EC1167 hydrochloride
Based on 1 Customer Validation
EC1167 hydrochloride is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 hydrochloride has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC).
For research use only. We do not sell to patients.
- Purity: 98.04%
- Formula: C33H46ClN7O17S
- Molecular Weight:880.27
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 880.27
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Formula C33H46ClN7O17S
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Color White to off-white
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SMILES
SC[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(O)=O)NC(CC1=CC=C(CNC(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)C=C1)=O)=O)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 125 mg/mL (142.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1360 mL | 5.6801 mL | 11.3602 mL | 28.4004 mL |
| 5 mM | 0.2272 mL | 1.1360 mL | 2.2720 mL | 5.6801 mL | |
| 10 mM | 0.1136 mL | 0.5680 mL | 1.1360 mL | 2.8400 mL | |
| 15 mM | 0.0757 mL | 0.3787 mL | 0.7573 mL | 1.8934 mL | |
| 20 mM | 0.0568 mL | 0.2840 mL | 0.5680 mL | 1.4200 mL | |
| 25 mM | 0.0454 mL | 0.2272 mL | 0.4544 mL | 1.1360 mL | |
| 30 mM | 0.0379 mL | 0.1893 mL | 0.3787 mL | 0.9467 mL | |
| 40 mM | 0.0284 mL | 0.1420 mL | 0.2840 mL | 0.7100 mL | |
| 50 mM | 0.0227 mL | 0.1136 mL | 0.2272 mL | 0.5680 mL | |
| 60 mM | 0.0189 mL | 0.0947 mL | 0.1893 mL | 0.4733 mL | |
| 80 mM | 0.0142 mL | 0.0710 mL | 0.1420 mL | 0.3550 mL | |
| 100 mM | 0.0114 mL | 0.0568 mL | 0.1136 mL | 0.2840 mL |