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(E)-Hex-2-en-1-ol

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製品番号 製品名 Target 研究分野 構造式
  • HY-131904
    POMHEX
    3 Publications Verification

    		 Enolase Apoptosis Metabolic Disease Cancer
    POMHEX, a racemic mixture and a cell-permeable pivaloyloxymethyl (POM) proagent of HEX, is a potent, ENO2-specific inhibitor of enolase. POMHEX exhibits low-nanomolar potency against ENO1-deleted cells in vitro and is capable of eradicating ENO1-deleted xenografted tumours in vivo. POMHEX is a potent glycolysis inhibitor .
    POMHEX
  • HY-136205
    IA-Alkyne
    4 Publications Verification

    Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide

    		 TRP Channel Infection Inflammation/Immunology
    IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    IA-Alkyne
  • HY-131904A
    Hex

    		Enolase Parasite Infection Cancer
    Hex is an enolase inhibitor and antimalarial agent with Ki values of 74.4 nM and 269.4 nM for ENO2 and ENO1, respectively. Hex is a NfENO and TbENO inhibitor with IC50s value of 0.14 μM and 2.1 μM, respectively. Hex has antimalarial activity against Plasmodium falciparum 3D7, Naegleria fowleri trophozoites and Plasmodium berghei ANKA strain. Hex has anti-tumor effects against intracranial tumors .
    Hex
  • HY-W010532
    trans-3-Hexenoic acid

    (E)-Hex-3-enoic acid

    		 Biochemical Assay Reagents Others
    (E)-Hex-3-enoic acid is an unsaturated organic compound. It is commonly used as a fragrance ingredient in a variety of products, including food, beverages, and personal care products, and it can also be used as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. In addition, (E)-Hex- 3-enoic acid has been investigated for its potential use as a biobased solvent due to its low toxicity and biodegradability, as well as its potential antibacterial and antifungal properties, which may make it useful for developing new Antibacterial agents.
    trans-3-Hexenoic acid
  • HY-Y0925
    5-Hexynoic acid

    Hex-5-ynoic acid

    		 Drug Intermediate PROTAC Linkers Others
    5-Hexynoic acid (Hex-5-ynoic acid) is an alkynoic acid. 5-Hexynoic acid serves as a drug intermediate for the synthesis of 3-alkoxy-2-cyclohexenone .
    5-Hexynoic acid
  • HY-W015936
    (E)-Hex-2-en-1-ol

    trans-Hex-2-en-1-ol

    		 Environmental Pollutants Biochemical Assay Reagents Others
    (E)-Hex-2-en-1-ol belongs to the class of unsaturated alcohols consisting of a six-carbon chain with a double bond between carbon atoms 2 and 3 and a hydroxyl group attached to carbon atom 1. The compound has a grassy or herbaceous smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products and as a starting material for the synthesis of other organic compounds. Furthermore, (E)-hex-2-en-1-ol can be used as a solvent or reagent in various chemical reactions.
    (E)-Hex-2-en-1-ol
  • HY-N2426
    Clerodendrin

    		Interleukin Related Inflammation/Immunology
    Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor .
    Clerodendrin
  • HY-104050
    M-31850
    2 Publications Verification

    		 Glycosidase Metabolic Disease
    M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM .
    M-31850
  • HY-114289
    6-HEX
    1 Publications Verification

    		 Fluorescent Dye Others
    6-HEX is one kind of light base group, the wave length is 532 nm, the wave length is 556 nm. 6-HEX can be used to record nucleic acid sequences and design optical materials. 6-HEX can be used to record nucleic acids at 543 nm radiation, and at 550 nm and 650 nm radiation (5 nm radiation), it can be used to directly locate the base of the cell group .
    6-HEX
  • HY-W015943
    Hex-5-yn-1-ol

    5-Hexyn-1-ol

    		 PROTAC Linkers Cancer
    Hex-5-yn-1-ol (5-Hexyn-1-ol) is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-5-yn-1-ol
  • HY-34643
    6-Heptynoic acid

