RS-0406
RS-0406 is a beta-sheet breaker targeting Amyloid-β. RS-0406 can inhibits Aβ(1-42) fibrillogenesis and protect against Aβ(1-42)-induced cytotoxicity in primary hippocampal neurons. RS-0406 can be used for the research of neurological disease, such as Alzheimer's disease (AD).
For research use only. We do not sell to patients.
- CAS No.: 530112-00-6
- Formula: C16H14N4O2
- Molecular Weight:294.31
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
RS-0406 (10-100 μg/mL) inhibits 25 μM Aβ(1-42) fibrillogenesis and disassembles preformed Aβ(1-42) fibrils[1].
RS-0406 (10.3-3 μg/mL) ameliorates Aβ(1-42)-induced cytotoxicity in primary hippocampal neurons[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 530112-00-6
-
Molecular Weight 294.31
-
Formula C16H14N4O2
-
SMILES
OC1=CC=CC(NC2=NN=C(NC3=CC(O)=CC=C3)C=C2)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RS-0406 Related Classifications
HY-114884 Related Classifications
Powered by Bioz