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Results for "

β-lactam antibiotic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (110) Apoptosis (5) Aurora Kinase (8) Bacterial (120) Beta-lactamase (26) Biochemical Assay Reagents (7) Cytochrome P450 (1) DNA/RNA Synthesis (3) Drug Intermediate (5) Drug Metabolite (3) Endogenous Metabolite (1) Environmental Pollutants (1) Estrogen Receptor/ERR (1) Fungal (1) GSK-3 (6) Histamine Receptor (3) HSP (3) Interleukin Related (1) Isotope-Labeled Compounds (9) Orthopoxvirus (3) p38 MAPK (1) Parasite (3) Penicillin-binding protein (PBP) (15) PKC (1) Reference Standards (33) TNF Receptor (1)
By Research Areas:	Cancer (28) Cardiovascular Disease (3) Endocrinology (2) Infection (135) Inflammation/Immunology (15) Metabolic Disease (2) Neurological Disease (1)
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149

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Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0522

Ampicillin Maximum Cited Publications 80 Publications Verification D-(-)-α-Aminobenzylpenicillin	Bacterial Antibiotic	Infection
Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

HY-B0522A

Ampicillin sodium Maximum Cited Publications 80 Publications Verification D-(-)-α-Aminobenzylpenicillin sodium salt	Bacterial Antibiotic	Infection
Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B0974

Methicillin sodium salt 5+ Cited Publications Meticillin sodium	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Methicillin sodium salt (Meticillin sodium) is a β-lactam, semi-synthetic antibiotic related to penicillin antibiotic. Methicillin sodium salt inhibits penicillin-binding proteins involved in the synthesis of peptidoglycan. Methicillin sodium salt inhibits S. aureus with a MIC value of 2.1 μg/mL. Methicillin sodium salt can be used for the research of inflammation .

HY-B1463

Penicillin G sodium salt 20+ Cited Publications Benzylpenicillin sodium salt	Beta-lactamase Bacterial Antibiotic	Infection
Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-108913

Nitrocefin 2 Publications Verification	Beta-lactamase Antibiotic Bacterial	Infection
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .

HY-B1923

Piperacillin 10+ Cited Publications Pipracil	Antibiotic Bacterial Beta-lactamase Penicillin-binding protein (PBP)	Infection Cancer
Piperacillin is a semisynthetic broad-spectrum **β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins**. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-13625

Ertapenem sodium 10+ Cited Publications L-749345; MK-826	Bacterial Antibiotic	Infection Cancer
Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .

HY-A0269

Mecillinam 4 Publications Verification Amdinocillin; FL 1060	Bacterial Antibiotic	Infection
Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .

HY-B1286

Piperacillin sodium 10+ Cited Publications Sodium piperacillin	Bacterial Antibiotic Penicillin-binding protein (PBP)	Infection Cancer
Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-B0977

Dicloxacillin Sodium hydrate 3 Publications Verification Dicloxacillin sodium salt monohydrate	Bacterial Antibiotic	Infection Inflammation/Immunology
Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus .

HY-121329

Carumonam AMA-1080; Ro 17-2301	Penicillin-binding protein (PBP) Antibiotic Bacterial	Infection
Carumonam (AMA-1080; Ro 17-2301) is a sulfonated monocyclic β-Lactam *Antibiotic, targeting to penicillin-binding protein (PBP). Carumonam exerts highly activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while it weakly and even inactively inhibits Streptococcus pneumoniae* and Staphylococcus aureus. Carumonam is resistant to beta-lactamase-mediated hydrolysis .

HY-B0712A

Ceftriaxone sodium hydrate 15+ Cited Publications Ro 13-9904 sodium hydrate	Bacterial Antibiotic GSK-3 Aurora Kinase	Infection Cancer
Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .

HY-147349

Pilabactam sodium ANT3310 sodium	Beta-lactamase Bacterial	Infection
Pilabactam (ANT3310) sodium is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC₅₀ values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). Pilabactam sodium potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). Pilabactam sodium can be used in the research of bacterial infection .