    Hept-6-ynoic acid

    		 Drug Intermediate Others
    Hexanoylic acid (Hex-6-ynoic acid) is a drug intermediate. Hexanoylic acid can be functionalized by esterification reaction to paclitaxel (HY-B0015), enabling it to undergo an efficient ring addition reaction with β-cyclodextrin, thereby enhancing its water solubility, stability and targeting properties .
    6-Heptynoic acid
  • HY-156586
    Egalognastat

    ASN90

    		 OGA Tau Protein Neurological Disease
    Egalognastat (ASN90) is a selective, brain-penetrant and orally active O-GlcNAcase (OGA) enzyme inhibitor with an IC50 value of 10.2 nM. Egalognastat increases O-GlcNAcylation of intracellular proteins like tau and α-synuclein, preventing their aggregation and toxicity. Egalognastat does not inhibit hexosaminidase (Hex). Egalognastat can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies (e.g., Alzheimer’s disease and Parkinson’s disease) .
    Egalognastat
  • HY-P3441A
    3BP-4089 TFA

    		FAP Cancer
    3BP-4089 TFA is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 TFA is often conjugated with radionuclides for tumor diagnosis and research .
    3BP-4089 TFA
  • HY-W050829
    tert-Butyl hex-5-yn-1-ylcarbamate

    		PROTAC Linkers Cancer
    tert-Butyl hex-5-yn-1-ylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
    tert-Butyl hex-5-yn-1-ylcarbamate
  • HY-W010531
    trans-Hex-2-enoic acid

    trans-2-Hexenoic acid

    		 Biochemical Assay Reagents Others
    trans-Hex-2-enoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    trans-Hex-2-enoic acid
  • HY-161242A
    CBI1 formic

    		Bcl-2 Family Cancer
    CBI1 formic is a covalent BAX inhibitor. CBI1 formic selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 formic blocks t-2-hex lipidation and oligomerization of BAX. CBI1 formic inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
    CBI1 formic
  • HY-P3441
    3BP-4089

    		FAP Cancer
    3BP-4089 is a highly efficient fibroblast activation protein (FAP) targeting peptide. 3BP-4089 is often conjugated with radionuclides for tumor diagnosis and research .
    3BP-4089
  • HY-D0828
    3,6-Dichlorotrimellitic acid

    		DNA Stain MOFs Others
    3,6-Dichlorotrimellitic acid is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
    3,6-Dichlorotrimellitic acid
  • HY-D0829
    3,6-Dichlorotrimellitic anhydride

    		DNA Stain Others
    3,6-Dichlorotrimellitic anhydride is the key precursor that is used for preparing a variety of dichlorinated fluoresceins and rhodamines such as TET and HEX.
    3,6-Dichlorotrimellitic anhydride
  • HY-D1891
    6-HEX, SE

    		Fluorescent Dye Others
    6-HEX, SE is a derivative of 6-HEX that is widely used in nucleic acid sequencing .
    6-HEX, SE
  • HY-W130918A
    Hex-3-enedinitrile

    		PROTAC Linkers Cancer
    Hex-3-enedinitrile is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-3-enedinitrile
  • HY-W453529
    Ethyl hex-5-ynoate

    		PROTAC Linkers Cancer
    Ethyl hex-5-ynoate is a PROTAC linker that can be used in the synthesis of PROTACs.
    Ethyl hex-5-ynoate
  • HY-W023192
    Hex-5-yn-1-amine hydrochloride

    		PROTAC Linkers Cancer
    Hex-5-yn-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-5-yn-1-amine hydrochloride
  • HY-W411604
    tert-Butyl hex-5-ynoate

    		PROTAC Linkers Cancer
    tert-Butyl hex-5-ynoate is the linker that can be used for PROTAC synthesis of PROTAC cGAS degrader-1 (HY-172208) .
    tert-Butyl hex-5-ynoate
  • HY-W783829
    (2E)-Hexenoyl-CoA

    Hex-2-trans-enoyl-CoA

    		 Endogenous Metabolite Metabolic Disease
    (2E)-Hexenoyl-CoA (Hex-2-trans-enoyl-CoA) is an intermediate in fatty acid metabolism. (2E)-Hexenoyl-CoA undergoes reductive carboxylation to yield butylmalonyl-CoA .
    (2E)-Hexenoyl-CoA
  • HY-CE00457
    (Z)-Hex-3-enoyl-CoA

