Kaempferol 5-glucoside
Kaempferol 5-glucoside (Kaempferol 5-O-β-D-glucopyranoside) is an orally active flavonol glycoside and immunomodulator. Kaempferol 5-glucoside is isolated from the aerial parts of Indigofera aspalathoides Vahl ex DC. Kaempferol 5-glucoside enhances delayed-type hypersensitivity in rats. Kaempferol 5-glucoside increases humoral antibody titers. Kaempferol 5-glucoside is used for the research of autoimmune diseases.
For research use only. We do not sell to patients.
- CAS No.: 34157-80-7
- Formula: C21H20O11
- Molecular Weight:448.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar albino (110-160 g, either sex)[1]
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Dosage:10 mg/kg; 20 mg/kg; 50 mg/kg; 100 mg/kg
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Administration:p.o.; daily
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Result:Increased neutrophil adhesion to 31.43% (10 mg/kg), 39.73% (20 mg/kg), 40.94% (50 mg/kg), and 41.07% (100 mg/kg), with all values significantly higher than control (p < 0.05).
Increased delayed-type hypersensitivity response footpad thickness by 17.5% (10 mg/kg, 0.68 mm), 24.6% (20 mg/kg, 0.72 mm), 49.42% (50 mg/kg, 0.84 mm), and 54.25% (100 mg/kg, 0.95 mm), with all values significantly higher than control (p < 0.05).
Increased primary humoral antibody titers to 18.92 (10 mg/kg), 26.91 (20 mg/kg), 35.68 (50 mg/kg), and 36.51 (100 mg/kg), with all values significantly higher than control (p < 0.001).
Increased secondary humoral antibody titers to 43.62 (10 mg/kg), 56.26 (20 mg/kg), 70.24 (50 mg/kg), and 72.92 (100 mg/kg), with all values significantly higher than control (p < 0.05).
Chemical Information
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CAS No. 34157-80-7
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Molecular Weight 448.38
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Formula C21H20O11
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SMILES
O(C1=C2C(OC(=C(O)C2=O)C3=CC=C(O)C=C3)=CC(O)=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
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Synonyms
Kaempferol 5-O-β-D-glucopyranoside
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Kaempferol 5-glucoside Related Classifications
HY-114341 Related Classifications
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- Kaempferol 5-glucoside
- 34157-80-7
- Kaempferol 5-O-β-D-glucopyranoside
- Others
- humoral antibody titers
- sheep red blood cells
- flavonol glycoside
- immunomodulatory activity
- autoimmune diseases
- neutrophil adhesion
- Wistar albino rats
- Indigofera aspalathoides
- delayed-type hypersensitivity reaction
- Inhibitor
- inhibitor
- inhibit