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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
50 Results for "
fecal
" in MedChemExpress (MCE) Product Catalog:
Products (50)
50 Results for "fecal" in MCE Product Catalog:
Cat. No.: HY-W010516R
CAS No.: 97-61-0
Synonyms: 2-Methylpentanoic acid (Standard)
Cat. No.: HY-W012846R
CAS No.: 2418-52-2
Cat. No.: HY-182340
CAS No.: 143394-68-7
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KF20274 is an orally active adenosine A1 receptor antagonist. KF20274 increases the fecal pellet output in rats, and does not affect small intestinal propulsion or gastric emptying at defecation-increasing doses. KF20274 does not induce diarrhea at defecation-increasing doses. KF20274 can be used for the research of constipation .
Cat. No.: HY-182689
CAS No.: 2187395-66-8
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LY3358966 is an orally active sodium-dependent phosphate cotransporter 2b (NPT2b) inhibitor with a human IC50 of 32.4 nM, mouse IC50 of 43.9 nM, and rat of IC50 26.8 nM. LY3358966 inhibits NPT2b-mediated intestinal phosphate transport, decreases acute phosphate uptake into plasma, and increases fecal phosphate excretion. LY3358966 can be used for the research of renal disease .
Cat. No.: HY-19392
CAS No.: 263754-93-4
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LA-419 is an orally active nitric oxide (NO) donor. LA-419 can significantly reduce the amount of fecal worm eggs excreted, shorten the duration of egg excretion, and also decrease the number of larvae in the lungs and the number of parasitic females in the intestines in mice infected with S. venezuelensis. LA-419 can reduce the formation of atherosclerosis in apolipoprotein E-deficient mice. LA-419 can be used for the researches of infection and cardiovascular disease .
Cat. No.: HY-W750220
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4-Methylumbelliferyl β-D-glucuronide dihydrate is a fluorescent substrate and fluorescent probe used to detect the activity of β-D-glucuronidase. 4-Methylumbelliferyl β-D-glucuronide dihydrate also serves as a surrogate for assessing fecal coliform contamination in aquatic environments. 4-Methylumbelliferyl β-D-glucuronide dihydrate releases 4-methylumbelliferone via enzyme-mediated cleavage of the β-glycosidic bond; the latter emits fluorescence under alkaline conditions, with an excitation wavelength of 365-366 nm and an emission wavelength of 444 nm .
Cat. No.: HY-120274A
CAS No.: 1850385-65-7
Synonyms: (R)-AZD9977
Research Areas:
(R)-Balcinrenone ((R)-AZD9977) is an isomer of Balcinrenone (HY-120274). Balcinrenone is an orally active mineralocorticoid receptor modulator. Balcinrenone regulates mineralocorticoid receptor activity, inhibits aldosterone-induced target gene expression, and suppresses the activities of renal Toll-like receptor 4, MyD88 and NF-κB. Balcinrenone alleviates renal extracellular matrix remodeling, inflammatory cell infiltration, and the expression of renal injury markers. Balcinrenone restores myocardial perfusion reserve, regulates potassium homeostasis, and induces fecal potassium excretion. Balcinrenone is applicable to research on metabolism-related chronic kidney disease and heart failure .
Cat. No.: HY-159978
CAS No.: 1628848-73-6
Synonyms: EOS789
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Atidafonat is an orally active sodium-dependent phosphate transporter inhibitor, with IC50 values of 6.8, 1.5, and 1.7 μM against human NaPi-IIb, PiT-1, PiT-2, respectively; and IC50 values of 3.9, 1.9, and 1.7 μM against rat NaPi-IIb, PiT-1, PiT-2, respectively. Atidafonat inhibits intestinal phosphate absorption, increases fecal phosphate excretion, reduces urinary phosphate excretion, and decreases the levels of serum phosphate, FGF23, and adult parathyroid hormone. Atidafonat ameliorates ectopic thoracic aortic calcification, renal injury and hyperphosphatemia, and inhibits the expression of fibrosis markers. Atidafonat can be used for the research of hyperphosphatemia and chronic kidney disease-mineral and bone disorder (CKD-MBD) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
