1. Search Result
Search Result
Results for "

Aβ-IN-4

" in MedChemExpress (MCE) Product Catalog:

133

Inhibitors & Agonists

1

Fluorescent Dyes

15

Biochemical Assay Reagents

3

Peptides

1

MCE Kits

1

Inhibitory Antibodies

26

Natural
Products

8

Isotope-Labeled Compounds

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-E70289

    BovIN B4GALT1 (Y289L)

    Endogenous Metabolite Others
    Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Bovin B4GALT1 (Y289L)) is a mutated form of bovine-derived galactosyltransferase with a mutation at the Y289L genetic site. Bovin beta-1,4-galactosyltransferase 1 can label O-GlcNAcylated proteins with an N-azidoacetylgalactosamine (GalNAz) group. This labeling method allows for the specific, unbiased, and global labeling of O-GlcNAcylated proteins. After labeling, the appended azide group can react with a wide variety of alkyne-modified chemical probes, facilitating multiple downstream analyses .
    Bovin beta-1,4-galactosyltransferase 1 (Y289L)
  • HY-112108
    Chitosan oligosaccharide
    5 Publications Verification

    COS

    AMPK Endogenous Metabolite Metabolic Disease Cancer
    Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways.
    Chitosan oligosaccharide
  • HY-E70285

    B4GALT1 (Y285L)

    Endogenous Metabolite Metabolic Disease
    beta-1,4-Galactosyltransferase 1 (Y285L) can enzymatic synthesis of the LacdiNAc motif. beta-1,4-Galactosyltransferase 1 (Y285L) can transfer of GalNAc from UDP-GalNAc .
    beta-1,4-Galactosyltransferase 1 (Y285L)
  • HY-B1204S

    ErgamINe-α,α,β,β-d4 dihydrochloride

    Histamine Receptor Endogenous Metabolite Neurological Disease Endocrinology Cancer
    Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
    Histamine-α,α,β,β-d4 dihydrochloride
  • HY-E70068

    Others Others
    Endo-β-N-acetylglucosaminidase (Endo S) is a family 18 glycosyl hydrolase secreted by Streptococcus pyogenes. Endo-β-N-acetylglucosaminidase (Endo S) exclusively hydrolyzes the β-1,4-di-N-acetylchitobiose core of the asparagine-linked complex-type glycan on Asn-297 of the γ-chains of IgG antibody .
    Endo-β-N-acetylglucosaminidase (Endo S)
  • HY-W114954

    Drug Derivative Others
    Guaiacylglycerol-beta-guaiacyl ether is a phenolic β-O-4 type lignin model compound that mimics the most common β-O-4 aryl ether linkages in plant lignin. Guaiacylglycerol-beta-guaiacyl ether can be degraded by Bacillus amyloliquefaciens CotA. Guaiacylglycerol-beta-guaiacyl ether is a commonly used model compound for studying the β-O-4 inter-unit linkage, the most abundant substructure in lignin, and can be applied to investigate the reaction pathway of vanillin preparation via alkaline nitrobenzene oxidation .
    Guaiacylglycerol-beta-guaiacyl ether
  • HY-E70131
    Endo H, Streptomyces picatus
    1 Publications Verification

    Endo-β-N-acetylglucosamINidase H

    Others Metabolic Disease
    Endo H, Streptomyces picatus (Endo-β-N-acetylglucosaminidase H), isolated from Streptomyces plicatus, hydrolyzes the central glycosidic bond of the β1, 4-di-N-acetylchitobiose core in asparagine-linked oligosaccharides .
    Endo H, Streptomyces picatus
  • HY-P2869C

    Endogenous Metabolite Metabolic Disease
    β1-3,4 Galactosidase is a highly specific exoglycosidase that catalyzes the hydrolysis of terminal β1-3 and β1-4 linked galactose residues from oligosaccharides .
    β1-3,4 Galactosidase
  • HY-E70110

    Others Others
    Endo-1,4-β-mannanase is an important catalytic agent that randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose .
    Endo-1,4-β-mannanase
  • HY-130778

