43 Results for "

A20

" in MedChemExpress (MCE) Product Catalog:
Products (43)

43 Results for "A20" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-15978
CAS No.: 1235481-90-9
Target:  

Others

Research Areas:  

Neurological Disease

P7C3-A20 is a derivative of P7C3 with potent proneurogenic and neuroprotective activity. P7C3-A20 exerts an antidepressant-like effect. P7C3-A20 can cross the blood-brain barrier and therefore has the potential for brain injury treatment .
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2
2 Cited Publications
Cat. No.: HY-156773
CAS No.: 2499664-52-5
Purity:  98.71%
Target:  

Apoptosis METTL3

Research Areas:  

Cancer

STM3006 is a highly potent, selective, and orally active inhibitor of METTL3 (IC50: 5 nM). STM3006 can reduce the m6A level, promote the formation of dsRNA, trigger a cell-intrinsic interferon response, and enhance the killing effect of T cells on tumors. STM3006 has anti-tumor activity, and its combination with anti-PD-1 immunotherapy yields better results .
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Cat. No.: HY-19763
CAS No.: 1235449-52-1
Synonyms: BEBT-908
Ifupinostat (BEBT-908) is a blood-brain barrier-permeable PI3K/HDAC inhibitor. Ifupinostat exerts anticancer activity against hematologic malignancies, lung cancer, colon cancer, brain cancer and other cancers. Ifupinostat inhibits the PI3K/AKT/mTOR signaling pathway, suppresses c-Myc expression and induces ferroptosis. Ifupinostat can be used in tumor research .
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Cat. No.: HY-P4193
CAS No.: 181272-91-3
Target:  

MHC

Research Areas:  

Inflammation/Immunology Cancer

AH1 is an immunodominant MHC class I-restricted nonamer peptide recognized by CD8 + cytotoxic T lymphocytes. AH1 derives from the envelope protein (gp70) of an endogenous ecotropic murine leukemia virus and is presented by the MHC class I L d molecule. AH1 can be used for the research of colorectal carcinoma .
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Cat. No.: HY-P99922
CAS No.: 2173096-82-5

Target:  

LAG-3

Research Areas:  

Cancer

Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft) .
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Cat. No.: HY-P1654
CAS No.: 932699-03-1
Target:  

Integrin

Research Areas:  

Cancer

A20FMDV2 is a highly selective αvβ6 integrin inhibitor with human IC50 values of 3 nM and binds with at least 1000-fold selectivity over other RGD-binding integrins. A20FMDV2 binds to the integrin’s RGD-binding site, induces rapid integrin internalization, and delays post-internalization integrin recycling to the cell surface. A20FMDV2 can be used for the research of pancreatic cancer, breast cancer, colorectal cancer, ovarian cancer, oral squamous cell carcinoma .
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Cat. No.: HY-P99983

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Mouse IgG1 (D265A) kappa, Isotype Control is a mouse IgG1(D265A)κ isotype control with a D265A mutation and inactivity against mouse Fc gamma receptors (FcγR1, FcγR2, FcγR3, FcγR4) .
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Cat. No.: HY-178013
Target:  

ROCK

Research Areas:  

Inflammation/Immunology

ROCK2-IN-11 (Compound A20) is a selective ROCK2 inhibitor with an IC50 of 0.18 μM for ROCK2 over ROCK1. ROCK2-IN-11 can be used for idiopathic pulmonary fibrosis and cGVHD research .
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Cat. No.: HY-P990180
Anti-Mouse NKG2A/C/E Antibody (20D5) is an anti-mouse NKG2A/C/E IgG2a monoclonal antibody. Anti-Mouse NKG2A/C/E Antibody (20D5) can activate natural killer (NK) and CD8 + T cells. Anti-Mouse NKG2A/C/E Antibody (20D5) can exacerbate liver pathological damage by enhancing the activation of iNKT cells. Anti-Mouse NKG2A/C/E Antibody (20D5) can be used for researches on cancer and immunology such as lymphoma .
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Cat. No.: HY-15977
CAS No.: 1235481-43-2
Target:  

Drug Isomer

Research Areas:  

Neurological Disease

(S)-P7C3-OMe, P7C3-A20 hydroxylated analog, is the (S)-enantiomer of P7C3-OMe. P7C3-OMe is a pro-neurogenic compound, can be used for the research of neuropsychiatric and/or neurodegenerative disease .
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Cat. No.: HY-173490
Target:  

Fungal

Research Areas:  

Infection

Antifungal agent 131 (compound A20) is an antifungal compound with a minimum inhibitory concentration (MIC) of 64 μg/mL. Antifungal agent 131 demonstrates excellent antifungal potential when used in combination with Fluconazole (HY-B0101) .
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Cat. No.: HY-151506
CAS No.: 2274812-94-9
Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity .
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Cat. No.: HY-162329
Research Areas:  

Infection Inflammation/Immunology

Antibacterial agent 195 (compound A20), a Matrine (HY-N0164) derivative, is a potent antibiotic. Antibacterial agent 195 shows antibacterial activity against Gram-positive bacterium (MICS.aureus=0.021 mg/mL; MICP.acnes=0.030 mg/mL), Gram-negative bacterium (MICE.coli=0.092 mg/mL; MICC.albicans=0.379 mg/mL) and Fungus (MIC=2.806 mg/mL) .
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Cat. No.: HY-RS14789
Research Areas:  

Others

TNFAIP3 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFAIP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-CE00798
Synonyms: 20-Methylpentacosanoyl-coenzyme A
Research Areas:  

Metabolic Disease

20-Methylpentacosanoyl-CoA (20-Methylpentacosanoyl-coenzyme A) is a coenzyme A derivative.
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Cat. No.: HY-CE00801
Synonyms: 20-Methyltetracosanoyl-coenzyme A
Research Areas:  

Metabolic Disease

20-Methyltetracosanoyl-CoA (20-Methyltetracosanoyl-coenzyme A) is a coenzyme A derivative.
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Cat. No.: HY-CE00803
Synonyms: 20-Methyltricosanoyl-coenzyme A
Research Areas:  

Metabolic Disease

20-Methyltricosanoyl-CoA (20-Methyltricosanoyl-coenzyme A) is a coenzyme A derivative.
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Cat. No.: HY-P82486
Synonyms: TNFAIP3; OTUD7C; Tumor necrosis factor alpha-induced protein 3; TNF alpha-induced protein 3; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-RS13101
Research Areas:  

Others

SLC25A20 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC25A20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13307
Research Areas:  

Others

SLC6A20 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC6A20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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