12 Results for "

2-Fluoroadenosine

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "2-Fluoroadenosine" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W039442
CAS No.: 64183-27-3
Research Areas:  

Infection Cancer

2′-Deoxy-2′-fluoroadenosine is a fluorinated deoxyadenosine with antitumor and antiviral activity, able to interfere with viral or cancer cell replication by being incorporated into DNA. 2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP [2] .
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Cat. No.: HY-W011517
CAS No.: 146-78-1
Synonyms: 2FA
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions [2].
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Cat. No.: HY-W011517R
CAS No.: 146-78-1
Synonyms: 2FA (Standard)
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions [2].
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Cat. No.: HY-P5372A
Research Areas:  

Cancer

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
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Cat. No.: HY-P5373
CAS No.: 237409-87-9
Target:  

Peptides

Research Areas:  

Others

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)
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Cat. No.: HY-P5372
CAS No.: 211190-38-4
Research Areas:  

Cancer

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2, a bioactive peptide, is a selective Protease activating receptor 1 (PAR-1) agonist over PAR-2. PAR-1 belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type' .
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Cat. No.: HY-134033A
Synonyms: 2'-Fluoro dATP sodium
Research Areas:  

Infection

2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium (2'-fluoro dATP) is a fluorinated derivative of ATP (HY-B2176). 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium is a substrate and an inhibitor for E.coli DNA-dependent RNA polymerase, with a Ki of 200 µM .
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Cat. No.: HY-154396
Research Areas:  

Cancer

8-Chloro-2’-deoxy-2’-fluoroadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-154156
Research Areas:  

Cancer

2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-136649
Synonyms: AfTP tetralithium, 2′-Fluoro-2′-deoxy-ATP (tetralithium)
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium is an ATP analog, it exerted a strong but mixed-type inhibition on poly(AU) synthesis.
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Cat. No.: HY-134033
CAS No.: 73449-07-7
Synonyms: 2'-Fluoro dATP
Research Areas:  

Others

2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate (2'-Fluoro dATP) is a monomeric raw material that can be used for nucleic acid synthesis.
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Cat. No.: HY-175135
Research Areas:  

Others

Rp-2'-Deoxy-2'-fluoroadenosine-5'-O-(1-thiotriphosphate) (sodium) is an isomer of the sulfur-containing nucleoide derivative 2’-F-dATP-α-S.
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