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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
δ-Lactone
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "δ-Lactone" in MCE Product Catalog:
Cat. No.: HY-135755
CAS No.: 64053-02-7
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δ-Lactone, an A-ring degradation product, is also an important intermediate in the synthesis of Estrone (HY-B0234), Estradiol (HY-B0141), and their derivatives .
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1 Cited Publications
Synonyms: (±)-MevalonoLactone; MevaloLactone
Category:
Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields Inflammation/Immunology
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Synonyms: 5,6-EET; (±)5,6-EpETrE
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5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 (IC50=0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2.
Cat. No.: HY-W587796
CAS No.: 2641-81-8
Synonyms: 6-PGδL; 6-Phosphonoglucono-D-Lactone
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6-Phosphoglucono-δ-lactone (6-PGδL), a reversal substrate of glucose-6-phosphate dehydrogenase (G6PD), is an intermediate compound in the oxidative branch of the pentose phosphate pathway (PPP). 6-Phosphoglucono-δ-lactone produced from D-glucose-6-phosphate by glucose-6-phosphate dehydrogenase (G6PDH) and is converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone can be used for heart failure, type 2 diabetes and cancers research .
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Cat. No.: HY-125863C
CAS No.: 9001-40-5
Synonyms: G6PD, Bacillus sp.
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Glucose-6-phosphate dehydrogenase, Bacillus sp. (G6PD, Bacillus sp.) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase, Bacillus sp. is induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl in Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. is used in research related to diabetic complications .
Cat. No.: HY-P3990
CAS No.: 1029227-48-2
Synonyms: (±)-MevalonoLactone-d7; MevaloLactone-d7
Cat. No.: HY-125863B
CAS No.: 9001-40-5
Synonyms: G6PD (yeast, recombinant)
Research Areas:
Glucose 6-phosphate dehydrogenase (yeast, recombinant) (G6PD (yeast, recombinant)) is a recombinant enzyme requiring NADP + as a coenzyme. Glucose 6-phosphate dehydrogenase (yeast, recombinant) catalyzes the oxidative dehydrogenation of glucose-6-phosphate to form 6-phosphoglucono-δ-lactone, as well as the reduction of NADP + to NADPH. Glucose 6-phosphate dehydrogenase (yeast, recombinant) relies on the amino acid Arg-52 to bind NADP +. Glucose 6-phosphate dehydrogenase (yeast, recombinant) undergoes competitive inhibition by NADPH and strong inhibition by zinc ions (Zn 2+). Glucose 6-phosphate dehydrogenase (yeast, recombinant) is an enzyme in the pentose phosphate pathway, which is one of the glucose metabolic pathways. Glucose 6-phosphate dehydrogenase (yeast, recombinant) can be used for the quantitative detection of ATP, glucose and creatine kinase .
Cat. No.: HY-125863A
CAS No.: 9001-40-5
Synonyms: G6PD (Leuconostoc sp., recombinant)
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Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) (G6PD (Leuconostoc sp., recombinant)) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) can be induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of bacteria. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) is used in research related to diabetic complications .
Cat. No.: HY-146970
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Lankacyclinone C is a lankacidin C congener lacking the δ-lactone moiety, with antitumor activity .
Cat. No.: HY-P1720
CAS No.: 19246-24-3
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Cat. No.: HY-N10391
CAS No.: 1003600-48-3
Synonyms: Cleistenolide
Category:
Infection Ketones, Aldehydes, Acids Plants Annonaceae Disease Research Fields Cleistochlamys kirkii Oliver Cancer
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Cat. No.: HY-107855S1
CAS No.: 61219-76-9
Synonyms: (±)-MevalonoLactone-d3; MevaloLactone-d3
Cat. No.: HY-107855R
CAS No.: 674-26-0
Synonyms: (±)-MevalonoLactone (Standard); MevaloLactone (Standard)
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Cat. No.: HY-130229
CAS No.: 213126-92-2
Synonyms: (±)5,6-DiHETrE Lactone
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5,6-DiHET lactone ((±)5,6-DiHETrE lactone) is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS.1 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively. It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME.
Cat. No.: HY-P1709
CAS No.: 141912-59-6
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Cat. No.: HY-N9310
CAS No.: 19131-13-6
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Cat. No.: HY-107855S2
CAS No.: 53771-22-5
Synonyms: (±)-MevalonoLactone-13C; MevaloLactone-13C
Cat. No.: HY-107855S4
CAS No.: 287111-36-8
Synonyms: (±)-MevalonoLactone-13C2; MevaloLactone-13C2
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