    Endogenous Metabolite Cardiovascular Disease Others
    N,N'-Diacetylchitobiose is a dimer of β(1,4) linked N-acetyl-D glucosamine. N,N'-Diacetylchitobiose is the hydrolysate of chitin and can be used as alternative carbon source by E. coli. N,N'-Diacetylchitobiose also reverses myocardial depression [4].
    N,N'-Diacetylchitobiose
  • HY-P3017

    CtXyn11A; EC 3.2.1.8

    Poly(ADP-ribose) Glycohydrolase (PARG) Others
    Endo-1,4-β-xylanase (Xylanase) is an arabinoxylan (AX) degrading enzyme and a glycoside hydrolase, is often used in biochemical studies. Endo-1,4-β-xylanase cleaves the β-xylosidic bond between two d-xylopyranosyl residues linked in β-(1,4) .
    Endo-1,4-β-xylanase
  • HY-P2869B

    Endogenous Metabolite Metabolic Disease
    β1-4 Galactosidase, E. coli is a highly specific exoglycosidase that catalyzes the hydrolysis of terminal, non-reducing β1-4 linked galactose residues from oligosaccharides .
    β1-4 Galactosidase, E. coli
  • HY-P3187

    DNA/RNA Synthesis Others
    Exo-1,4-β-xylosidase is an exonuclease that specifically acts on the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. Exo-1,4-β-xylosidase is Ca 2+-dependent and reversibly binds to metal ions to catalyze the hydrolysis of β-1,4 glycosidic bonds, thereby degrading xylan to produce xylose. Exo-1,4-β-xylosidase can be used in research fields such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes .
    exo-β-1,4-Xylosidase, Cellulosimicrobium cellulans sp. 21
  • HY-P2816

    Biochemical Assay Reagents Others
    Xylanase is an enzyme targeting 1,4-β-D-xylan that randomly cleaves the β-1,4 backbone of xylan, a complex polysaccharide in plant cell walls. Xylanase finds applications in the food, feed and industrial sectors, including pulp and paper processing, baking, animal feed improvement, and biotransformation of waste .
    Xylanase
  • HY-P2869E

    Endogenous Metabolite Metabolic Disease
    β1-3,4,6 Galactosidase is a broad specificity exoglycosidase that catalyzes the hydrolysis of terminal, non-reducing β1-3 β1-4 and β1-6 linked galactose residues from oligosaccharides, with β1-6 linked galactose residues at a slower rate .
    β1-3,4,6 Galactosidase
  • HY-E70046

    Endogenous Metabolite Metabolic Disease
    beta-1,4-Galactosyltransferase (LgtB) (EC 2.4.1.90) (B4GALT1 (LgtB)) is often used in biochemical studies. beta-1,4-Galactosyltransferase (LgtB) catalyzes the reaction involving UDP-galactose and N-acetylglucosamine for the production of galactose beta-1,4-N-acetylglucosamine .
    β-1,4-Galactosyltransferase, neisseria meningitides
  • HY-N1915

    Endogenous Metabolite Metabolic Disease
    Cellohexaose is a glucose polymer with two or more glucose monomers produced from the breakdown of cellulose, consisting of a condensation of beta (1-4) linked D-glucose monomers .
    Cellohexaose
  • HY-W587733

    17,20β-P; 17,20β-DHP

    Endogenous Metabolite Endocrinology
    17α,20β-Dihydroxy-4-pregnen-3-one (17,20β-P) is a maturation-inducing steroid .
    17α,20β-Dihydroxy-4-pregnen-3-one
  • HY-E70138

    EC:2.4.1.133; B4GALT7

    Glycosyltransferase Others
    β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .
    β-1,4-Galactosyltransferase 7
  • HY-P990011

    ACU-193

    Amyloid-β Neurological Disease
    Sabirnetug is a humanized IgG2κ antibody targeting the Amyloid-β A4 precursor protein.
    Sabirnetug
  • HY-W028127

    IKK Inflammation/Immunology
    IKKβ-IN-4 (compound 14) is an IkappaB kinase-β ( IKKβ ) inhibitor with IC50 value of 1.9 μM. IKKβ is a key enzyme in the NF-κB signaling pathway and is involved in the development of many diseases .
    IKKβ-IN-4
  • HY-146140

