162 Results for "

Pde5

" in MedChemExpress (MCE) Product Catalog:
Products (162)

162 Results for "Pde5" in MCE Product Catalog:

Moracin M (Standard)
Moracin M (Standard)
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Cat. No.: HY-122942R
CAS No.: 56317-21-6
Category:  

Moraceae Extract Phenols Polyphenols Plants Endogenous metabolite Morus alba Linn.

Target:  

Phosphodiesterase (PDE) Endogenous Metabolite NF-κB Autophagy Reference Standards

Moracin M (Standard) is the analytical standard of Moracin M. This product is intended for research and analytical applications. Moracin M is a phenolic component that can be isolated from Mori Cortex, is a potent phosphodiesterase-4 (PDE4) inhibitor with IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. Moracin M has anti-inflammatory activity .
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Sequoiaflavone
Sequoiaflavone
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Cat. No.: HY-119416
CAS No.: 21763-71-3
Category:  

Flavonoids Taxaceae Extract Plants Biflavones Taxus baccata L.

Target:  

Cytochrome P450 Amyloid-β Phosphodiesterase (PDE) Fungal

Sequoiaflavone is a biflavonoid compound with multiple activities. Sequoiaflavone suppresses hepatic CYP1A1/(7-Ethoxycoumarin O-deethylase) ECOD, prevents Aβ1-42 fibrillization (IC50 = 0.29 μM) and disaggregates amyloid fibrils (EC50 = 2.04 μM), inhibits Alternaria alternata and inhibits human recombinant PDE5A1 overexpressed in COS-7 cells (IC50 = 19.9 μM) to exert NO-independent vasodilation. Sequoiaflavone can be used in Alzheimer's disease, peripheral circulatory disorder, and antifungal research .
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