HY-W013549

6-Aminopenicillanic acid 6-APA	Drug Metabolite Bacterial	Infection Inflammation/Immunology
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-B0529A

Azlocillin sodium salt 1 Publications Verification Sodium azlocillin	Bacterial Parasite Antibiotic	Infection
Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam *antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite* Plasmodium falciparum .

HY-B0186B

Cefoselis sulfate FK-037	Bacterial Antibiotic	Infection
Cefoselis sulfate (FK-037), the fourth gen-eration of cephalosporin, is a β-lactam *antibiotic*. Cefoselis sulfate exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis sulfate penetrates the blood-brain barrier .

HY-B1459

Dicloxacillin sodium 3 Publications Verification	Beta-lactamase Bacterial Antibiotic	Infection
Dicloxacillin sodium is a **β-lactam antibiotic** of the penicillin family. Dicloxacillin sodium against Gram-positive bacteria. Dicloxacillin sodium is active against β-lactamase-producing organisms such as Staphylococcus aureus .

HY-B1252

Cefalonium	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-B1923R

Piperacillin (Standard) Pipracil (Standard)	Bacterial Reference Standards Antibiotic Beta-lactamase Penicillin-binding protein (PBP)	Infection Cancer
Piperacillin (Standard) is the analytical standard of Piperacillin. This product is intended for research and analytical applications. Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-B1466

Mezlocillin sodium BAY-f 1353 sodium	Bacterial Antibiotic	Infection
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research .

HY-A0294

Ertapenem MK-0826	Antibiotic Bacterial	Infection Cancer
Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .

HY-A0294A

Ertapenem disodium 10+ Cited Publications MK-0826 disodium	Bacterial Antibiotic	Infection Cancer
Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .

HY-13625R

Ertapenem sodium (Standard) L-749345 (Standard); MK-826 (Standard)	Reference Standards Bacterial Antibiotic	Infection Cancer
Ertapenem sodium (Standard) is the analytical standard of Ertapenem sodium. This product is intended for research and analytical applications. Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract[1][2].

HY-E70318

Penicillin G acylase (Immobilized)	Endogenous Metabolite	Others
Penicillin G acylase (Immobilized) is an immobilized penicillin acylase with improved temperature and pH stability. Penicillin G acylase (Immobilized) has reusable performance and high recovery rates, retaining much of its original activity after 12 cycles. Among them, Penicillin G acylase (Immobilized) can catalyze penicillin G (PG) to generate 6-aminopenicillanic acid (6-APA) and 7-aminodeacetoxycephalosporanic acid, which are key intermediates for β-lactam antibiotics .

HY-121544

Methicillin	Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor	Infection
Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis .

HY-N7120

Penicillin G procaine hydrate PGP hydrate	Bacterial Antibiotic	Infection
Penicillin G Procaine hydrate (PGP hydrate) is a β-lactam antibiotic and sustained-release formulation. Penicillin G procaine (hydrate) hydrolyzes in vivo to release penicillin G and Procaine (HY-B0546), thereby delaying the absorption of penicillin G .

HY-P3519

ACV Tripeptide	Drug Intermediate	Infection
ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics .

HY-W005223

(R)-Tetrahydrofuran-2-carboxylic acid (R)-(+)-Tetrahydrofuran-2-carboxylic acid	Biochemical Assay Reagents Drug Intermediate	Infection
(R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

HY-103645

GW779439X 1 Publications Verification	Bacterial Aurora Kinase Apoptosis	Infection Cancer
GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of β-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway . MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus

HY-34588

D-4-Hydroxyphenylglycine D-(-)-4-Hydroxyphenylglycine; 4-Hydroxy-D-phenylglycine	Antibiotic	Others
D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .

HY-B1286R

Piperacillin sodium (Standard) Sodium piperacillin (Standard)	Reference Standards Bacterial Antibiotic Penicillin-binding protein (PBP)	Infection
Piperacillin (sodium) (Standard) is the analytical standard of Piperacillin (sodium). This product is intended for research and analytical applications. Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .

