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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
117 Results for "
immunomodulator
" in MedChemExpress (MCE) Product Catalog:
Products (117)
117 Results for "immunomodulator" in MCE Product Catalog:
Cat. No.: HY-131863
CAS No.: 2305936-70-1
Research Areas:
Pomalidomide 4'-alkylC8-acid is an E3 ubiquitin ligase ligand-Linker conjugate containing Pomalidomide (HY-10984). Pomalidomide is a third-generation immunomodulator that acts like a molecular glue. Pomalidomide interacts with the E3 ligase cereblon to induce degradation of the essential Ikaros transcription factor .
Cat. No.: HY-13718A
CAS No.: 237068-57-4
Synonyms: H-Glu-Trp-OH disodium; L-Glutamyl-L-tryptophan disodium
Target:
Research Areas:
Infection Cardiovascular Disease Inflammation/Immunology Cancer
Oglufanide (H-Glu-Trp-OH) disodium is a dipeptide immunomodulator isolated from calf thymus. Oglufanide disodium inhibits vascular endothelial growth factor (VEGF). Oglufanide disodium can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide disodium shows antitumor and anti-angiogenesis activities .
Cat. No.: HY-W062904
CAS No.: 248282-07-7
Synonyms: ABR-215062 sodium
Research Areas:
Laquinimod (ABR-215062) sodium, an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod sodium reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod sodium has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research .
Synonyms: ABR-215062-d5
Cat. No.: HY-13010R
CAS No.: 248281-84-7
Synonyms: ABR-215062 (Standard)
Target:
Research Areas:
Laquinimod (Standard) is the analytical standard of Laquinimod. This product is intended for research and analytical applications. Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research .
Cat. No.: HY-111203
CAS No.: 886208-76-0
Synonyms: MW189; MW01-6-189WH
Target:
TT-301 is a small-molecule immunomodulator capable of penetrating the blood-brain barrier. TT-301 exerts neuroprotective effects by binding to IL-1β, downregulating STAT3 expression, and modulating the JAK-STAT signaling pathway, thereby inhibiting microglial activation and the release of proinflammatory mediators, and alleviating neuroinflammation and brain edema. TT-301 is used in research on traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage, muscle wasting and atrophy, and periodontal disease .
Cat. No.: HY-168086
CAS No.: 2992690-04-5
Target:
Research Areas:
LSD1-IN-35 (Compound Z-1) is a selective LSD1 Inhibitor (IC50: 108 nM). LSD1-IN-35 inhibits the demethylation on H3K4me1/2. LSD1-IN-35 is an immunomodulator. LSD1-IN-35 promotes response of gastric cancer cells to T-cell killing effect by decreasing PD-L1 expression and further attenuates the PD-1/PD-L1 interaction .
Research Areas:
Dipropyl phthalate (Standard) is the analytical standard of Dipropyl phthalate (HY-B1944). This product is intended for research and analytical applications. Dipropyl phthalate is an immunomodulator. Dipropyl phthalate alters the activities of acid phosphatase, phenoloxidase and superoxide dismutase, increases the activity of β-glucuronidase in a dose-dependent manner, and elevates the mRNA level of hemocyanin in shrimp. Dipropyl phthalate activates the FoxO signaling pathway, interferes with cell proliferation and apoptosis, downregulates chondrocyte-related genes, and induces craniofacial cartilage developmental malformations in zebrafish embryos. Dipropyl phthalate can be used in studies related to Aeromonas veronii infection and micrognathia syndrome .
Synonyms: (-)-Eburnamonine (Standard); (-)-Vincamone (Standard)
Target:
Cat. No.: HY-P11663
CAS No.: 1683515-77-6
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Research Areas:
Cat. No.: HY-N10240
CAS No.: 1029520-85-1
Target:
Cat. No.: HY-124411R
CAS No.: 63329-53-3
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Research Areas:
Lobenzarit (Standard) is the analytical standard of Lobenzarit. This product is intended for research and analytical applications. Lobenzarit, an immunomodulator, possesses anti-oxidative .
Cat. No.: HY-P992105
CAS No.: 3062245-47-7
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Research Areas:
Cat. No.: HY-19031
CAS No.: 104317-64-8
Target:
Research Areas:
PCF-39 is a Hypoxanthine (HY-N0091) derivative and immunomodulator agent. PCF-39 induces an increased spleen cellularity .
Cat. No.: HY-180127
CAS No.: 2728747-80-4
Target:
Research Areas:
UR238 is a proteasome inhibitor. UR238 reduces levels of the immunomodulator HE4. UR238 decreases PDL1 expression on cells. UR238 exhibits anticancer activity against epithelial ovarian cancer .
Cat. No.: HY-184688
CAS No.: 1311612-43-7
ORS-22 is an immunomodulator with a Kd value of 9.2 nM for human LILRB4. ORS-22 binds directly to the extracellular domain of LILRB4, reverses immunosuppression, restores cytotoxic T cell function, recovers cytokine production, and reduces tumor cell viability. ORS-22 can be used in research related to colorectal cancer and acute myeloid leukemia .
Cat. No.: HY-114341
CAS No.: 34157-80-7
Synonyms: Kaempferol 5-O-β-D-glucopyranoside
Target:
Cat. No.: HY-182506
CAS No.: 64118-86-1
Synonyms: BM 12.531
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Research Areas:
Azimexon (BM 12.531) is an orally active immunomodulator with radioprotective and antitumor activities. Azimexon prolongs survival in multiple mouse models, enhances immunity and hematopoiesis, and alleviates radiation injury and tumor metastasis. Azimexon causes reversible hemolytic anemia in rats and dogs, and exerts therapeutic activity against adjuvant-induced arthritis in rats. Azimexon can be used for the research of lung carcinoma, leukemia, multiple myeloma, lung tumor, arthritis, breast cancer and AIDS‑related complex .
Cat. No.: HY-180559
Target:
Research Areas:
nAChR antagonist 2 is a selective nAChR antagonist. nAChR antagonist 2 inhibits nAChR subtype including hα9α10, hα9, and hα7 with IC50 values of 16.0 nM, 26.2 nM, and 336.3 nM, respectively, in Xenopus oocytes. nAChR antagonist 2 suppresses ATP-induced IL-1β release at nanomolar concentrations. nAChR antagonist 2 can be used for nonopioid analgesics and immunomodulators research .
Cat. No.: HY-184814
CAS No.: 1863978-69-1
Synonyms: C14-A-iE-LAN-G
Research Areas:
C14-Ala-D-Glu-(γ-meso)-LAN-Gly (OH) (C14-A-iE-LAN-G) is a NOD1 agonist and immunomodulator. C14-Ala-D-Glu-(γ-meso)-LAN-Gly (OH) promotes IL-10 production in cells. C14-Ala-D-Glu-(γ-meso)-LAN-Gly (OH) is applicable to research related to experimental autoimmune encephalomyelitis and colitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
