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Results for "

αvβ1 integrin-IN-1

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-100445A
    αvβ1 integrin-IN-1 TFA
    5+ Cited Publications

    		 Integrin Cardiovascular Disease Cancer
    αvβ1 integrin-IN-1 TFA (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects .
    αvβ1 integrin-IN-1 TFA
  • HY-100445
    αvβ1 integrin-IN-1
    5+ Cited Publications

    		 Integrin Cardiovascular Disease Cancer
    αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects .
    αvβ1 integrin-IN-1
  • HY-B0665
    Fibrin

    		Integrin Cardiovascular Disease
    Fibrin is an insoluble protein found in blood that is produced in response to bleeding. As the main component of blood clots, fibrin functions in blood coagulation. Fibrin binds to the integrins ICAM-1, VE-cadherin, αIIbβ3, αMβ2, αvβ3 and α5β1. Fibrin is used in research related to chronic wounds .
    Fibrin
  • HY-156521
    αvβ1 integrin-IN-2

    		Integrin Others
    αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM，and 33 nM，respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ，，IC50s of 380 nM (ανβ3)，280 nM (ανβ5)，230 nM (ανβ6)，87 nM (ανβ8)，respectively，in SPRA assay .
    αvβ1 integrin-IN-2
  • HY-180057
    α5β1 integrin-IN-1

    		Integrin Inflammation/Immunology
    α5β1 integrin-IN-1 (compound 65) is a potent and selective α5β1 integrin inhibitor with a pIC50 of 9.4. α5β1 integrin-IN-1 displays >10000-fold selectivity for α5β1 over αVβ3 (pIC50 = 5.5). α5β1 integrin-IN-1 reduces airway smooth muscle (ASM) tension through the disruption of cellular tethering. α5β1 integrin-IN-1 exhibits excellent inhalation pharmacokinetics in rodent. α5β1 integrin-IN-1 can be used for asthma research .
    α5β1 integrin-IN-1

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