594 Results for "

Integrin

" in MedChemExpress (MCE) Product Catalog:
Products (594)

594 Results for "Integrin" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P0204
CAS No.: 117399-93-6
Synonyms: Endothelin 3 (Rat,Human)
Research Areas:  

Neurological Disease

Endothelin-3, human, mouse, rabbit, rat (Endothelin 3 (Rat,Human)) is an adhesion stimulant. Endothelin-3, human, mouse, rabbit, rat stimulates the adhesion of enteric neural crest cells to various ECM components. Endothelin-3, human, mouse, rabbit, rat plays an important role in the maintenance and self-renewal of intestinal progenitor cells, participates in the migration of enteric neural crest cells, and helps maintain a suitable environment for the colonization of enteric neural crest cells. Endothelin-3, human, mouse, rabbit, rat acts synergistically with the β1-integrin signaling pathway during enteric nervous system development. Endothelin-3, human, mouse, rabbit, rat can be used in studies related to distal aganglionosis .
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1
1 Cited Publications
Cat. No.: HY-P0204A
Synonyms: Endothelin 3 (Rat,Human) TFA
Research Areas:  

Neurological Disease

Endothelin-3, human, mouse, rabbit, rat TFA (Endothelin 3 (Rat,Human) TFA) is an adhesion stimulant. Endothelin-3, human, mouse, rabbit, rat TFA stimulates the adhesion of enteric neural crest cells to various ECM components. Endothelin-3, human, mouse, rabbit, rat TFA plays an important role in the maintenance and self-renewal of intestinal progenitor cells, participates in the migration of enteric neural crest cells, and helps maintain a suitable environment for the colonization of enteric neural crest cells. Endothelin-3, human, mouse, rabbit, rat TFA acts synergistically with the β1-integrin signaling pathway during enteric nervous system development. Endothelin-3, human, mouse, rabbit, rat TFA can be used in studies related to distal aganglionosis .
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1
1 Cited Publications
Cat. No.: HY-P7831
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3
Species:  
Rhesus Macaque Cynomolgus
Source:  
HEK293
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1 Cited Publications
Cat. No.: HY-125792
CAS No.: 331949-35-0
Purity:  99.69%
Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 μM) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and β2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury .
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1 Cited Publications
Cat. No.: HY-NP132A
Recombinant humanized type III collagen (MW 55900) is a type III collagen with a molecular weight of 55900 Da. Recombinant humanized type III collagen has various biological functions, such as promoting skin extracellular matrix regeneration and improving the cell microenvironment. Recombinant humanized type III collagen inhibits the proliferation, migration, and invasion of breast cancer cells. Type III collagen functions in cell adhesion, migration, proliferation and differentiation through its interaction with integrins .
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1 Cited Publications
Cat. No.: HY-101473
CAS No.: 851333-14-7
Purity:  99.94%
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

EMD527040 is a potent and highly selective αvβ6 antagonist with antifibrotic activities. EMD527040 can be used for carcinoma and liver fibrosis research .
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1 Cited Publications
Cat. No.: HY-P99291
CAS No.: 892553-42-3
Synonyms: LM609; MEDI-522

Target:  

Integrin Apoptosis Akt

Research Areas:  

Cancer

Etaracizumab (LM 609) is an αvβ3 integrin IgG mAb. Etaracizumab is developed to target αvβ3+ cancer cells via NK cell-mediated cytotoxicity. Etaracizumab sterically hinders access of large ligands to the RGD-binding pocket, without obstructing it. Etaracizumab decreases p-Akt in vitro. Etaracizumab can decrease cancer proliferation and invasion. Etaracizumab induces tumor cell apoptosis, and inhibition ofαvβ3-mediated cell adhesion, endothelial cell migration and osteoclast-mediated bone resorption. Etaracizumab can be studied in anti-tumor research against cancers such as ovarian cancer, metastatic melanoma as well as advanced solid tumors. Recommend Isotype Control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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1 Cited Publications
Cat. No.: HY-P0132
CAS No.: 110590-64-2
Synonyms: Laminin Fragment 929-933
Target:  

