14 Results for "

ALCL

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "ALCL" in MCE Product Catalog:

14
14 Cited Publications
Referencia número: HY-10192
No. CAS: 761439-42-3
Pureza:  99.70%
Synonyms: TAE 684
Áreas de investigación:  

Cancer

NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM .
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Referencia número: HY-W016042
No. CAS: 13504-85-3
N-Cbz-Hydroxy-L-proline is a chiral N-Cbz-protected amino acid derivative. N-Cbz-Hydroxy-L-proline is commonly used in the synthesis of polypeptides and pharmaceutical intermediates. N-Cbz-Hydroxy-L-proline undergoes decarboxylation under AlCl3/HFIP conditions .
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Referencia número: HY-P99669
No. CAS: 640735-09-7
Synonyms: MDX-060

Target:  

TNF Receptor

Áreas de investigación:  

Cancer

Iratumumab (MDX-060) a human anti-CD30 IgG1κ monoclonal antibody. Iratumumab inhibits the growth of CD30-expressing tumor cells. Iratumumab can be used for research of Hodgkin's lymphoma (HL) and anaplastic large-cell lymphoma (ALCL) .
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Referencia número: HY-18030A
No. CAS: 2070009-30-0
Áreas de investigación:  

Cancer

CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK inhibitor with an IC50 value of 1.9 nM. CEP-28122 mesylate salt has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity. CEP-28122 mesylate salt can be used for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells .
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Referencia número: HY-18030
No. CAS: 1022958-60-6
Áreas de investigación:  

Cancer

CEP-28122, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK inhibitor with an IC50 value of 1.9 nM. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 has good pharmacodynamic and pharmacokinetic activity. CEP-28122 can be used for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells .
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Referencia número: HY-18315
No. CAS: 1251752-12-1
Target:  

JAK Apoptosis

Áreas de investigación:  

Cancer

Bayer-18 is an inhibitor for TYK2. Bayer-18 inhibits the viability of ALCL cell K299, SR786, Mac1 and Mac2a with IC50 of 2-3 µM, and induces apoptosis in K299 and SR786 .
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Referencia número: HY-P991638

Target:  

TNF Receptor

Áreas de investigación:  

Cancer

XmAb-2513 is a humanized monoclonal antibody inhibitor targeting CD30. XmAb-2513 has significant anti-proliferative activity and superior antibody-dependent cell-mediated cytotoxicity (ADCC) as well as antibody-dependent cell-mediated phagocytosis (ADCP). XmAb-2513 can be used for hematologic malignancies like Hodgkin Lymphoma (HL) and Anaplastic Large Cell Lymphoma (ALCL) research .
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Referencia número: HY-P991512

Target:  

Apoptosis

Áreas de investigación:  

Cancer

SGN-30 is a chimeric antibody derived from a mouse antihuman CD30 antibody, AC10, with the variable regions of AC10 and human α 1 heavy chain and κ light chain constant regions. SGN-30 induces apoptosis and cell-cycle arrest in cancer cells. SGN-30 can be used for the study of Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (ALCL) .
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Referencia número: HY-149473
Target:  

Cholinesterase (ChE)

Áreas de investigación:  

Neurological Disease

AChE-IN-39 (Compound 7c) is an AChE inhibitor (IC50: 0.058 μM). AChE-IN-39 has DPPH scavenging activity. AChE-IN-39 improves the cognitive impairment in AlCl3-induced amnesia animal model. AChE-IN-39 can be used for research of Alzheimer's disease .
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Referencia número: HY-177823
Target:  

TNF Receptor

Áreas de investigación:  

Cancer

C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells.
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Referencia número: HY-18030B
No. CAS: 1354545-57-5
Áreas de investigación:  

Others

CEP-28122 mesylate hydrochloride, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK inhibitor with an IC50 value of 1.9 nM. CEP-28122 mesylate hydrochloride has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate hydrochloride has good pharmacodynamic and pharmacokinetic activity. CEP-28122 mesylate hydrochloride can be used for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells .
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Referencia número: HY-P991553

Target:  

TNF Receptor Apoptosis

Áreas de investigación:  

Inflammation/Immunology Cancer

HeFi-1 is a mouse anti-CD30 IgG1 monoclonal antibody. HeFi-1 recognizes the ligand-binding site on CD30. HeFi-1 can inhibit the growth of tumor cells with high expression of CD30. HeFi-1 can induce eosinophil apoptosis. HeFi-1 can be used for researches on cancer or inflammation conditions such as anaplastic large-cell lymphoma (ALCL) and asthma .
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Referencia número: HY-10192R
No. CAS: 761439-42-3
Synonyms: TAE 684 (Standard)
Áreas de investigación:  

Cancer

NVP-TAE 684 (Standard) is the analytical standard of NVP-TAE 684 (HY-10192). This product is intended for research and analytical applications. NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM .
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Referencia número: HY-186338
No. CAS: 845812-90-0
Áreas de investigación:  

Cancer

ALK-IN-39 is an ALK inhibitor. ALK-IN-39 targets anaplastic lymphoma kinase fusion proteins and inhibits NPM-ALK-dependent proliferation. ALK-IN-39 inhibits the proliferation of cells expressing Tel-InsR as well as wild-type hematopoietic cells and anaplastic large cell lymphoma cells. ALK-IN-39 can be used in research on anaplastic large cell lymphoma (ALCL) .
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