HY-137927

Benapenem	Antibiotic	Others
Benapenem is a carbapenem-type agent that belongs to the broad-spectrum β-lactam antibiotic class.

HY-16251A

Hetacillin	Bacterial	Infection
Hetacillin is a beta-lactam antibiotic that is part of the aminopenicillin family.

HY-B1459A

Dicloxacillin	Beta-lactamase Bacterial Antibiotic	Infection
Dicloxacillin is a **β-lactam antibiotic** of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .

HY-B1682A

Loracarbef hydrate	Antibiotic Bacterial	Infection
Loracarbef hydrate, a cephalosporin *antibiotic, is an orally active second-generation synthetic beta-lactam* antibiotic of the carbacephem class .

HY-16137

Cefaloglycin Cephaloglycin	Bacterial	Infection
Cefaloglycin (Cephaloglycin) is an orally active nephrotoxic *β-lactam* cephalosporin antibiotic with antibacterial activity. Cefaloglycin is activity against Gram-Positive cocci other than enterococci. Cefaloglycin is toxic to mitochondrial substrate uptake and respiration .

HY-139628

JPD447	Bacterial	Infection Cancer
JPD447, a MAC-0547630 derivative, is a novel class of UppS inhibitor to potentiate β-lactam antibiotics.

HY-B0925S

Oxacillin-13C6 sodium	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Oxacillin- ¹³C₆ (sodium) is the ¹³C₆ labeled Oxacillin (sodium). Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.

HY-W764182

Cephalosporinase,bacillus	Bacterial	Infection
Cephalosporinase, bacillus are enzymes produced by bacillus, inactivated and degrade the ability of the cephalosporin class of antibiotics. Cephalosporins are a class of β-lactam antibiotics that are widely used to study bacterial infections .

HY-B1466A

Mezlocillin BAY-f 1353	Antibiotic Bacterial	Infection
Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research .

HY-147349A

Pilabactam ANT3310	Bacterial Beta-lactamase	Infection
Pilabactam (ANT3310) is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC₅₀ values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). Pilabactam potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). Pilabactam can be used in the research of bacterial infection .

HY-W654157

Dicloxacillin-13C4 sodium hydrate	Antibiotic Isotope-Labeled Compounds Bacterial	Infection
Dicloxacillin- ¹³C₄ sodium hydrate is the ¹³C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to study infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus .

HY-B1682

Loracarbef	Antibiotic Bacterial	Infection
Loracarbef, a cephalosporin *antibiotic, is an orally active second-generation synthetic beta-lactam* antibiotic of the carbacephem class .

HY-B1252A

Cefalonium hydrate	Antibiotic Bacterial	Infection Inflammation/Immunology
Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-121544A

Methicillin sodium hydrate	Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor	Infection
Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .

HY-W013549R

6-Aminopenicillanic acid (Standard) 6-APA (Standard)	Drug Metabolite Reference Standards Bacterial	Infection
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.

HY-A0269S

Mecillinam-d12 Amdinocillin-d₁₂; FL 1060-d₁₂	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Mecillinam-d₁₂ is deuterium labeled Mecillinam. Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .

HY-105113

Cefluprenam	Antibiotic Bacterial	Infection
Cefluprenam is a β-lactam antibiotic with broad-spectrum antibacterial activity .

HY-B0186

Cefoselis	Bacterial Antibiotic	Infection
Cefoselis, the fourth gen-eration of cephalosporin, is a β-lactam *antibiotic*. Cefoselis exhibits good activity against a wide range of Gram-positive and Gram-negative organisms. Cefoselis penetrates the blood-brain barrier .

HY-W140760

Ceftriaxone sodium	Antibiotic	Infection Inflammation/Immunology Cancer
Ceftriaxone sodium is a versatile broad-spectrum β-lactam tertiary cephalosporin antibiotic that exhibits anti-inflammatory, antitumor, antibacterial, and antioxidant properties, and functions as a covalent inhibitor of GSK3β and Aurora B, making it valuable in research related to sepsis and infective endocarditis.

