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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1514 Results for "
polymerization
" in MedChemExpress (MCE) Product Catalog:
Products (1514)
1514 Results for "polymerization" in MCE Product Catalog:
Cat. No.: HY-N0488AR
CAS No.: 57-22-7
Synonyms: Leurocristine (Standard); NSC-67574 (Standard); 22-Oxovincaleukoblastine (Standard)
Cat. No.: HY-N0488S
CAS No.: 1246817-10-6
Synonyms: Leurocristine-d3 sulfate; NSC-67574-d3 sulfate; 22-Oxovincaleukoblastine-d3 sulfate
Cat. No.: HY-N0488S2
Synonyms: Leurocristine-d6 sulfate; NSC-67574-d6 sulfate; 22-Oxovincaleukoblastine-d6 sulfate
Cat. No.: HY-W027592
CAS No.: 61-82-5
Cat. No.: HY-W250160
CAS No.: 100403-24-5
Synonyms: Polydeoxyribonucleotide
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Oxiran-2-ylmethanol (Standard) is the analytical standard of Oxiran-2-ylmethanol (Glycidol) (HY-Y1010). This product is intended for research and analytical applications. Oxiran-2-ylmethanol is an ester product. Oxiran-2-ylmethanol induces base pair point mutations in bacterial strains and structural chromosome aberrations in cultured cells. Oxiran-2-ylmethanol forms N-(2,3-dihydroxypropyl)valine hemoglobin adducts. Oxiran-2-ylmethanol acts as an animal carcinogen but does not significantly induce micronucleated immature erythrocytes in animal bone marrow. Oxiran-2-ylmethanol enables anionic polymerization to produce linear poly(glycidol). Oxiran-2-ylmethanol can be used for cancer-related research .
Cat. No.: HY-Y1010S
CAS No.: 1246819-20-4
Synonyms: Glycidol-d5
Cat. No.: HY-W088188
CAS No.: 14024-48-7
Synonyms: Cobalt(II) acetylacetonate
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Co (acac)2 is an organometallic compound with catalytic activity, in which the central cobalt ion is chelated with acetylacetonate ligands. Co (acac)2 can serve as a precursor for thin films and nanomaterials, and is applicable to researches in organic synthesis, materials science, industrial applications, and other fields .
Cat. No.: HY-W110542K
CAS No.: 26570-48-9
Synonyms: PEGDA (MW 1500)
Cat. No.: HY-W250183
CAS No.: 9005-00-9
Synonyms: Polyethylene glycol octadecyl ether (n～10, average Mn～711)
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Polyoxyethylene (10) stearyl ether (Polyethylene glycol octadecyl ether (n~10, average Mn~711)) is a nonionic surfactant. Polyoxyethylene (10) stearyl ether reduces interfacial tension through its amphiphilic structure, stabilizes emulsions via steric hindrance, and forms micelles for solubilization. Polyoxyethylene (10) stearyl ether can serve as a biomaterial or organic compound for life science-related research.
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Cat. No.: HY-100557B
CAS No.: 9004-64-2
Synonyms: Hydroxypropyl Cellulose, Viscosity(1%):150-400mPa.s
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HPC, Viscosity (1%): 150-400 mPa.s (Hydroxypropyl Cellulose, Viscosity (1%): 150-400 mPa.s) is a non-ionic, biocompatible cellulose derivative. HPC, Viscosity (1%): 150-400 mPa.s serves as a thickener or gelling agent, lubricant, and emulsion stabilizer, and is also used in the preparation of capsules and films .
Cat. No.: HY-100557C
CAS No.: 9004-64-2
Synonyms: Hydroxypropyl Cellulose, Viscosity(1%):4000-6500mPa.s
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HPC, Viscosity(1%):4000-6500mPa.s (Hydroxypropyl Cellulose, Viscosity (1%): 150-400 mPa.s) is a non-ionic, biocompatible cellulose derivative. HPC, Viscosity(1%):4000-6500mPa.s serves as a thickener or gelling agent, lubricant, and emulsion stabilizer, and is also used in the preparation of capsules and films .
