138 Results for "

Aβ-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (138)

138 Results for "Aβ-IN-4" in MCE Product Catalog:

Cat. No.: HY-146140
CAS No.: 2477606-97-4
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Aβ-IN-4 (compound 12) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-4 inhibits Aβ42 aggregation. However, Aβ-IN-4 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-4 can not change the aggregation state of Aβ42 into a nontoxic one .
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29
29 Publications Verification
Cat. No.: HY-B0498
CAS No.: 130641-38-2
Synonyms: AF2838
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity .
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7
7 Cited Publications
Cat. No.: HY-N1346
CAS No.: 301-19-9
Robinin is a flavonoid that can be extracted from the leaves of purple cowpea, inhibiting TGF-β, TLR4/NF-κB and TLR2-PI3k-AKT signaling pathways. Robinin exerts anti-inflammatory and anti-tumor effects. The combination of Robinin and Methotrexate (HY-14519) reduces inflammation in experimental arthritis, Robinin can decrease the Doxorubicin (HY-15142A) induced cardiac toxicity effect [4].
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5
5 Cited Publications
Cat. No.: HY-112108
CAS No.: 148411-57-8
Purity:  ≥91.0%
Synonyms: COS
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways.
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2
2 Cited Publications
Cat. No.: HY-E70131
CAS No.: 37278-88-9
Synonyms: Endo-β-N-acetylglucosamINidase H
Target:  

Endonuclease

Research Areas:  

Metabolic Disease

Endo H, Streptomyces picatus (Endo-β-N-acetylglucosaminidase H), isolated from Streptomyces plicatus, hydrolyzes the central glycosidic bond of the β1, 4-di-N-acetylchitobiose core in asparagine-linked oligosaccharides .
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2
2 Cited Publications
Cat. No.: HY-154629
CAS No.: 8008-74-0
Purity:  ≥98.0%
Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-κB, aspartate aminotransferase, alanine aminotransferase, IL-1β, IL-4 and nitric oxide. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin (HY-17394) and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities [4] .
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1
1 Cited Publications
Cat. No.: HY-B1204S
CAS No.: 344299-48-5
Synonyms: ErgamINe-α,α,β,β-d4 dihydrochloride
Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
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1
1 Cited Publications
Cat. No.: HY-E70046
CAS No.: 9054-94-8
Target:  

Glycosyltransferase

Research Areas:  

Metabolic Disease

beta-1,4-Galactosyltransferase (LgtB) (EC 2.4.1.90) (B4GALT1 (LgtB)) is often used in biochemical studies. beta-1,4-Galactosyltransferase (LgtB) catalyzes the reaction involving UDP-galactose and N-acetylglucosamine for the production of galactose beta-1,4-N-acetylglucosamine .
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1
1 Cited Publications
Cat. No.: HY-114464
CAS No.: 382-44-5
Purity:  98.09%
Synonyms: 4-Androsten-11β-ol-3,17-dione
11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor. As 4-androstenedione increases, measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism .
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1
1 Cited Publications
Cat. No.: HY-15927
CAS No.: 2492-87-7
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .
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1
1 Cited Publications
Cat. No.: HY-W013579
CAS No.: 2244-16-8
Synonyms: D-​Carvone
(S)-(+)-Carvone is an orally active natural product. (S)-(+)-Carvone increases the activity of antioxidant enzymes (SOD, CAT) and ROS, reduces the levels of oxidative stress markers (MDA, AChE), reduces the secretion of proinflammatory cytokines (IL-1β, IL-4, IL-6, IL-10), and downregulates NLRP3. (S)-(+)-Carvone increases the activities of caspase-8, -9 and -3. (S)-(+)-Carvone induces apoptotic death. (S)-(+)-Carvone has antimanic-like effect, liver protection and anticancer activity against skin cancer. (S)-(+)-Carvone improves memory and arthritis [4] .
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Cat. No.: HY-E70289
Synonyms: BovIN B4GALT1 (Y289L)
Target:  

Glycosyltransferase

Research Areas:  