Cat. No.	Product Name

HY-L914

Serine/Threonine Focused Covalent Fragment Library

3,208 compounds

In the research of covalent inhibitors targeting serine and threonine, scientists have found that the nucleophilicity of these hydroxyl groups is significantly enhanced due to the influence of their surrounding environment. This results in higher activity during catalytic reactions. Aspirin, which targets the non-catalytic domain serine (Ser529 in human COX1) of cyclooxygenase, exerts its anti-inflammatory effect through covalent binding. β-lactam antibiotics, which targets the catalytic domain serine of penicillin-binding proteins, interferes with bacterial cell wall synthesis.

Through careful selection, we constructed a structural filter containing over 110 electrophilic groups. By analyzing the electrophilic fragments selected by the structural filter, we removed any molecules with trivial or undesirable structural features. Ultimately, we obtained 3,300 fragment molecules which can target serine and threonine residues and can be used for fragment-based covalent drug discovery.

Cat. No.	Product Name	Type

HY-W005223

(R)-Tetrahydrofuran-2-carboxylic acid (R)-(+)-Tetrahydrofuran-2-carboxylic acid	Biochemical Assay Reagents
(R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

HY-W005223R

(R)-Tetrahydrofuran-2-carboxylic acid (Standard) (R)-(+)-Tetrahydrofuran-2-carboxylic acid (Standard)	Biochemical Assay Reagents
(R)-Tetrahydrofuran-2-carboxylic acid (Standard) is an analytical standard for (R)-Tetrahydrofuran-2-carboxylic acid (HY-W005223). This product is intended for research and analytical applications. (R)-Tetrahydrofuran-2-carboxylic acid is a chiral building block for Faropenem (HY-A0035). Faropenem is a clinically effective non-natural β-lactam antibiotic .

Cat. No.	Product Name	Target	Research Area

HY-P3519

ACV Tripeptide	Drug Intermediate	Infection
ACV Tripeptide, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide can be used for the biosynthesis of β-lactam antibiotics .

HY-P3519A

ACV Tripeptide TFA	Drug Intermediate	Infection
ACV Tripeptide TFA, a tripeptide, is the first dedicated intermediate in the biosynthetic pathway leading to the penicillin and cephalosporin classes of β-lactam natural products in bacteria and fungi. ACV Tripeptide TFA is is synthesized nonribosomally by the ACV synthetase (ACVS) enzyme, which is encoded by the 11 kb The pchAB gene encodes this enzyme. ACV Tripeptide TFA can be used for the biosynthesis of β-lactam antibiotics .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1463

Penicillin G sodium salt 20+ Cited Publications Benzylpenicillin sodium salt	Infection Plant Cell Culture Microorganisms Classification of Application Fields Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Beta-lactam Antibiotics Source Classification	Beta-lactamase Bacterial Antibiotic
Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-B0425A

Novobiocin sodium 10+ Cited Publications Albamycin sodium; Cathomycin sodium	Microorganisms Anti-inflammation/Immunoregulatory Classification of Application Fields Antibiotics Antiviral Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification Cancer	Bacterial Antibiotic Orthopoxvirus Apoptosis DNA/RNA Synthesis HSP
Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity .

HY-W013549

6-Aminopenicillanic acid 6-APA	Human Gut Microbiota Metabolites Endogenous metabolite Source Classification	Drug Metabolite Bacterial
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-W013549R

6-Aminopenicillanic acid (Standard) 6-APA (Standard)	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Drug Metabolite Reference Standards Bacterial
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.

HY-117108

Nocardicin A	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Nocardicin A is a beta-lactam *antibiotic* with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast .

HY-N14895

Chitinovorin A	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Chitinovorin A is a β-lactam antibiotic with a weak inhibitory activity against Gram-negative bacteria .

HY-N14896

Chitinovorin C	Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic Bacterial
Chitinovorin C is a β-lactam antibiotic with a weak inhibitory activity against Gram-negative bacteria .

HY-165272

Antibiotic SF-2132	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Antibiotic
Antibiotic SF-2132 is a peptide antibiotic identified in Nocardiopsis sp., which exhibits inhibitory activity against β-lactam antibiotic-resistant strains, such as Pseudomonas and Escherichia .

