32 Results for "

DAN 2163-d5

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "DAN 2163-d5" in MCE Product Catalog:

37
37 Publications Verification
Cat. No.: HY-N0135
CAS No.: 568-72-9
Synonyms: DAN Shen ketone
Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.
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19
19 Cited Publications
Cat. No.: HY-B2163
CAS No.: 472-61-7
Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis, impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed .
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9
9 Cited Publications
Cat. No.: HY-N1913
CAS No.: 76822-21-4
Synonyms: DAN shen suan A; Salvianic acid A
Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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9
9 Cited Publications
Cat. No.: HY-N1913A
CAS No.: 81075-52-7
Synonyms: DAN shen suan A sodium; Salvianic acid A sodium
Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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2
2 Cited Publications
Cat. No.: HY-14545
CAS No.: 71675-85-9
Purity:  99.92%
Synonyms: (Rac)-Aramisulpride; (Rac)-Esamisulpride; DAN 2163
Research Areas:  

Neurological Disease

Amisulpride ((Rac)-Aramisulpride) is a racemic (50:50) mixture of the R-Amisulpride (HY-109167) and S-Amisulpride (HY-126068). Amisulpride is a dopamine D2/D3 receptor antagonist with Ki values of 2.8 and 3.2 nM for human dopamine b>D2 and b>D3, respectively. Amisulpride is a 5-HT7 receptor antagonist with a Ki of 44 nM. Amisulpride can be used in psychiatric research .
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2
2 Cited Publications
Cat. No.: HY-14545A
CAS No.: 81342-13-4
Purity:  99.79%
Synonyms: (Rac)-Aramisulpride hydrochloride; (Rac)-Esamisulpride hydrochloride; (Rac)-DAN 2163 hydrochloride
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.
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1
1 Cited Publications
Cat. No.: HY-P7822
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CER1; DAN Domain Family Member 4; Cerberus 1, DAN Family BMP Antagonist; Cerberus 1 (Xenopus Laevis) Homolog (Cysteine Knot Superfamily); DAND4; Cerberus 1, Cysteine Knot Superfamily, Homolog (Xenopus Laevis); Cerberus-Related Protein; Cerberus 1, Cystein
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-N2163
CAS No.: 172760-03-1
Mudanpioside C is a protein disulfide isomerase (PDI) inhibitor with a human IC50 of 3.31 μM and human Kd of 3.9 μM. Mudanpioside C suppresses collagen-induced platelet aggregation, interferes with platelet activation, adhesion, and spreading. Mudanpioside C can be used for the research of cardiovascular diseases .
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Cat. No.: HY-126068
CAS No.: 71675-92-8
Purity:  99.04%
Synonyms: (S)-Amisulpride; (S)-Aramisulpride; (S)-DAN 2163
Research Areas:  

Neurological Disease

Esamisulpride ((S)-Amisulpride) is the S-isomer of Amisulpride (HY-14545). Esamisulpride is a potent dopamine D2/D3 receptor antagonist with Ki values of 4.43 nM for D2R and 0.72 nM for D3R. Esamisulpride is a 5-HT7 receptor antagonist with a Ki of 900 nM. Esamisulpride can be used in the research of schizophrenia and depression .
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Cat. No.: HY-109167
CAS No.: 71675-90-6
Purity:  99.49%
Synonyms: (R)-Amisulpride; (R)-Esamisulpride; (R)-DAN 2163
Research Areas:  

Neurological Disease

Aramisulpride (R-(+)-Amisulpride) is the R-isomer of Amisulpride (HY-14545). Aramisulpride is a 5-HT7 receptor antagonist with a Ki value of 22 nM. Aramisulpride is a D2/D3 receptor antagonist with a Ki value of 140 nM for D2R and a Ki value of 13.9 nM for D3R. Aramisulpride can be used in psychiatric research .
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Cat. No.: HY-14545S
CAS No.: 1216626-17-3
Purity:  98.83%
Synonyms: (Rac)-Aramisulpride-d5; (Rac)-Esamisulpride-d5; DAN 2163-d5
Amisulpride-d5 is the deuterium labeled Amisulpride. Amisulpride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively .
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Cat. No.: HY-143498
CAS No.: 2411584-25-1
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

ERCC1-XPF-IN-1 is a potent and high-affinity ERCC1-XPF inhibitor with IC50 value of 0.49 μM. ERCC1-XPF-IN-1 has the capacity to potentiate the cytotoxicity effect of UV radiation and inhibiting DAN repair, by the inhibition of removal of CPDs, and cyclophosphamide toxicity to colorectal cancer cells .
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Cat. No.: HY-23206
CAS No.: 1049720-51-5
Research Areas:  

Others

DAN-1 EE hydrochloride is a fluorescent indicator, which can be used for the detection of nitrite content in vitro and biological process .
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Cat. No.: HY-N0135R
CAS No.: 568-72-9
Synonyms: DAN Shen ketone (Standard)
Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.
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Cat. No.: HY-122307
CAS No.: 54935-03-4
Synonyms: DAN-603
Target:  

Bacterial

Research Areas:  

Metabolic Disease

Sulisatin (DAN-603) is an anionic laxative that is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon during oral administration .
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Cat. No.: HY-122307A
CAS No.: 54935-04-5
Synonyms: DAN-603 disodium
Target:  

Bacterial

Research Areas:  

Metabolic Disease

Sulisatin (DAN-603) disodium is an anionic diarrhea-promoting compound. During oral administration, Sulisatin disodium is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon .
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Cat. No.: HY-109167A
CAS No.: 2129505-46-8
Synonyms: (R)-Amisulpride hydrochloride; (R)-Esamisulpride hydrochloride; (R)-DAN 2163 hydrochloride
Research Areas:  

Neurological Disease

Aramisulpride hydrochloride is a 5-HT7 receptor antagonist with a Ki value of 22 nM. Aramisulpride hydrochloride is a D2/D3 receptor antagonist with a Ki value of 140 nM for D2R and a Ki value of 13.9 nM for D3R. Aramisulpride hydrochloride can be used in psychiatric research .
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Cat. No.: HY-14545R
CAS No.: 71675-85-9
Synonyms: (Rac)-Aramisulpride (Standard); (Rac)-Esamisulpride (Standard); DAN 2163 (Standard)
Amisulpride (Standard) is the analytical standard of Amisulpride. This product is intended for research and analytical applications. Amisulpride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively.
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Cat. No.: HY-D2163
AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules .
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