2 Results for "

Aβ(17-42)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Aβ(17-42)" in MCE Product Catalog:

Cat. No.: HY-P3779
CAS No.: 155178-13-5
Synonyms: Aβ(17-42)
Target:  

Apoptosis

Research Areas:  

Neurological Disease

Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP). Amyloid 17-42 can induce neuronal apoptosis via a Fas-like/caspase-8 activation pathway .
loading...
    loading...
Cat. No.: HY-114508
CAS No.: 1083-30-3
Purity:  99.87%
Synonyms: 3-Phenylpropiophenone; β-Phenylpropiophenone
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Dihydrochalcone (3-Phenylpropiophenone) is a Aβ aggregation inhibitor. Dihydrochalcone destabilizes Aβ17-42 protofibrils by disrupting the β-sheet of β1 region. Dihydrochalcone destabilizes both U-shaped Aβ40/Aβ42 protofibrils and S-shaped Aβ42 protofibrils by binding to the protofibril cavity. Dihydrochalcone is the main component of daemonorops draco tree .
loading...
    loading...