Cat. No.: HY-183762
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Tubulin-IN-68 is a tubulin inhibitor with an IC50 of 19.3 μM. Tubulin-IN-68 exhibits antiproliferative activity against human cancer cells. Tubulin-IN-68 induces G2/M phase cell cycle arrest. Tubulin-IN-68 induces apoptosis. Tubulin-IN-68 can be used in the research of colorectal cancer, hepatocellular carcinoma, breast cancer, and T-cell leukemia .
Cat. No.: HY-103078R
CAS No.: 5496-35-5
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I-XW-053 (Standard) is the analytical standard of I-XW-053 (HY-103078). This product is intended for research and analytical applications. I-XW-053 is a specific anti-HIV-1 capsid inhibitor (IC50=164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD (Kd=66.3 μM), I-XW-053 disrupts capsid function and reduces polymerization levels. I-XW-053 effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 can be widely used in studies related to HIV-1 infection .
Cat. No.: HY-115364R
CAS No.: 14255-87-9
Synonyms: SKF 29044 (Standard)
Parbendazole (Standard) (SKF 29044 (Standard)) is the analytical standard of Parbendazole (HY-115364). This product is intended for research and analytical applications. Parbendazole (SKF‑29044) is an orally active benzimidazole carbamate compound with multiple biological activities. Parbendazole binds to free tubulin and inhibits microtubule polymerization; it also activates the JNK/c‑Jun signaling axis and upregulates the expression of the downstream axonal repulsion factor Sema3A. Parbendazole upregulates KAL-1 mRNA expression, reduces nerve growth factor levels, and promotes the terminal differentiation of normal human epidermal keratinocytes. Parbendazole induces apoptosis in differentiated acute myeloid leukemia monocytes and exerts antileukemic activity in a mouse xenograft model of acute myeloid leukemia. Parbendazole exhibits broad-spectrum anthelmintic activity against various animal nematodes. Parbendazole is used in research related to acute myeloid leukemia and parasitic infections .
Cat. No.: HY-115364S
CAS No.: 1613439-58-9
Synonyms: SKF 2904-d3
Parbendazole-d3 (SKF 2904-d3) is the deuterated-labeled Parbendazole (HY-115364). Parbendazole (SKF‑29044) is an orally active benzimidazole carbamate compound with multiple biological activities. Parbendazole binds to free tubulin and inhibits microtubule polymerization; it also activates the JNK/c‑Jun signaling axis and upregulates the expression of the downstream axonal repulsion factor Sema3A. Parbendazole upregulates KAL-1 mRNA expression, reduces nerve growth factor levels, and promotes the terminal differentiation of normal human epidermal keratinocytes. Parbendazole induces apoptosis in differentiated acute myeloid leukemia monocytes and exerts antileukemic activity in a mouse xenograft model of acute myeloid leukemia. Parbendazole exhibits broad-spectrum anthelmintic activity against various animal nematodes. Parbendazole is used in research related to acute myeloid leukemia and parasitic infections .
Cat. No.: HY-120339
CAS No.: 1578247-29-6
STK899704 is a tubulin polymerization inhibitor. STK899704 exhibits broad-spectrum inhibitory activity against various cancer cell lines with IC50 values ranging from 0.2 to 1.0 μM. STK899704 disrupts the mitotic spindle structure, inducing G2/M phase cell cycle arrest. STK899704 inhibits the migration ability of HT29 cells by downregulating the FAK-MEK-ERK signaling pathway, thereby suppressing the expression and activity of MMP-2 and MMP-9. STK899704 activates caspase-3/7/8/9, leading to PARP cleavage and inducing apoptosis. STK899704 induces cellular senescence through the p53 pathway. STK899704 can be used in research on skin cancer, lung cancer, colon cancer, and other cancers .
Cat. No.: HY-B0426A
CAS No.: 140462-76-6
Synonyms: ALO4943A; KW4679
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Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 + and CD8 + T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
