9 Results for "

ALC0315

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "ALC0315" in MCE Product Catalog:

44
44 Cited Publications
Cat. No.: HY-138170
CAS No.: 2036272-55-4
Purity:  99.81%
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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Cat. No.: HY-142977
CAS No.: 1849616-54-1
Purity:  92.80%
6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) can be used in research on drug delivery, such as mRNA delivery .
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Cat. No.: HY-138170GL
CAS No.: 2036272-55-4
ALC-0315 (GMP Like) is ALC-0315 (HY-138170) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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Cat. No.: HY-173292
CAS No.: 2036273-14-8
Research Areas:  

Others

ALC-0315 analogue-4 is an ALC-0315 analog used in drug delivery.
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Cat. No.: HY-175049
CAS No.: 3117157-42-0
Target:  

Endogenous Metabolite

Research Areas:  

Others

ALC-0315 N-oxide is an impurity of ALC-0315 ( HY-138170). ALC-0315 is an ionisable aminolipid for mRNA delivery .
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Cat. No.: HY-172329
CAS No.: 3112713-48-8
Target:  

Liposome

Research Areas:  

Others

Q1-ALC-0315 iodide is a cationic quaternary ammonium lipid derivative of the ionizable cationic lipid ALC-0315 (HY-138170). Q1-ALC-0315-based LNPs can be used for lung-targeted mRNA delivery, which demonstrates high-performing firefly luciferase protein expression in the lungs .
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Cat. No.: HY-W800777
CAS No.: 2795212-31-4
Target:  

Liposome

Research Areas:  

Cancer

6-(3-Hydroxypropylamino)hexyl 2-hexyldecanoate is an ionizable lipid which can be used to make ALC-0315. The lipid has an ester bond adjacent to C6 relative to the amine nitrogen. The introduction of ester linkages can improve the clearance of the lipid in the liver.
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Cat. No.: HY-172332
CAS No.: 3097638-09-7
Target:  

Liposome NF-κB

Research Areas:  

Inflammation/Immunology Cancer

H1L1A1B3 is an ionizable cationic lipid used in the formation of lipid nanoparticles (LNPs) for the delivery of circular RNA (circRNA). H1L1A1B3-LNPs demonstrates a fourfold increase in circRNA transfection efficiency in lung cancer cells over ALC-0315 (HY-138170). H1L1A1B3 can activate the NF-κB/IRF immune pathways .
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Cat. No.: HY-W1130405
CAS No.: 2036273-20-6
Target:  

Liposome

Research Areas:  

Metabolic Disease

((1-Hydroxybutan-2-yl)azanediyl)bis(hexane-6,1-diyl) bis(2-hexyldecanoate) is an ionizable cationic lipid (pKa = 4.67) and a derivative of ALC-0315).
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