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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
117 Results for "
immunomodulator
" in MedChemExpress (MCE) Product Catalog:
Products (117)
117 Results for "immunomodulator" in MCE Product Catalog:
Cat. No.: HY-179009
Research Areas:
NOD2 agonist 4 (Compound 12b) is a potent NOD2 agonist with an EC50 of 44.1 nM. NOD2 agonist 4 induces cytokine production (MCP-1, IL-6 and IL-8) in peripheral blood mononuclear cells (PBMCs), both alone and in combination with Lipopolysaccharide (LPS) (HY-D1056). NOD2 agonist 4 can be used for the studies of NOD2-targeted immunomodulator or vaccine adjuvant .
Cat. No.: HY-106981
CAS No.: 137109-78-5
Synonyms: OR 1384
Research Areas:
Orazipone (OR 1384) is a small molecule immunomodulator with strong anti-inflammatory properties. Orazipone exerts its immunomodulatory effect by forming reversible thiol complexes, which bind to intracellular signaling proteins and the thiol groups of glutathione. Orazipone exhibits potent anti-eosinophilic activity by inducing apoptosis. Orazipone inhibits activation of inflammatory transcription factors NF-kB and STAT 1 and decreases inducible iNOS expression and NO production in response to inflammatory stimuli. Orazipone reduces NADPH oxidase activity and thereby decreases ROS production. Orazipone has a protective effect in intestinal radiation injury .
Cat. No.: HY-161131
CAS No.: 2399455-71-9
Research Areas:
Lenalidomide 4'-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide (HY-A0003) that can be used to synthesize PROTACs. Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4'-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups .
Cat. No.: HY-A0003BR
CAS No.: 847871-99-2
Synonyms: CC-5013 hemihydrate (Standard)
Research Areas:
Lenalidomide (hemihydrate) (Standard) is the analytical standard of Lenalidomide (hemihydrate). This product is intended for research and analytical applications. Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
Cat. No.: HY-139714
CAS No.: 2928463-38-9
IMD-vanillin is a novel imidazoquinolinone-NF-κB immunomodulator dimers.
Cat. No.: HY-100162
CAS No.: 105963-46-0
Target:
Research Areas:
TOK-8801 is a synthesized dihydroimidazothiazole carboxamide and is under development as an immunomodulator.
Cat. No.: HY-119527
CAS No.: 134381-30-9
Category:
Target:
Cat. No.: HY-139717
CAS No.: 2928463-40-3
IMD-biphenylA is a novel imidazoquinolinone-NF-κB immunomodulator dimer that improves the adjuvanticity of small molecule immune potentiators.
Cat. No.: HY-W747565
CAS No.: 89596-43-0
Synonyms: LTB4-APA
Target:
Research Areas:
Leukotriene B4-3-aminopropylamide (LTB4-APA) is a leukotriene immunomodulator .
Cat. No.: HY-N12988
CAS No.: 103680-87-1
Target:
Cat. No.: HY-139718
CAS No.: 2928463-41-4
Target:
Research Areas:
IMD-biphenylB is a potent imidazoquinolinone-NF-κB immunomodulator dimer that inhibits tumor proliferation while induces low systemic inflammation and reduces adjuvant toxicity.
Cat. No.: HY-139719
CAS No.: 2928463-42-5
Target:
Research Areas:
IMD-biphenylC is a novel imidazoquinolinone-NF-κB immunomodulator dimer that inhibits tumor proliferation while induces low systemic inflammation and reduces adjuvant toxicity.
Cat. No.: HY-139716
CAS No.: 2928463-39-0
Target:
Research Areas:
IMD-catechol is a novel imidazoquinolinone-NF-κB immunomodulator dimer that improves efficacy in a CT26 mouse colon carcinoma tumor model while eliciting minimal adjuvant toxicity.
Cat. No.: HY-W011890R
CAS No.: 38609-97-1
Research Areas:
Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer .
Cat. No.: HY-W748297
CAS No.: 3571-88-8
Target:
Research Areas:
NK 19 diiodide is a photosensitive cyanin dye. NK 19 diiodide is an immunomodulator capable of modifying immunological function of the impaired lymphocytes. NK 19 diiodide can be used for research of wounds and burns .
Synonyms: R850
Target:
Research Areas:
Sotirimod (R850) is a TLR7 agonist and immunomodulator. Sotirimod inhibits Apoptosis. Sotirimod is applicable to research related to actinic keratosis, early cervical HPV infection, and precancerous lesions of colorectal cancer .
Cat. No.: HY-100158
CAS No.: 83359-86-8
Research Areas:
FCE-20696 hydrochloride is an orally active immunomodulator. FCE-20696 hydrochloride also shows anti-inflammation and anti-infection effects. FCE-20696 hydrochloride can be used for the researches of infection, inflammation and immunology, such as adjuvant arthritis .
Cat. No.: HY-N2389R
CAS No.: 50773-42-7
Target:
Cat. No.: HY-117231
CAS No.: 126869-52-1
Target:
Research Areas:
RM 06 is an immunomodulator with a peptidyl hypoxanthine structure. RM 06 significantly reduces the number of lung metastases of melanoma cells in mice after lethal irradiation and bone marrow reconstitution by stimulating the activity of natural killer (NK) cells. RM 06 can be used for research related to melanoma .
Cat. No.: HY-139112
CAS No.: 83024-92-4
Target:
Research Areas:
Leukotriene B4 dimethyl amide, an immunomodulator, stimulates contraction of isolated guinea pig lung entities. Leukotriene B4 (LTB(4)) also stimulates human neutrophil migration, and LTB(4) antagonists may have anti-inflammatory activity in inflammatory pathophysiology .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
