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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
136 Results for "
non-nucleoside reverse-transcriptase
" in MedChemExpress (MCE) Product Catalog:
Products (136)
136 Results for "non-nucleoside reverse-transcriptase" in MCE Product Catalog:
Cat. No.: HY-105249
CAS No.: 878670-61-2
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RDEA 806 is an orally effective non-nucleoside reverse transcriptase (NNRT) inhibitor that exhibits potent in vitro inhibitory activity against wild-type HIV-1 (EC50 = 1.7 ng/mL) and NNRTI-resistant HIV-1. RDEA 806 rapidly reduces HIV-1 RNA viral load in vivo. RDEA 806 has a favorable biosafety profile. RDEA 806 can be used for research related to HIV-1 infection .
Cat. No.: HY-118711
CAS No.: 149486-68-0
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HI-346 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) for HIV-1 with an IC50 value against the HIV-1 virus strain (HTLV-IIIB) of 3 nM. HI-346 is a vaginal bactericidal contraceptive agent, with its sperm-killing activity having an EC50 value of 42 μM. HI-346 shows no cytotoxicity to normal cells at effective concentrations. HI-346 can be used in anti-HIV-1 and contraceptive research .
Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Atevirdine inhibits non-nucleoside reverse transcriptase that leads to viral multiplication .
Cat. No.: HY-169207
CAS No.: 3032803-00-9
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NNRT-IN-5 (compund 10d) is an orally available non-nucleoside reverse transcriptase inhibitor .
Cat. No.: HY-105491
CAS No.: 135812-34-9
Synonyms: NSC-629243
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UC-38 (NSC-629243) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) with anti-HIV activity .
Cat. No.: HY-131422
CAS No.: 205754-32-1
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(Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz (HY-10572), a non-nucleoside HIV-1 reverse transcriptase inhibitor .
Cat. No.: HY-149338
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NNRT-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor (EC50=0.01 μM) .
Cat. No.: HY-176169
CAS No.: 2892399-89-0
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DC20 is an orally active non-nucleoside reverse transcriptase inhibitor with an EC50 of 0.004 μM aganist HIV-1IIIB .
Cat. No.: HY-117477
CAS No.: 214287-90-8
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DPC-963 is an oral active non-nucleoside reverse transcriptase inhibitor with the IC50 of 18 nM. DPC-963 can be used for study of HIV .
Cat. No.: HY-132508S
CAS No.: 1142096-06-7
Cat. No.: HY-107001
CAS No.: 214287-88-4
Synonyms: (S)-DPC 961; DMP 961
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DPC 961 (DMP 961) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). DPC 961 is a potent and specific inhibitor of HIV-1 reverse transcriptase, which inhibits the activity of HIV-1 reverse transcriptase in a non-competitive manner, thereby preventing viral replication. DPC 961 can be used for research on AIDS .
Cat. No.: HY-10570S
CAS No.: 1051418-95-1
Cat. No.: HY-90005R
CAS No.: 269055-15-4
Synonyms: R165335 (Standard); TMC125 (Standard)
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Etravirine (Standard) is the analytical standard of Etravirine. This product is intended for research and analytical applications. Etravirine (R165335; TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
Cat. No.: HY-14294
CAS No.: 178979-85-6
Synonyms: S-1153
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Capravirine (S-1153) is an orally active non-nucleoside reverse transcriptase inhibitor (NNRTI) with potent antiviral activity. Capravirine inhibits replication of HIV-1 strains that are resistant to nucleoside/nucleotide reverse transcriptase inhibitors and other NNRTIs. Capravirine is metabolized by the cytochrome P450 enzyme CYP3A4 .
Cat. No.: HY-126900
CAS No.: 149486-73-7
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HI-253 is a non-nucleoside inhibitor of HIV-1 reverse transcriptase that has demonstrated greater activity than multiple anti-HIV compounds against both resistant and sensitive HIV-1 strains.
Cat. No.: HY-121611
CAS No.: 233271-65-3
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HI-236 is a potent non-nucleoside inhibitor of HIV-1 reverse transcriptase.?
HI-236 inhibits HIV activity (wild type HTLVIIB IC50p24 < 0.001 μM) .
Cat. No.: HY-150769
CAS No.: 3033486-43-7
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ZLM-66 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTIs) with an IC50 of 41 nM for wild-type (WT) HIV-1 reverse transcriptase and an EC50 value of 13 nM for wild-type HIV-1. ZLM-66 is a Doravirine (HY-16767) analogs. ZLM-66 can be used for the research of AIDS .
Cat. No.: HY-10570S1
CAS No.: 1051419-24-9
Cat. No.: HY-10570S2
CAS No.: 1051418-86-0
Synonyms: BI-RG 587-d8; NSC 641530-d8; NVP-d8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