NO Synthase

Research Areas:  

Cancer

YIGSR (Laminin Fragment 929-933) is a polypeptide that inhibits tumor growth and metastasis of leukemia cells. YIGSR specifically binds to the 67kDa laminin receptor and regulates the expression of eNOS in endothelial cells. YIGSR can be used in leukemia-related research .
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1 Cited Publications
Cat. No.: HY-P99524
CAS No.: 1238217-55-4
Synonyms: GBR500

Target:  

Integrin

Vatelizumab (GBR500) is a monoclonal antibody that targets the α2 subunit (CD49b) of very late antigen 2 (VLA-2). Vatelizumab can be used for research on multiple sclerosis .
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Cat. No.: HY-130119
CAS No.: 2378617-67-3
Target:  

Integrin

Research Areas:  

Cancer

Integrin-IN-2 (compound 39) is an orally bioavailable pan αv integrin inhibitor. Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively .
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Cat. No.: HY-P2532
CAS No.: 278792-07-7
Target:  

Integrin

Research Areas:  

Others

Integrin Binding Peptide is derived by fibronectin. Integrin Binding Peptide can be used for PEG hydrogel preparation .
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Cat. No.: HY-18668
CAS No.: 593274-97-6
Target:  

Integrin

Research Areas:  

Cancer

Integrin antagonist 27 (Compound 27) is a small molecule integrin αvβ3 antagonist with an affinity of 18 nM. Integrin antagonist 27 can be combined with Paclitaxel (HY-B0015) to selectively target αvβ3-positive metastatic cancer cells. Integrin antagonist 27 is used as an anticancer agent .
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Cat. No.: HY-P10045
CAS No.: 1335046-19-9
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Integrin signaling inhibitor, mP13 is an inhibitor of integrin signaling. Integrin signaling inhibitor, mP13 inhibits inside-out and outside-in signaling, including fibrinogen binding, platelet adhesion, and clot retraction .
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Cat. No.: HY-P73865
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC; CD51; Integrin Subunit Alpha V; Antigen Identified By Monoclonal Antibody L230; ITGB8; Integrin, Beta 8; Integrin Subunit Beta 8; Integrin Beta; Integrin Beta-8
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P83363
Synonyms: Integrin beta-5

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Hamster, Rat

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Cat. No.: HY-P704069
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-P73869
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ITGA8; Integrin, Alpha 8; Integrin Subunit Alpha 8; Integrin Alpha-8; ITGB1; Very Late Activation Protein, Beta Polypeptide; Prev. MSK12; Integrin VLA-4 Beta Subunit; Prev. FNRB; VLA-4 Subunit Beta; Prev. MDF2; Integrin Beta 1; GPIIA; Integrin Beta; Integ
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P73869A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA8; Integrin, Alpha 8; Integrin Subunit Alpha 8; Integrin Alpha-8; ITGB1; Very Late Activation Protein, Beta Polypeptide; Prev. MSK12; Integrin VLA-4 Beta Subunit; Prev. FNRB; VLA-4 Subunit Beta; Prev. MDF2; Integrin Beta 1; GPIIA; Integrin Beta; Integ
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700750
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA10; Integrin, Alpha 10; Integrin Subunit Alpha 10; PRO827; Integrin Alpha-10; ITGB1; Very Late Activation Protein, Beta Polypeptide; Prev. MSK12; Integrin VLA-4 Beta Subunit; Prev. FNRB; VLA-4 Subunit Beta; Prev. MDF2; Integrin Beta 1; GPIIA; Integrin
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700751
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGA10; Integrin, Alpha 10; Integrin Subunit Alpha 10; PRO827; Integrin Alpha-10; ITGB1; Very Late Activation Protein, Beta Polypeptide; Prev. MSK12; Integrin VLA-4 Beta Subunit; Prev. FNRB; VLA-4 Subunit Beta; Prev. MDF2; Integrin Beta 1; GPIIA; Integrin
Species:  
Mouse
Source:  
HEK293
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