3 Results for "

ABHD16A

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "ABHD16A" in MCE Product Catalog:

Cat. No.: HY-RS00090
Research Areas:  

Others

ABHD16A Human Pre-designed siRNA Set A contains three designed siRNAs for ABHD16A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-120299
CAS No.: 1646795-59-6
Purity:  ≥99.0%
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

KC01 is an effective inhibitor of ABHD16A, with IC50s of 90 nM for hABHD16A and 520 nM for mABHD16A. KC01 significantly reduces lyso-PSs, and decreases lyso-PS and LPS-induced cytokine production in mouse macrophages .
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Cat. No.: HY-121892
CAS No.: 1646795-60-9
(Z)-KC02 is an inhibitor of ABHD16A, the phosphatidylserine (PS) lipase that produces lyso-PS. Lysophosphatidylserine (lyso-PS) is a signaling lipid that regulates immune and neurological processes. It is associated with several neurological disorders such as retinitis pigmentosa and cataracts (PHARC). (Z)-KC02 depletes lyso-PS in lymphoblasts from PHARC subjects. (Z)-KC02 also reduces lyso-PS and lipopolysaccharide-induced cytokine production in macrophages and modulates lyso-PS metabolism in vivo .
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