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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
560 Results for "
EC
" in MedChemExpress (MCE) Product Catalog:
Products (560)
560 Results for "EC" in MCE Product Catalog:
Art. -Nr.: HY-E70183
Synonyms: EC:3.2.1.20; GAA
Art. -Nr.: HY-E70185
Synonyms: EC:3.2.1.24; MAN2B1; LAMAN
Target:
Forschungsgebiete:
Lysosomal α-mannosidase (EC:3.2.1.24) is a low pH-activated exoglycosidase that hydrolyzes α-mannosidic linkages on mannan and N-linked oligosaccharides, and its activation requires Zn 2+. As the major exoglycosidase in the glycoprotein degradation pathway, lysosomal α-mannosidase cleaves α1,2-, α1,3- and α1,6-mannosidic linkages during a non-random, ordered degradation process to generate Man1GlcNAc1-2 for further lysosomal processing. Lysosomal α-mannosidase can be used in studies related to α-mannosidosis .
Art. -Nr.: HY-124067
CAS. Nr.: 1185908-92-2
EC-70124 is an orally active multikinase inhibitor targeting IKKβ and JAK2. EC-70124 blocks IkB phosphorylation and STAT3 (Tyr705) activation, suppressing NF-κB nuclear translocation and STAT3 transcriptional activity. EC-70124 reduces tumor growth and cancer stem cell (CSC) populations in prostate cancer cells and xenograft models. EC-70124 is promising for research of prostate cancer .
Synonyms: EC 2.6.1.1, Human liver; GOT, Human liver; AST, Human liver
Forschungsgebiete:
Aspartate aminotransferase (EC 2.6.1.1), Human liver is a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, Human liver comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, Human liver also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, Human liver is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers .
Art. -Nr.: HY-128940
CAS. Nr.: 625827-91-0
Target:
Forschungsgebiete:
EC089 is a cleavable linker used in conjugates of tubulysins and folates, and extracted from patent WO2011069116A1 .
Art. -Nr.: HY-109094
CAS. Nr.: 221139-79-3
Synonyms: EC-18
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Forschungsgebiete:
Mosedipimod is a monoacetyldiaglyceride that can be isolated from Cervus nippon Temminck. Mosedipimod is an orally active Toll-Like Receptor signaling inhibitor. Mosedipimod attenuates airway infammation by reducing myeloperoxidase expression in lung tissue. Mosedipimod is used in chronic obstructive pulmonary disease research .
Art. -Nr.: HY-E70186
CAS. Nr.: 55354-43-3
Synonyms: EC:3.1.6.12; ARSB
Art. -Nr.: HY-110296
CAS. Nr.: 1010694-08-2
Target:
Forschungsgebiete:
EC19 is an analogue of 13-cis retinoic acid (HY-15127). EC19 shows embryo toxicity. EC19 causes mild effects on upper beak outgrowth .
Art. -Nr.: HY-128938A
Reinheit: 98.04%
Target:
Forschungsgebiete:
EC1167 hydrochloride is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 hydrochloride has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC) .
Art. -Nr.: HY-128937
CAS. Nr.: 1602487-15-9
Target:
Forschungsgebiete:
EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy .
Art. -Nr.: HY-128938
CAS. Nr.: 1610414-00-0
Target:
Forschungsgebiete:
EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC) .
Art. -Nr.: HY-128939
CAS. Nr.: 1059477-92-7
Target:
Forschungsgebiete:
EC0488 is used to synthesize EC0531 with folate receptor (FR)-specific and anti-tumor activities .
Art. -Nr.: HY-P2631
CAS. Nr.: 742091-99-2
Target:
Forschungsgebiete:
Art. -Nr.: HY-E70188
Synonyms: EC:3.1.6.4; GALNS
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
