .
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Cat. No.: HY-P5515
CAS No.: 409085-40-1
Target:  

Inhibitory Antibodies

Research Areas:  

Others

F(N-Me)GA(N-Me)IL is a biological active peptide. (Double N-methylated derivatives of amyloidogenic and cytotoxic partial IAPP sequence were found to be devoid of β-sheet structure, amyloidogenicity and cytotoxicity, The derivatives were able to interact with the native sequences and inhibit amyloid formation)
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Cat. No.: HY-P5967
CAS No.: 189064-06-0
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

Acetly-β Amyloid (15-20), Amide is a peptides fragment. Acetly-β Amyloid (15-20), Amide inhibits the β-sheet formation and stabilizes structure of Aβ (1–40) peptide. Acetly-β Amyloid (15-20), Amide can be used in study Alzheimer’s disease .
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Cat. No.: HY-P10534
CAS No.: 873582-78-6
ccβ is a 17-residue peptide that folds into a coiled-coil trimer at low temperatures and aggregates to form amyloid fibrils at high temperatures. ccβ serves as a simple model system for investigating α-helix to β-sheet conformational transitions and template-mediated aggregation processes associated with prion and amyloidogenic diseases. ccβ can be used in studies of prion diseases and Alzheimer's disease .
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Cat. No.: HY-170423
CAS No.: 322647-40-5
Research Areas:  

Others

18:1 (Δ9-Trans) PG is a phosphatidylglycerol with a phosphoglycerol backbone .
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Cat. No.: HY-W004283S1
CAS No.: 352431-40-4
Pentadecanoic acid-d3 is the deuterium labeled Pentadecanoic acid. Pentadecylic acid is a saturated fatty acid with a 15-carbon backbone.
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Cat. No.: HY-P5906
Synonyms: Citrullinated Aβ (1-40); Citrullinated Aβ40
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Citrullinated amyloid-β (1-40) peptide (human) (Citrullinated Aβ (1-40)) is a modified form of β-Amyloid (1-40) (HY-P0265) with a citrullination at the Arg5 site. Citrullinated amyloid-β (1-40) peptide (human) exhibits increased transient formation of soluble oligomers and insoluble aggregates composed of distorted parallel β-sheets compared with unmodified β-Amyloid (1-40) .
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Cat. No.: HY-W1008609
CAS No.: 182625-87-2
Research Areas:  

Others

(R)-GNA-A(Bz) phosphoramidite is a monophosphate nucleoside similar to DNA or RNA but differing in the composition of its sugar-phosphodiester backbone, using propylene glycol in place of ribose or deoxyribose.
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Cat. No.: HY-167993
CAS No.: 851050-23-2
Research Areas:  

Others

(R)-GNA-T phosphoramiditec (compound 7a) is a monophosphate nucleoside similar to DNA or RNA but differing in the composition of its sugar-phosphodiester backbone, using propylene glycol in place of ribose or deoxyribose .
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Cat. No.: HY-N12863
CAS No.: 145544-43-0
Myricetin-3-O-robinoside is a flavonoid isolated from cassava flowers by chromatographic techniques. Its structure consists of a myricetin backbone to which a robinose moiety is attached at the third position .
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Cat. No.: HY-P3159A
Research Areas:  

Others

VPM peptide TFA is a dithiol protease-cleavable peptide cross-linker. VPM peptide TFA can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .
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