1299 Results for "

SARS-CoV 3CLPpro

" in MedChemExpress (MCE) Product Catalog:
Products (1299)

1299 Results for "SARS-CoV 3CLPpro" in MCE Product Catalog:

Cat. No.: HY-P703544
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Spike glycoprotein; S glycoprotein; E2; Peplomer protein; Spike protein S1; Spike protein S2; Spike protein S2'; S; 2
Species:  
Virus
Source:  
Sf9 insect cells
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Cat. No.: HY-P705083
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Spike; S protein; Spike glycoprotein; S glycoprotein; B.1.351; 20H/501Y.V2
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-B1028R
CAS No.: 16816-67-4
Synonyms: D-Pantethine (Standard); LBF disulfide (Standard)
Pantethine (Standard) is the analytical standard of Pantethine. This product is intended for research and analytical applications. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration [3] .
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Cat. No.: HY-B1028S
Synonyms: D-Pantethine-15N2; LBF disulfide-15N2
Pantethine- 15N2 is the 15N2 labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration [3] .
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Cat. No.: HY-138794A
CAS No.: 2417089-73-5
Target:  

Deubiquitinase

Research Areas:  

Cancer

(Rac)-XL177A is the racemic isomer of XL177A (HY-138794). XL177A is a covalent USP7 inhibitor that blocks the deubiquitinase activity of USP7. XL177A destabilizes non-canonical PRC1 complexes or KDM6A and reduces chromatin deposition of H2AK119Ub, thereby relieving the repression of neuronal differentiation programs. Meanwhile, XL177A also regulates the ELOF1-UVSSA-USP7-nuclear β-catenin axis, decreasing the transcription levels of related proteins and the accumulation of nuclear β-catenin. XL177A exerts antiviral effects by reducing the expression levels of coronavirus receptors, and exhibits inhibitory activity against APC-mutated colorectal cancer cells, neuroblastoma, and coronaviruses including SARS-CoV-2 variants. XL177A is mainly used in studies related to colorectal cancer, neuroblastoma, and coronavirus infections [3] .
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Cat. No.: HY-145973A
Purity:  ≥99.0%
Synonyms: m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium solution (100 mM)
3’OMe-m7GpppAmpG (m7(3'OMeG)(5')ppp(5')(2'OMeA)pG) ammonium solution (100 mM) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3’OMe-m7GpppAmpG ammonium solution (100 mM) effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3’OMe-m7GpppAmpG ammonium solution (100 mM) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research [3] .
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Cat. No.: HY-N0181A
CAS No.: 474-69-1
Synonyms: 9β,10α-Ergosterol
Lumisterol (9β,10α-Ergosterol) is a photoproduct of 7-dehydrocholesterol, present in the skin, and acts as an orally active VDR non-genomic modulator and ROR inverse agonist. Lumisterol binds to the SARS-CoV-2 Mpro substrate-binding pocket and the RdRP active site, inhibiting enzyme activity. Lumisterol induces NRF2-regulated antioxidant responses, p53 phosphorylation and nuclear translocation, and intracellular free radical scavenging. Lumisterol inhibits the proliferation of epidermal keratinocytes and melanoma cells, modulates cell cycle progression, and suppresses basal and TNFα-induced NFκB transcriptional activity. Lumisterol inhibits RORγ transcriptional activity and IL-17 production. Lumisterol is used in research on UVB-induced skin damage, melanoma, psoriasis, vitamin D deficiency, and COVID-19 [3] .
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Cat. No.: HY-P705088
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Spike; S protein; Spike glycoprotein; S glycoprotein; B.1.617.2; 21A/S:478K
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P76600
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: 2019-nCoV RBD Protein; 2019-nCoV Spike RBD Protein; S protein RBD; 2019-nCoV S protein RBD
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P77635
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.;≥ 95%, as determined by HPLC.
Synonyms: S1 protein; Spike protein S1; Spike,S1 protein; S glycoprotein Subunit1
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P703529
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Nucleoprotein; Nucleocapsid protein; NC; Protein N; N; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; N; Ribonucleoprotein; RNA-binding; Viral nucleoprotein
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P703530
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Nucleoprotein; Nucleocapsid protein; NC; Protein N; N; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; N; Ribonucleoprotein; RNA-binding; Viral nucleoprotein
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P705090
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Spike; S protein; Spike glycoprotein; S glycoprotein; AY.1/AY.2/AY.3; Delta Plus
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-132280
CAS No.: 110101-66-1
Purity:  98.11%
Synonyms: U 74006F free base
Tirilazad (U 74006F free base) is a neuroprotective agent. Tirilazad can also bind tightly to the main protease of the COVID-19 virus and exert anti-SARS-CoV-2 activity. Tirilazad scavenges hydroxyl and lipid peroxyl free radicals and maintains the levels of endogenous antioxidants. Tirilazad reduces cerebral infarct volume and improves neurobehavioral scores in animal models of focal ischemia. Tirilazad can be used in research related to ischemic stroke and subarachnoid hemorrhage .
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Cat. No.: HY-162507
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

2'-RIBOTAC-U recruiter-linker (Compound 9) consists of RNase L recruiter and linker. 2'-RIBOTAC-U recruiter-linker is reacted separately with 2’-azido-uridine or 5’-azidomethyl-uridine via copper-catalyzed click chemistry, resulting in the formation of 2’-RIBOTAC-U and 5’-RIBOTAC-U, respectively. 2’-RIBOTAC-U has anti-SARS-CoV-2 activity .
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Cat. No.: HY-W012531R
CAS No.: 614-60-8
2-Hydroxycinnamic acid (Standard) is the analytical standard of 2-Hydroxycinnamic acid. This product is intended for research and analytical applications. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .
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Cat. No.: HY-W012531S2
2-Hydroxycinnamic acid-d4 is deuterium labeled 2-Hydroxycinnamic acid. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity [3] .
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Cat. No.: HY-P76590
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 3CL Protease; 3CL Proteinase; 3C-like main protease; 3CL-Mpro; CoVID-19; M Proteinase; Main Protease; Mpro
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P78279
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: S1 protein; Spike protein S1; Spike,S1 protein; S glycoprotein Subunit1
Species:  
Virus
Source:  
HEK293
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Cat. No.: HY-P703531
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Nucleoprotein; Nucleocapsid protein; NC; Protein N; N; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; N; Ribonucleoprotein; RNA-binding; Viral nucleoprotein
Species:  
Virus
Source:  
Sf9 insect cells
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