    Amyloid-β Neurological Disease
    Aβ-IN-4 (compound 12) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-4 inhibits Aβ42 aggregation. However, Aβ-IN-4 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-4 can not change the aggregation state of Aβ42 into a nontoxic one .
    Aβ-IN-4
  • HY-E70060

    EB4GALT1 (LgtE)

    Others Others
    beta-1,4-Galactosyltransferase (LgtE) (EB4GALT1 (LgtE)) catalyzes the reaction involving UDP-galactose and N-acetylglucosamine for the production of galactose beta-1,4-N-acetylglucosamine .
    beta-1,4-Galactosyltransferase (LgtE)
  • HY-E70013A

    EC 3.2.1.73

    Glycosidase Others
    Licheninase (EC 3.2.1.73) is a glycoside hydrolase is active on the β-glucan cell wall of cereals, fungi, and seaweed. Licheninase specifically hydrolyzes β(1→4) linkages in mixed linkage β(1→3)/β(1→4)-glucans. Licheninase improves cellulose degradation .
    Licheninase
  • HY-E70136

    Keratan-sulfate endo-1,4-beta-galactosidase; Keratanase

    Others Metabolic Disease
    Endo-β-Galactosidase catalyzes the hydrolysis of internal β1-4 galactose linkages in unbranched, repeating poly-N-acetyllactosamine ([GlcNAc- (1-3)Gal- (1-4)]n) structures .
    Endo-β-Galactosidase
  • HY-P2859

    Endogenous Metabolite Metabolic Disease
    Chitosanase is a glycosyl hydrolase that catalyzes the endo hydrolysis of β-1,4-glycosidic bonds of partially acetylated chitosan to release chitosan oligosaccharides (COS). Chitosanases can convert high molecular weight chitosan into functional chitooligosaccharides with low molecular weight .
    Chitosanase
  • HY-E70879

    EndoM N175Q

    Glycosidase Others
    Endoglycosidase M (N175Q mutant) (EndoM N175Q) can transfer natural N-glycans or oxazoline N-glycans to any peptide or protein with a GlcNAc residue to form a β1-4-glycosidic linkage. Endoglycosidase M (N175Q mutant) is a useful tool in the synthesis of homogeneous glycopeptides and glycoproteins .
    Endoglycosidase M (N175Q mutant)
  • HY-164032

    7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate

    GnRH Receptor Endocrinology
    Dimethandrolone undecanoate (7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate) exhibits withrogens and progesterone activity. Dimethandrolone undecanoate inhibits production of gonadotropins, suppresses testosterone production, and thus inhibits sperm production. Dimethandrolone undecanoate is potent for development of male hormone contraceptives .
    Dimethandrolone undecanoate
  • HY-P2769A

    Biochemical Assay Reagents Others
    Thermostable β-Agarase is a hydrolase that can hydrolyze the β-1,4 linkages in agarose to produce neoagaro-oligosaccharides, and it can be used to extract DNA and RNA from gels. Compared to conventional β-Agarase, Thermostable β-Agarase exhibits higher heat resistance and stronger hydrolytic activity. The thermostable properties of Thermostable β-Agarase simplify experimental procedures and make it suitable for the rapid purification of intact large DNA molecules .
    Thermostable β-Agarase
  • HY-B2220B

    Endogenous Metabolite Others
    Thermostable cellulase recombinant is a cellulose hydrolase present in hyperthermophiles, which catalyzes the hydrolysis of β-1,4 glycosidic bonds in cellulose. Thermostable cellulase recombinant targets carboxymethyl cellulose (CMC) as its primary substrate, and retains high residual activity even after incubation at high temperatures. The activity of Thermostable cellulase recombinant is inhibited by ionic and non-ionic detergents, and can be enhanced by cobalt ions. Thermostable cellulase recombinant can be applied in the paper industry .
    Thermostable cellulase (recombinant)
  • HY-P3187B

    DNA/RNA Synthesis Others
    exo-β-1,4-xylosidase, Bacteroides ovatus (EC.3.2.1.37) is an exonuclease that specifically acts on the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. exo-β-1,4-xylosidase is Ca 2+-dependent and reversibly binds to metal ions to catalyze the hydrolysis of β-1,4 glycosidic bonds, thereby degrading xylan to produce xylose. exo-β-1,4-xylosidase can be used in research fields such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes .
    exo-β-1,4-xylosidase, Bacteroides ovatus
  • HY-P3187A