    (Z)-Hex-3-enoyl-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    (Z)-Hex-3-enoyl-CoA ((Z)-Hex-3-enoyl-coenzyme A) is a fatty acyl-CoA.
    (Z)-Hex-3-enoyl-CoA
  • HY-D1893
    HEX azide, 6-isomer

    		Fluorescent Dye Others
    HEX azide, 6-isomer, a derivate of fluorescent dye hexachlorofluorescein (HEX), can be used for labeling oligonucleotides .
    HEX azide, 6-isomer
  • HY-163011
    Dicamba-hex-5-ynoic acid

    		Biochemical Assay Reagents Others
    Dicamba-hex-5-ynoic acid is a hapten that can be coupled with Ovalbumin (OVA). Dicamba-hex-5-ynoic acid can be used in dicamba analysis .
    Dicamba-hex-5-ynoic acid
  • HY-164869
    1-Hex-GlcNAlk

    		Biochemical Assay Reagents Others
    1-Hex-GlcNAlk is a metabolic chemical reporter (MCR) utilized in glycosylation research. 1-Hex-GlcNAlk exhibits robust labeling over background with negligible amounts of nonspecific chemical labeling in cell lysates .
    1-Hex-GlcNAlk
  • HY-W570685
    Hex-5-yn-1-yl 4-methylbenzenesulfonate

    		PROTAC Linkers Cancer
    Hex-5-yn-1-yl 4-methylbenzenesulfonate is a PROTAC linker that can be used in the synthesis of PROTACs.
    Hex-5-yn-1-yl 4-methylbenzenesulfonate
  • HY-W344269
    Tert-butyl(hex-5-yn-1-yloxy)dimethylsilane

    		PROTAC Linkers Cancer
    Tert-butyl(hex-5-yn-1-yloxy)dimethylsilane is a PROTAC linker that can be used in the synthesis of PROTACs.
    Tert-butyl(hex-5-yn-1-yloxy)dimethylsilane
  • HY-W008836S
    (E)-Hex-3-en-1-ol-d2

    trans-3-Hexen-1-ol-d2

    		 Isotope-Labeled Compounds Others
    (E)-Hex-3-en-1-ol-d2 is deuterated labeled (E)-Hex-3-en-1-ol.
    (E)-Hex-3-en-1-ol-d2
  • HY-W436499
    1,5-Anhydro-2-deoxy-D-lyxo-hex-1-enitol tribenzoate

    		Biochemical Assay Reagents Others
    1,5-Anhydro-2-deoxy-D-lyxo-hex-1-enitol tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    1,5-Anhydro-2-deoxy-D-lyxo-hex-1-enitol tribenzoate
  • HY-W698362
    α-D-threo-Hex-2-enopyranoside,methyl 2,3-dideoxy-4,6-diacetate

    		Biochemical Assay Reagents Others
    α-D-threo-Hex-2-enopyranoside,methyl 2,3-dideoxy-4,6-diacetate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    α-D-threo-Hex-2-enopyranoside,methyl 2,3-dideoxy-4,6-diacetate
  • HY-161242
    CBI1

    		Bcl-2 Family Cancer
    CBI1 is a covalent BAX inhibitor. CBI1 selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 blocks t-2-hex lipidation and oligomerization of BAX. CBI1 inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .
    CBI1
  • HY-147107
    OfHex1-IN-2

    		Insecticide Others
    OfHex1-IN-2 (compound I-79) is a potent β-N-acetylhexosaminidase OfHex1 inhibitor. OfHex1-IN-2 can be used in control of insect .
    OfHex1-IN-2
  • HY-RS06159
    HHEX Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HHEX Human Pre-designed siRNA Set A contains three designed siRNAs for HHEX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HHEX Human Pre-designed siRNA Set A
    HHEX Human Pre-designed siRNA Set A
  • HY-D2737
    DMT-BH2 amidite

    BHQ-2 DMT amidite

    		 Fluorescent Dye Others
    DMT-BH2 amidite (BHQ-2 DMT amidite) is a black quencher dye for the synthesis of dual-labeled oligonucleotide probes for qPCR bearing 5'-quencher. This quencher is ideal for HEX, JOE, ROX, Cyanine5, and other dyes with emissions in the orange and red parts of the spectrum.
    DMT-BH2 amidite
  • HY-W145544
    6-O-(Triisopropylsilyl)-D-glucal

