149 Results for "

protease substrates

" in MedChemExpress (MCE) Product Catalog:
Products (149)

149 Results for "protease substrates" in MCE Product Catalog:

Cat. No.: HY-P5377
CAS No.: 221055-89-6
Synonyms: Cathepsin K substrate
Target:  

Ser/Thr Protease

Research Areas:  

Others

Abz-HPGGPQ-EDDnp (Cathepsin K substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption. It has potential as a drug target in autoimmune diseases and osteoporosis.This FRET peptide can be used to monitor selectively cathepsin K activity in physiological fluids and cell lysates. Abz-HPGGPQ-EDDnp [where Abz represents o-aminobenzoic acid and EDDnp represents N -(2, 4-dinitrophenyl)-ethylenediamine], a substrate initially developed for trypanosomal enzymes, is efficiently cleaved at the Gly-Gly bond by cathepsin K. This peptide is resistant to hydrolysis by cathepsins B, F, H, L, S and V, Ex/Em=340 nm/420 nm.)
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Cat. No.: HY-17367S2
CAS No.: 1092540-51-6
Synonyms: BMS-232632-d9
Atazanavir-d9 is the deuterium labeled Atazanavir. Atazanavir (BMS-232632), a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration . Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp) . Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM .
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Cat. No.: HY-E70354
CAS No.: 37259-58-8
Target:  

Endogenous Metabolite

Research Areas:  

Others

Protease for flavors is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
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Cat. No.: HY-E70331
Target:  

Endogenous Metabolite

Research Areas:  

Others

Acid Stable Protease is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
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Cat. No.: HY-P4018
CAS No.: 128340-47-6
Target:  

HIV Protease

Research Areas:  

Infection

HIV Protease Substrate IV is a substrate of HIV protease. HIV Protease Substrate IV can be used to measure the activity of HIV (human immunodeficiency virus) -1 protease .
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Cat. No.: HY-P2344
CAS No.: 223769-59-3
Target:  

HIV Protease

Research Areas:  

Infection

HIV Protease Substrate 1, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .
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Cat. No.: HY-P2344A
Target:  

HIV Protease

Research Areas:  

Infection

HIV Protease Substrate 1 TFA, a fiuorogenic HIV protease substrate, can be used to study enzymatic activity of HIV protease .
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Cat. No.: HY-P3950
CAS No.: 143147-74-4
Target:  

Fluorescent Dye

Research Areas:  

Others

Fluorescent Substrate for Asp-Specific Proteases is a substrate to cleave specifically the Asp-Val bond .
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Cat. No.: HY-153921
CAS No.: 135822-00-3
Target:  

Dengue Virus

Research Areas:  

Infection

DEPN-8 is a WNV protease substrate. DEPN-8 is used for dengue virus protease inhibitor development .
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Cat. No.: HY-P4773
CAS No.: 396716-24-8
Target:  

HSV

Research Areas:  

Infection

HSV-1 Protease substrate is a peptide substrate for HSV-1 (Herpes Simplex Virus Type 1) protease, and the specificity constant (kcat/Km) at pH 7.5 for cleavage is 5.2 M -1 s -1 .
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Cat. No.: HY-P5510
CAS No.: 188530-20-3
Synonyms: HCV NS3 protease substrate
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM.
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Cat. No.: HY-P4492
CAS No.: 80651-94-1
Target:  

Inhibitory Antibodies

Research Areas:  

Metabolic Disease

Suc-Phe-Leu-Phe-SBzl is a substrate of ATP-dependent protease .
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Cat. No.: HY-P2715
CAS No.: 73554-93-5
Target:  

Fluorescent Dye

Research Areas:  

Others

Boc-Leu-Ser-Thr-Arg-AMC is a fluorogenic AMC-linked protease substrate .
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Cat. No.: HY-P4777
CAS No.: 163265-38-1
Synonyms: Dabcyl-CMV-Edans
Target:  

Fluorescent Dye

Research Areas:  

Infection

Dabcyl-RGVVNASSRLA-Edans (Dabcyl-CMV-Edans) is a fluorogenic substrate for human cytomegalovirus (HCMV) protease .
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Cat. No.: HY-P4777A
Synonyms: Dabcyl-CMV-Edans TFA
Target:  

Fluorescent Dye

Research Areas:  

Infection

Dabcyl-RGVVNASSRLA-Edans (Dabcyl-CMV-Edans) is a fluorogenic substrate for human cytomegalovirus (HCMV) protease .
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Cat. No.: HY-P11081
Target:  

Enterovirus

Research Areas:  

Infection

P08 is a substrate for EV71 3C protease cleavage with a Kcat/Km of 11.8 mM −1 min −1 .
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Cat. No.: HY-P4209A
Target:  

Virus Protease

Research Areas:  

Others

Boc-GRR-AMC (TFA) is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity .
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Cat. No.: HY-137495
CAS No.: 65113-67-9
Purity:  97.36%
Target:  

PAI-1 Ser/Thr Protease

Research Areas:  

Cancer

GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like serine protease urokinase-type plasminogen activator (uPA) inhibitor .
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Cat. No.: HY-137495A
Target:  

PAI-1 Ser/Thr Protease

Research Areas:  

Cancer

GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like serine protease urokinase-type plasminogen activator (uPA) inhibitor .
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Cat. No.: HY-P5312
Target:  

Virus Protease

Research Areas:  

Infection

Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr is a WNV NS2B-NS3 protease substrate. Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr is used for WNV NS2B-NS3 protease substrate peptide selective inhibitor development .
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