    DNA/RNA Synthesis Others
    exo-β-1,4-xylosidase,Clostridium stercorarium (EC.3.2.1.37) is an exonuclease that specifically acts on the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. exo-β-1,4-xylosidase is Ca 2+-dependent and reversibly binds to metal ions to catalyze the hydrolysis of β-1,4 glycosidic bonds, thereby degrading xylan to produce xylose. exo-β-1,4-xylosidase can be used in research fields such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes .
    exo-β-1,4-xylosidase, Clostridium stercorarium
  • HY-E70046A

    BovINe B4GALT1

    Glycosyltransferase Others
    Bovine beta-1,4-Galactosyltransferase (Bovine B4GALT1) is a one member of the glycosyltransferase family of enzymes. Bovine beta-1,4-Galactosyltransferase transfers galactose from UDP-galactose to N-acetylglucosamine (GlcNAc) to produce N-acetyllactosamine with a β-1,4-glycosidic linkage .
    Bovine beta-1,4-Galactosyltransferase
  • HY-179112

    PROTACs IKK Nuclear Hormone Receptor 4A/NR4A Caspase Necroptosis Apoptosis Inflammation/Immunology Cancer
    PROTAC IKKβ/NR4A1 degrader-1 is a highly efficient and effective dual-PROTAC degrader targeting IKKβ and NR4A1. PROTAC IKKβ/NR4A1 degrader-1 can increase the levels of caspase 3 and cleaved caspase 3 proteins, while the necroptosis marker RIP kinase remained unchanged, indicating that it can induce apoptosis. PROTAC IKKβ/NR4A1 degrader-1 can be used for the study of Acute myeloid leukemia (AML). Red: IKKβ/NR4A1 ligand (HY-13067); Blue: E3 ligase CRBN ligand (HY-14658); Black: Linker (HY-79577) .
    PROTAC IKKβ/NR4A1 degrader-1
  • HY-W145558

    Gal beta(1-4)Glc-beta-MP

    Biochemical Assay Reagents Others
    Galβ(1-4)Glc-β-MP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Galβ(1-4)Glc-β-MP
  • HY-N10885

    Others Others
    α,β-Dihydro-4,6-dihydroxy-2-methoxy-3-methylchalcone (compound 7) is a nature product that could be isolated from dragons blood of Daemonorops draco .
    α,β-Dihydro-4,6-dihydroxy-2-methoxy-3-methylchalcone
  • HY-157441

    Cholinesterase (ChE) Amyloid-β Neurological Disease
    AChE/Aβ-IN-4 is a dual inhibitor of acetylcholinesterase (AChE) and β-amyloid (Aβ) aggregation, with the IC50 values of 1.72 ± 0.18 μM and 1.42 ± 0.3 μM, respectively. AChE/Aβ-IN-4 plays an impotant role in neurological disorders, such as Alzheimer’s disease .
    AChE/Aβ-IN-4
  • HY-177854

    Amyloid-β Neurological Disease
    Aβ aggregation-IN-4 can alleviate the neurotoxicity of amyloid-β protein (Aβ) and significantly reduce the level of oligomeric complexes of Aβ (Aβ-OCs). Aβ aggregation-IN-4 does not decrease the level of amyloid-β protein (Aβ). Aβ aggregation-IN-4 attenuates Aβ oligomerization and prevents oligomer-induced death of primary cortical neurons. Aβ aggregation-IN-4 can be used for the study of Alzheimer’s disease (AD) .
    Aβ aggregation-IN-4
  • HY-E70191

    EC:2.4.1.22; B4GALT2

    Glycosyltransferase Others
    β-1,4-Galactosyltransferase 2 catal exclusive specificity for the donor substrate UDP-galactose and all transfer galactosein a beta1,4 linkage .
    β-1,4-Galactosyltransferase 2
  • HY-P4892

    Amyloid-β Others
    Amyloid β-Protein (4-42) is aAβ Fragment.
    Amyloid β-Protein (4-42)
  • HY-P1787

