195 Results for "

quantify

" in MedChemExpress (MCE) Product Catalog:
Products (195)

195 Results for "quantify" in MCE Product Catalog:

Cat. No.: HY-W019721R
CAS No.: 63775-96-2
Cyclosporin D (Standard) is the analytical standard of Cyclosporin D. This product is intended for research and analytical applications. Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
loading...
    loading...
Cat. No.: HY-137815
CAS No.: 18918-31-5
Purity:  98.44%
4-Nitrophenyl α-L-rhamnopyranoside is a commonly used substrate in various biochemical assays to measure the activity of enzymes that hydrolyze rhamnose, such as α-L-rhamnosidase. 4-Nitrophenyl α-L-rhamnopyranoside has unique chemical properties that allow it to be hydrolyzed by these enzymes to form a yellow product called p-nitrophenol. This makes it a useful tool for detecting and quantifying rhamnohydrolase activity in biological samples or microbial cultures.
loading...
    loading...
Cat. No.: HY-169491
CAS No.: 1224691-12-6
Target:  

Fluorescent Dye

Research Areas:  

Metabolic Disease

Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively .
loading...
    loading...
Cat. No.: HY-183401
CAS No.: 137593-43-2
Synonyms: GS-Mal
Target:  

Apoptosis

Research Areas:  

Cancer

Glutathione maleimide (GS-Mal) is a glutathione depletor and oxidative stress inducer that reduces intracellular GSH levels in cancer cells and induces apoptosis. Glutathione maleimide can selectively extract and quantify GSH from complex biological samples, and the polymeric micelles prepared from it also inhibit the growth of cancer cells in a concentration-dependent manner. Glutathione maleimide has broad applications in breast cancer and related fields .
loading...
    loading...
Cat. No.: HY-W013168
CAS No.: 1492-30-4
Synonyms: 4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate; pNpp
Target:  

Lipase

Research Areas:  

Others

4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate) is a chromogenic substrate for lipases and esterases. Upon enzymatic hydrolysis, 4-Nitrophenyl palmitate releases p-nitrophenol, which can be quantified by colorimetric detection at 410 nm as a measure of enzymatic activity. 4-Nitrophenyl palmitate is used to characterize the activity of various bacterial and mammalian enzymes, including those from Burkholderia and porcine pancreatic lipase .
loading...
    loading...
Cat. No.: HY-P3098
CAS No.: 256394-94-2
Target:  

MMP

Research Areas:  

Others

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .
loading...
    loading...
Cat. No.: HY-P4401A
Target:  

Fluorescent Dye Caspase

Research Areas:  

Others

Z-VEID-AFC TFA is the trifluoroacetate salt of Z-VEID-AFC (HY-P4401). Z-VEID-AFC TFA is a fluorescent substrate for caspase-6. When Z-VEID-AFC TFA is cleaved by caspase-6, 7-amino-4-trifluoromethylcoumarin (AFC) is released, and its fluorescence can be used to quantify caspase-6 activity (Ex/Em: 400/505 nm) .
loading...
    loading...
Cat. No.: HY-W110896
CAS No.: 2411-89-4
Synonyms: Phthalein Purple
Phthalate complexing agent [Chelation indicator] is a class of organic compounds belonging to the category of chelation indicators. It is commonly used in analytical chemistry to detect and quantify metal ions in aqueous solutions, especially in complexometric titration. Phthalate complexing agent [Chelation indicator] works by forming stable complexes with metal ions, which can then be measured using various spectroscopic or electrochemical techniques. In addition, it also has potential applications in wastewater treatment and environmental monitoring.
loading...
    loading...
Cat. No.: HY-W751238
CAS No.: 931418-92-7
Synonyms: DMMB
Dimethyl methylene blue zinc chloride double salt (DMMB) is a cationic dye. Dimethyl methylene blue zinc chloride double salt competitively binds to the active site of the PANI-Benz-Ag nanocomposite with endotoxin, releasing DMMB and increasing the fluorescence intensity. Dimethyl methylene blue zinc chloride double salt can be used as a fluorescent probe for the detection of bacteria (such as E. Coli) endotoxin . Dimethyl methylene blue zinc chloride double salt can be used for the quantification of sulfated glycosaminoglycans .
loading...
    loading...
Cat. No.: HY-D3010
VF dsDNA Green Dye is a fluorescent dye for detecting and quantifying double-stranded DNA (dsDNA). VF dsDNA Green Dye fluoresces only when bound to dsDNA, and the fluorescence intensity is proportional to the DNA concentration. VF dsDNA Green Dye does not fluoresce when bound to ssDNA, RNA, or free nucleotides. VF dsDNA Green Dye can detect dsDNA within the range of 25 pg/mL to 1000 ng/mL (Ex/Em = 480/520 nm).
loading...
    loading...
Cat. No.: HY-DY1041
CAS No.: 147963-22-2
CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
Solvent and concentration: DMSO: 10 mM
loading...
    loading...
Cat. No.: HY-DY1103
CAS No.: 60842-46-8
FITC-Dextran (MW 70000) (solution) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments.
Solvent and concentration: ddH2O: 1 mM
loading...
    loading...
Cat. No.: HY-P10943
CAS No.: 3051946-11-0
Target:  

