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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
992 Results for "
NSC
" in MedChemExpress (MCE) Product Catalog:
Products (992)
992 Results for "NSC" in MCE Product Catalog:
Cat. No.: HY-Y0453S
CAS No.: 1219803-75-4
Synonyms: Ethyl isonipecotate-d9; NSC 93792-d9; Piperidin-4-carboxylic acid ethyl ester-d9
Synonyms: Dihydrocholesterol-d5; 5α-Cholestanol-d5; NSC 18188-d5
Cat. No.: HY-W700927
CAS No.: 1356930-28-3
Synonyms: N-Formyl-S-leucine-d3; N-Formylleucine-d3; NSC 334321-d3
Cat. No.: HY-Y0860S
CAS No.: 169397-96-0
Synonyms: 1,6-Dibromohexane-d12; Hexamethylene dibromide-d12; NSC 7306-d12
Cat. No.: HY-Y0999S
CAS No.: 1398065-76-3
Synonyms: Methyl heptyl ketone-d5; Methyl n-heptyl ketone-d5; NSC 14760-d5
Cat. No.: HY-41463S
CAS No.: 1219803-44-7
Synonyms: 4-(Butylamino)benzoic acid-d7; NSC 44300-d7; p-Butylaminobenzoic acid-d7
Cat. No.: HY-A0161S
Synonyms: Clofedanol-13C6; Calmotusin-13C6; NSC 113595-13C6
Cat. No.: HY-B0213S1
Synonyms: Sulfametoxydiazine-13C6; 5-Methoxysulfadiazine-13C6; NSC 683528-13C6
Cat. No.: HY-W777393
CAS No.: 1189992-05-9
Synonyms: 7-Hydroxycoumarin-13C6; Hydrangin-13C6; NSC 19790-13C6
Cat. No.: HY-Y0978S4
CAS No.: 145143-01-7
Synonyms: N-tert-Butoxycarbonyl-2-aminoacetic acid-13C,15N; NSC 127669-13C,15N
Cat. No.: HY-12008S1
CAS No.: 1210610-07-3
Synonyms: CP-358774-13C6 hydrochloride; NSC 718781-13C6 hydrochloride; OSI-774-13C6 hydrochloride
Research Areas:
Erlotinib- 13C6 hydrochloride (CP-358774- 13C6 hydrochloride) is the 13C-labeled Erlotinib Hydrochloride (HY-12008). Erlotinib (CP-358774) Hydrochloride is a selective, orally active EGFR tyrosine kinase inhibitor. Erlotinib Hydrochloride also acts as a substrate and inhibitor of OATP2B1, with an IC50 of approximately 0.079 μM for inhibiting OATP2B1-mediated uptake of estrone 3-sulfate. Erlotinib Hydrochloride blocks EGFR phosphorylation, downstream signal transduction, as well as the growth and proliferation of cancer cells. Erlotinib Hydrochloride inhibits MMP-10-mediated renal injury, fibrotic lesions, the ERK1/2, GSK-3β and β-catenin signaling pathways, as well as the deposition of fibronectin, α-SMA, collagen and renal injury markers. Erlotinib Hydrochloride is metabolized via CYP3A to produce the active metabolite OSI-420. Erlotinib Hydrochloride can be used in research related to non-small cell lung cancer, gastric cancer, papillary renal cell carcinoma, EGFR inhibitor resistance and renal fibrosis .
Cat. No.: HY-50896S1
CAS No.: 1211107-68-4
Synonyms: CP-358774-13C6; NSC 718781-13C6; OSI-774-13C6
Cat. No.: HY-W771024
CAS No.: 2997580-43-3
Synonyms: 4-(4-Methylphenyl)sulfonyloxybutyl 4-methylbenzenesulfonate-13C4; NSC 521542-13C4
Cat. No.: HY-141919S
CAS No.: 1261170-84-6
Synonyms: 4-Iodobromobenzene-13C6; 4-Iodophenyl bromide-13C6; NSC 8033-13C6
Cat. No.: HY-N1150S8
CAS No.: 1821188-00-4
Synonyms: DThyd-13C10,15N2; NSC-13C10,15N2
Cat. No.: HY-Y1051S
CAS No.: 2708286-89-7
Synonyms: Cyclohexanecarboxylic acid chloride-d11; Cyclohexanoic acid chlorid-d11e; Cyclohexanoyl chloride-d11; Cyclohexylcarbonyl chloride-d11; Hexahydrobenzoyl chloride-d11; NSC 85181-d11
Cat. No.: HY-118560S
Synonyms: NSC 6598-13C2; Herbaflorat-13C2; Greenyl acetate-13C2; Verdyl acetate-13C2
Cat. No.: HY-Y1322S
CAS No.: 1173020-30-8
Synonyms: Celluflex TPP-d15; DHPF 005-d15; Disflamol TP-d15; Disflamoll TP-d15; NSC 57868-d15; Phenyl phosphate ((PhO)3PO)-d15; Phoscon FR 903N-d15
Cat. No.: HY-Y0659S1
Synonyms: 1,2,3,4-Tetrahydroquinoline-13C3,15N; 3,4-Dihydro-2H-quinoline-13C3,15N; Kusol-13C3,15N; NSC 15311-13C3,15N; THQ-13C3,15N; Quinoline, 1,2,3,4-tetrahydro-13C3,15N
Cat. No.: HY-180496
CAS No.: 2197964-95-5
Target:
Research Areas:
(S)-NSC 121182 is an isomer of NSC 121182 (HY-180492). (S)-NSC 121182 does not cause statistically significant changes in CIRBP levels. (S)-NSC 121182 can be used in research on hypothermia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
