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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
135 Results for "
PDMS interfaces
" in MedChemExpress (MCE) Product Catalog:
Products (135)
135 Results for "PDMS interfaces" in MCE Product Catalog:
Cat. No.: HY-W150930
CAS No.: 7597-22-0
Domaines de recherche:
mTOR ligand 1 (compound T2) is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). mTOR ligand 1 can serve as an active control for MHY1485 (HY-B0795, the target protein ligand of PD-M6 (HY-176166) .
Cat. No.: HY-176167
CAS No.: 3058330-88-1
Domaines de recherche:
mTOR ligand 1-C6-amino is a conjugate of a target protein ligand (HY-B0795) and a linker (HY-W008296). mTOR ligand 1-C6-amino can be used to synthesize PROTAC PD-M6 (HY-176166) .
Target:
Domaines de recherche:
SJM-3 is a positive allosteric modulator of different isoforms of the GABAA receptor. SJM-3 binds at the high-affinity benzodiazepine binding site at the α+/γ- subunit interface .
Cat. No.: HY-161798
Orpinolide is a withanolide analog that has anti-leukemia properties. It disrupts the internal balance of the Golgi apparatus, which is related to signaling through inositol 4-phosphate at the interface of the endoplasmic reticulum and Golgi membrane .
Cat. No.: HY-162119
CAS No.: 331431-75-5
Target:
Domaines de recherche:
PRL-IN-1 (compound 43) is a phosphatase of regenerating liver (PRL) inhibitor that directly binds the PRL1 trimer interface and obstructs PRL1 trimerization. PRL-IN-1 shows potent anticancer activities .
Cat. No.: HY-121068R
CAS No.: 17692-24-9
Domaines de recherche:
Bisoxatin (Standard) is the analytical standard of Bisoxatin. This product is intended for research and analytical applications. Bisoxatin is a laxative drug used for constipation. Bisoxatin binds substantially at the S-protein-ACE2 interface. Bisoxatin has the potential for inhibiting SARS-CoV-2 entry into the host research .
Domaines de recherche:
17α-Hydroxyprogesterone acetate (Standard) is the analytical standard of 17α-Hydroxyprogesterone acetate. This product is intended for research and analytical applications. 17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface .
Cat. No.: HY-164283
CAS No.: 1360461-57-9
Synonyms: 2-((2,3-Bis(oleoyloxy)propyl)dimethylammonio)ethyl hydrogen phosphate
Target:
Domaines de recherche:
DOCP (2-((2,3-Bis(oleoyloxy)propyl)dimethylammonio)ethyl hydrogen phosphate), characterized by their inverted charge orientation compared to traditional phosphocholine (PC) lipids, feature a quaternary amine positioned near the bilayer interface and a phosphate group that protrudes into the aqueous environment. This unique configuration of iPC lipids provides an exceptional opportunity to explore the biophysical properties and bioactivity implications resulting from the charge inversion at the bilayer surface.
Cat. No.: HY-W284558S
CAS No.: 2708287-31-2
Cat. No.: HY-136258
CAS No.: 2250025-94-4
Target:
Domaines de recherche:
nAChR agonist CMPI hydrochloride is a potent and selective positive allosteric modulator (PAM) of nAChR containing a α4:α4 subunit interface. nAChR agonist CMPI hydrochloride enhances the response of (α4)3(β2)2 nAChR to ACh (10 µM) with an EC50 of 0.26 µM. nAChR agonist CMPI hydrochloride has potential for the research of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity .
Cat. No.: HY-147255A
CAS No.: 2137847-77-7
Synonyms: (S)-ZM-H1505R
(S)-Canocapavir is the isomer of Canocapavir (HY-147255A). Canocapavir (ZM-H1505R) is an orally active HBV core protein-targeting antiviral agent. Canocapavir binds to the hydrophobic pocket at the dimer-dimer interface of HBV core protein (HBc), stimulating intracellular accumulation of nonfunctional HBV capsids, disrupting viral replication. Canocapavir interferes with the interaction between HBc and HBV large surface protein, resulting in diminished
production of empty virionsis. Canocapavir can be used for the research of hepatitis B virus (HBV) infection .
production of empty virionsis. Canocapavir can be used for the research of hepatitis B virus (HBV) infection .
Cat. No.: HY-175178
CAS No.: 1214645-87-0
Target:
Domaines de recherche:
Arrestin-3 modulator-1 (Compound LSH-3) is an arrestin-3 modulator. Arrestin-3 modulator-1 binds arrestin-3 at the interdomain interface. Arrestin-3 modulator-1 enhances recruitment of arrestin-3 to phosphorylation-deficient β2AR in cells with increase of FRET levels. Arrestin-3 modulator-1 can be used for congenital disorders like retinal degeneration, hyperthyroidism and obesity research .
Cat. No.: HY-161824
CAS No.: 2913194-20-2
Target:
Domaines de recherche:
Antiproliferative agent-52 is a tubulin inhibitor with a porcine tubulin KD of 29.65 μM. Antiproliferative agent-52 binds to the colchicine-binding site at the α-tubulin and β-tubulin interface and inhibits tubulin polymerization. Antiproliferative agent-52 exhibits antiproliferative activity against tumor cells. Antiproliferative agent-52 serves as a lead compound for development of thienopyrimidine and heterocyclic fused pyrimidines with antiproliferative activity. Antiproliferative agent-52 can be used for the research of ovarian cancer, non-small cell lung cancer .
Cat. No.: HY-131694
CAS No.: 69313-68-4
Target:
Domaines de recherche:
N-Dodecyllactobionamide is a sugar surfactant that can be used to the study of the effect of the structure of the sugar headgroup on the adsorption to liquid/vapor and solid/liquid interfaces .
Cat. No.: HY-179850
CAS No.: 1219008-49-7
Target:
Mal(11.1) is a new type of detergent that contains a short branched alkyl chain at the interface between the polar head and the non-polar tail.
Cat. No.: HY-179851
CAS No.: 1219008-64-6
Target:
Mal(11.2) is a new type of detergent that contains a short branched alkyl chain at the interface between the polar head and the non-polar tail.
Cat. No.: HY-179852
CAS No.: 1219008-68-0
Target:
Mal(12.1) is a new type of detergent that contains a short branched alkyl chain at the interface between the polar head and the non-polar tail.
Cat. No.: HY-107205
CAS No.: 13861-22-8
Target:
Domaines de recherche:
Propargyl methacrylate is an effective electrolyte additive used to stabilize the formation of the solid electrolyte interface (SEI) layer on meso-porous carbon microbeads (MCMB) in lithium-ion batteries .
Cat. No.: HY-117939
CAS No.: 171347-75-4
Target:
GM1489 is an MMP inhibitor that reduces degradation at the resin-dentin interface by inhibiting MMP activity, thereby enhancing bonding stability. GM1489 shows potential for researching strategies to improve bonding stability in both superficial and deep dentin .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