Fluorescent Dye

Research Areas:  

Inflammation/Immunology Cancer

APO-15 is a phosphatidylserine-binding fluorescent probe and apoptosis imaging reagent. APO-15 exhibits high chemical stability under proteolytic and oxidative conditions, enables quantification and imaging of drug-induced apoptosis in preclinical mouse models, and is applicable to fixed tissue samples and multiple in vivo administration routes (Ex = 488 nm; Em = 525 nm). APO-15 can be used in studies related to acute lung injury and breast cancer .
loading...
    loading...
Cat. No.: HY-W778830
CAS No.: 1246355-58-7
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

Bodipy C12-ceramide (B12Cer) is a fluorescently tagged form of C12-Ceramide (HY-100353) that displays excitation/emission maxima of 505/540 nm, respectively. Bodipy C12-ceramide is formed when acid sphingomyelinase hydrolyzes BODIPY-C12 sphingomyelin in vitro and has been used to quantify acid sphingomyelinase activity in plasma with Niemann-Pick disease .
loading...
    loading...
Cat. No.: HY-116768
CAS No.: 21870-97-3
Synonyms: 10E,12Z-CLA Methyl ester; Methyl 10(E),12(Z)-octadecadienoate methyl ester; (10E,12Z)-SFE 19:2
Research Areas:  

Others

10(E),12(Z)-Conjugated linoleic acid methyl ester (10E,12Z-CLA Methyl ester; Methyl 10(E),12(Z)-octadecadienoate methyl ester; SFE 19:2) is derivative of conjugated linoleic acid. 10(E),12(Z)-Conjugated linoleic acid methyl ester is utilized in the quantification of 10(E),12(Z)-conjugated linoleic acid .
loading...
    loading...
Cat. No.: HY-137249
CAS No.: 95079-19-9
Purity:  98.32%
Resorufin-β-D-galactopyranoside is a commonly used substrate in various biochemical assays to measure the activity of β-galactosidase, an important enzyme involved in lactose metabolism and regulation of gene expression. Resorufin-β-D-galactopyranoside has unique chemical properties and can be hydrolyzed by β-galactosidase to form a red fluorescent product called resorufin. This makes it a useful tool for detecting and quantifying β-galactosidase activity in biological samples such as bacteria or mammalian cells.
loading...
    loading...
Cat. No.: HY-137855
CAS No.: 15220-11-8
Purity:  99.29%
4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.
loading...
    loading...
Cat. No.: HY-158616
CAS No.: 1286479-53-5
4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one (compound 2f) is a selenol fluorescent probe designed based on a nucleophilic aromatic substitution mechanism. It can selectively recognize selenols in neutral aqueous solution without significant interference from biological thiols, amines or alcohols. It can be used to quantify the selenium content in selenoenzymes and to image the activity of endogenous selenols in living cells.
loading...
    loading...
Cat. No.: HY-D2341
CAS No.: 3055969-34-8
6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .
loading...
    loading...
Cat. No.: HY-W127380
CAS No.: 146797-82-2
Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.
loading...
    loading...