Cancer

Bovin beta-1,4-galactosyltransferase 1 (Y289L) (Bovin B4GALT1 (Y289L)) is a mutated form of bovine-derived galactosyltransferase with a mutation at the Y289L genetic site. Bovin beta-1,4-galactosyltransferase 1 can label O-GlcNAcylated proteins with an N-azidoacetylgalactosamine (GalNAz) group. This labeling method allows for the specific, unbiased, and global labeling of O-GlcNAcylated proteins. After labeling, the appended azide group can react with a wide variety of alkyne-modified chemical probes, facilitating multiple downstream analyses .
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Cat. No.: HY-E70285
Synonyms: B4GALT1 (Y285L)
Target:  

Glycosyltransferase

Research Areas:  

Metabolic Disease

beta-1,4-Galactosyltransferase 1 (Y285L) can enzymatic synthesis of the LacdiNAc motif. beta-1,4-Galactosyltransferase 1 (Y285L) can transfer of GalNAc from UDP-GalNAc .
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Cat. No.: HY-E70068
CAS No.: 37278-88-9
Target:  

Others

Research Areas:  

Others

Endo-β-N-acetylglucosaminidase (Endo S) is a family 18 glycosyl hydrolase secreted by Streptococcus pyogenes. Endo-β-N-acetylglucosaminidase (Endo S) exclusively hydrolyzes the β-1,4-di-N-acetylchitobiose core of the asparagine-linked complex-type glycan on Asn-297 of the γ-chains of IgG antibody .
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Cat. No.: HY-W114954
CAS No.: 7382-59-4
Target:  

Drug Derivative

Research Areas:  

Others

Guaiacylglycerol-beta-guaiacyl ether is a phenolic β-O-4 type lignin model compound that mimics the most common β-O-4 aryl ether linkages in plant lignin. Guaiacylglycerol-beta-guaiacyl ether can be degraded by Bacillus amyloliquefaciens CotA. Guaiacylglycerol-beta-guaiacyl ether is a commonly used model compound for studying the β-O-4 inter-unit linkage, the most abundant substructure in lignin, and can be applied to investigate the reaction pathway of vanillin preparation via alkaline nitrobenzene oxidation .
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Cat. No.: HY-P2869C
CAS No.: 9031-11-2
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

β1-3,4 Galactosidase is a highly specific exoglycosidase that catalyzes the hydrolysis of terminal β1-3 and β1-4 linked galactose residues from oligosaccharides .
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Cat. No.: HY-130778
CAS No.: 35061-50-8
Purity:  99.95%
N,N'-Diacetylchitobiose is a dimer of β(1,4) linked N-acetyl-D glucosamine. N,N'-Diacetylchitobiose is the hydrolysate of chitin and can be used as alternative carbon source by E. coli. N,N'-Diacetylchitobiose also reverses myocardial depression [4].
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Cat. No.: HY-E70110
CAS No.: 37288-54-3
Research Areas:  

Others

Endo-1,4-β-mannanase is an important catalyst that randomly cleaves the β-1,4-linkages in the main chain of mannan, releasing short-chain β-1,4-mannan and mannose. The catalytic activity of Endo-1,4-β-mannanase toward locust bean gum is enhanced by Mn 2+, Co 2+, Ca 2+, Ba 2+, Triton X-100, sodium azide and N-ethylmaleimide, completely inhibited by Hg 2+ and N-bromosuccinimide, and partially inhibited by EDTA and Cu 2+. Endo-1,4-β-mannanase can be used in studies related to plant hemicellulose degradation, biomass saccharification, elimination of anti-nutritional factors in feed, and manno-oligosaccharide prebiotics .
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Cat. No.: HY-P3017
CAS No.: 9025-57-4
Synonyms: CtXyn11A; EC 3.2.1.8
Research Areas:  

Others

Endo-1,4-β-xylanase (Xylanase) is an arabinoxylan (AX) degrading enzyme and a glycoside hydrolase, is often used in biochemical studies. Endo-1,4-β-xylanase cleaves the β-xylosidic bond between two d-xylopyranosyl residues linked in β-(1,4) .
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Cat. No.: HY-P2869B
CAS No.: 9031-11-2
Target:  

Glycosidase

Research Areas:  

Infection Metabolic Disease

β1-4 Galactosidase, E. coli is a highly specific exoglycosidase that catalyzes the hydrolysis of terminal, non-reducing β1-4 linked galactose residues from oligosaccharides .
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