HY-N15062

2-Hydroxymethylclavam	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Fungal
2-Hydroxymethylclavam is a β-lactam antibiotic. 2-Hydroxymethylclavam has antifungal activity, especially for plant pathogenic fungi .

HY-B1463R

Penicillin G sodium salt (Standard) Benzylpenicillin sodium salt (Standard)	Structural Classification Plant Cell Culture Microorganisms Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Beta-lactam Antibiotics Source Classification	Beta-lactamase Reference Standards Bacterial Antibiotic
Penicillin G sodium salt (Standard) is the analytical standard of Penicillin G sodium salt. This product is intended for research and analytical applications. Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-121120

Isosulfazecin	Structural Classification Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Antibiotic
Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .

HY-N14919

Olivanic acid	Structural Classification Microorganisms Antibiotics Beta-lactam Antibiotics Source Classification	Beta-lactamase Antibiotic Bacterial
Olivanic acid is a β -lactam antibiotic. Olivanic acid has the effect of anti -Gram-positive bacteria and anti-Gram-negative bacteria. Olivanic acid inhibits β-lactamase .

HY-N19827

Monodesmoside saponin C	Triterpenes Structural Classification Terpenoids Sapindus mukorossi Gaertn. Sapindaceae Plants Source Classification	Biochemical Assay Reagents
Monodesmoside saponin C is an absorption enhancer. Monodesmoside saponin C promotes the absorption of poorly absorbable β-lactam antibiotics in the small intestine and rectum of rats. Monodesmoside saponin C has the ability to chelate Ca ²⁺. The absorption-enhancing activity of Monodesmoside saponin C is inhibited by coexisting Ca ²⁺ ions. Monodesmoside saponin C can be used in studies on absorption enhancement of β-lactam antibiotics .

Cat. No.	Product Name	Chemical Structure

HY-B0522S

Ampicillin-d5
Ampicillin-d₅ is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-B0129S

Aztreonam-d6
Aztreonam-d₆ is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-B0925S

Oxacillin-13C6 sodium
Oxacillin- ¹³C₆ (sodium) is the ¹³C₆ labeled Oxacillin (sodium). Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.

HY-W654157

Dicloxacillin-13C4 sodium hydrate
Dicloxacillin- ¹³C₄ sodium hydrate is the ¹³C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to study infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus .

HY-A0269S

Mecillinam-d12
Mecillinam-d₁₂ is deuterium labeled Mecillinam. Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms .

HY-B0712S1

Ceftriaxone-13C2,d3 triethylammonium salt

Ceftriaxone-13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .

HY-B1252AS

Cefalonium-d4 hydrate
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

HY-B1459AS

Dicloxacillin-13C4
Dicloxacillin- ¹³C₄ is the ¹³C labeled Dicloxacillin (HY-B1459A) . Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus .

HY-A0294S

Ertapenem-d4

Ertapenem-d₄ (MK-0826-d₄) is deuterium labeled Ertapenem. Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .

HY-W746564

L-(+)-Ampicillin-d5
L-(+)-Ampicillin-d₅ (L-(+)-α-Aminobenzylpenicillin-d₅) is the deuterium labeled L-(+)-Ampicillin (HY-B0522C). L-(+)-Ampicillin (L-(2S) ampicillin) is the L-isomer of Ampicillin (HY-B0522). Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria .

HY-W752893

D-4-Hydroxyphenylglycine-d5-1
D-4-Hydroxyphenylglycine-d₅-1 (D-(-)-4-Hydroxyphenylglycine-d₅-1) is the deuterium labeled D-4-Hydroxyphenylglycine (HY-34588). D-4-Hydroxyphenylglycine (D-(-)-4-Hydroxyphenylglycine) is one of the most important raw materials used in the production of semisynthetic β-lactam antibiotics, such as Amoxicillin (HY-B0467A) and Cefadroxil (HY-B1190) .

Cat. No.	Product Name		Classification

HY-B2091

Azidocillin		Azide
Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam *antibiotic*. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases . Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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