2378617-67-3
2378617-67-3
Chemical Structure
Integrin-IN-2
- CAS 番号: 2378617-67-3
- Formula:C27H30N4O3
- Molecular Weight:458.55
IUPAC Name: 3-(3-cyclopropylphenyl)-3-((5-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy)pyridin-2-yl)amino)propanoic acid
InChIKey: APVMUACUMAKXLA-UHFFFAOYSA-N
SMILES: O=C(O)CC(C1=CC=CC(C2CC2)=C1)NC3=NC=C(OCCC4=NC5=C(CCCN5)C=C4)C=C3
Biological Activity: Integrin-IN-2 (compound 39) is an orally bioavailable pan αv integrin inhibitor. Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively[1].
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Integrin-IN-2 | 98.23% | Integrin-IN-2 (compound 39) is an orally bioavailable pan αv integrin inhibitor. Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively. | ||||||||||||||||||||
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