    1,5-Anhydro-2-deoxy-6-O-(triisopropylsilyl)-D-arabino-Hex-1-enitol

    		 Biochemical Assay Reagents Others
    6-O-(Triisopropylsilyl)-D-glucal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    6-O-(Triisopropylsilyl)-D-glucal
  • HY-130510
    6-HEX dipivaloate

    		Fluorescent Dye Others
    6-HEX dipivaloate is an amino-bindable fluorescent probe that can be used to label peptides and oligonucleotides. 6-HEX dipivaloate is widely used in nucleic acid sequencing and related research .
    6-HEX dipivaloate
  • HY-116295
    MRS2690

    		P2Y Receptor p38 MAPK Calcium Channel Cardiovascular Disease
    MRS2690 is a selective P2Y14 receptor agonist. MRS2690 inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690can be used for ischemic heart disease .
    MRS2690
  • HY-116295A
    MRS2690 disodium

    		P2Y Receptor p38 MAPK Calcium Channel Cardiovascular Disease
    MRS2690 disodium is a selective P2Y14 receptor agonist. MRS2690 disodium inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 disodium induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690 disodium can be used for ischemic heart disease .
    MRS2690 disodium
  • HY-W822795
    Benzyl hex-5-yn-1-ylcarbamate

    		PROTAC Linkers Cancer
    Benzyl hex-5-yn-1-ylcarbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
    Benzyl hex-5-yn-1-ylcarbamate
  • HY-W840196
    Hex-5-ynehydrazide

    		Biochemical Assay Reagents Others
    Hex-5-ynehydrazide is a bifunctional linker reagent with a terminal hydrazide group and a propargyl group. The hydrazide group can react with an aldehyde to form a semi-permanent hydrozone bond. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
    Hex-5-ynehydrazide
  • HY-201158
    2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite

    5'-Hexynyl phosphoramidite

    		 Phosphoramidites
    2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    2-Cyanoethyl hex-5-yn-1-yl diisopropylphosphoramidite
  • HY-172218
    Lenalidomide-hex-5-ynoic acid

    		E3 Ligase Ligand-Linker Conjugates Others
    Lenalidomide-hex-5-ynoic acid is a conjugate of E3 ligase ligand and linker, and can be used to synthesize PROTACs, such as PROTAC cGAS degrader-1 (HY-172208) .
    Lenalidomide-hex-5-ynoic acid
  • HY-D2739
    SIMA phosphoramidite, 6-isomer

    		Fluorescent Dye Others
    SIMA phosphoramidite, 6-isomer is a xanthene dye with spectral characteristics similar to those of HEX but with a higher quantum yield. SIMA has higher stability during deprotection under alkaline conditions.
    SIMA phosphoramidite, 6-isomer
  • HY-108241A
    Galacto-PUGNAc

    		Glycosidase Neurological Disease
    Galacto-PUGNAc is a selective competitive inhibitor of lysosomal β-hexosaminidases (HEX), with Ki values of 51 and 18 nM, for hHEXA and hHEXB, respectively. Galacto-PUGNAc elevates GM2 ganglioside levels in neuroblastoma cells. Galacto-PUGNAc can be used for the research of neurodegenerative disorders .
    Galacto-PUGNAc
  • HY-P2835A
    Alginate lyase, Sphingomonas sp.

    		Biochemical Assay Reagents Others
    Alginate lyase, Sphingomonas sp. (EC 4.2.2.3) is an enzyme that catalyzes the chemical reaction:Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. Alginate lyase, Sphingomonas sp. (EC 4.2.2.3) belongs to the family of lyases, participates in fructose and mannose metabolism.
    Alginate lyase, Sphingomonas sp.
  • HY-104050R
    M-31850 (Standard)

    		Glycosidase Reference Standards Metabolic Disease
    M-31850 (Standard) is the analytical standard of M-31850 (HY-104050). This product is intended for research and analytical applications. M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM .
    M-31850 (Standard)

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