    Amyloid-β Neurological Disease
    β-Amyloid (4-10) is an epitope for the polyclonal anti-Aβ(1-42) antibody, reduces amyloid deposition in a transgenic Alzheimer disease mouse model .
    β-Amyloid (4-10)
  • HY-P2858

    Glycosidase Metabolic Disease
    β-Mannosidase is a lysosomal exo‑acting enzyme. β-Mannosidase catalyzes hydrolysis of β‑1,4‑linked mannosides, non‑reducing terminal mannoses in N‑glycoproteins, and Man‑β‑1,4‑GlcNAc linkages to release mannose. β-Mannosidase contributes to glycoprotein catabolism and supports Bifidobacteria colonization via N‑glycan depolymerization. β-Mannosidase can be used for the research of β-mannosidosis and β-mannosidase deficiency [4].
    β-Mannosidase
  • HY-112108D

    COS (MW 2000)

    Biochemical Assay Reagents Others
    Chitosan oligosaccharide (MW 2000) (COS (MW 2000)) is a degradation product of chitosan. It is an oligosaccharide composed of 2-20 glucosamine groups linked by β-(1→4) glycosidic bonds .
    Chitosan oligosaccharide (MW 2000)
  • HY-E70602

    Bacterial Others
    T4 lysozyme is derived from a recombinant E.coli strain and can lyse bacterial cell walls. T4 lysozyme acts on the peptidoglycan of bacterial cell walls and hydrolyzes the β-1,4 bond between N-acetylmuramic acid and N-acetylglucosamine .
    T4 lysozyme
  • HY-E70179

    EC 2.4.1.149; B4GAT1; β3GNTI

    Glucosylceramide Synthase (GCS) Others
    beta-1,4-Glucuronyltransferase 1 is a glucosyltransferase. beta-1,4-Glucuronyltransferase 1 transfers glucuronic acid towards both α and β anomers of xylose .
    β-1,4-Glucuronyltransferase 1
  • HY-N9166

    Others Others
    erythro-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether (Compound 122) inhibits lettuce germination. erythro-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether can be isolated from Brassica fruticulosa .
    erythro-Guaiacylglycerol-β-O-4'-dehydrodisinapyl ether
  • HY-170663

    Glycosyltransferase Infection
    β-1,4-GALT1-IN-1 (Compound 6) is a β-1,4-GALT1 inhibitor, with an IC50 value of 6.2 μM. β-1,4-GALT1-IN-1 can be used in many pathology investigations such as cancer, autoimmune diseases and viral infections .
    β-1,4-GALT1-IN-1
  • HY-N15690

    Biochemical Assay Reagents Others
    3-(R)-3-β-Glucopyranosyloxy-4-hydroxybutanoic acid is a butanoic acid glucose. 3-(R)-3-β-Glucopyranosyloxy-4-hydroxybutanoic acid can be isolated from the methanol extract of dried whole plants of Anoectochilus formosanus Hay. 3-(R)-3-β-Glucopyranosyloxy-4-hydroxybutanoic acid can be formed in 3 types of regenerated plantlets in vitro .
    3-(R)-3-β-Glucopyranosyloxy-4-hydroxybutanoic acid
  • HY-172255

    PI4K Apoptosis Autophagy PI3K Akt Cancer
    PI4KIII beta inhibitor 4 (Compound 16) is a selective PI4KIIIβ inhibitor with an IC50 of 0.005 μM. PI4KIIIβ inhibitor 4 induces tumor cell apoptosis, cell cycle arrest, and autophagy by inhibiting the PI3K/AKT pathway. PI4KIIIβ inhibitor 4 can be used in the study of cancer .
    PI4KIII beta inhibitor 4
  • HY-N1870

    Bacterial Others
    1β-Hydroxy-4(15),5E,10(14)-germacratriene (compound 17) is a sesquiterpenoids that can be isolated from Chrysanthemum indicum.1β-Hydroxy-4(15),5E,10(14)-germacratriene significantly reduces PEDV nucleocapsid and spike protein synthesis.1β-Hydroxy-4(15),5E,10(14)-germacratriene shows various biological properties, such as antibacterial, antioxidant, and anti-inflammatory .
    1β-Hydroxy-4(15),5E,10(14)-germacratriene

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: