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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
APLNR
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "APLNR" in MCE Product Catalog:
Cat. No.: HY-P2271
CAS No.: 1313027-43-8
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Cat. No.: HY-126293
CAS No.: 2227512-85-6
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Apelin agonist 1 is an oral selective apelin agonist AM-2995, a agonist of the APJ (APLNR, angiotensin receptor like-1) receptor, may be used in the treatment of cardiovascular conditions. Apelin agonist 1 is extracted from patent WO 2018097944 (210.0), Example 210.0 .
Cat. No.: HY-147751
CAS No.: 1965244-85-2
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APJ receptor agonist 6 (compound 9) is a potent APJ (apelin receptor) agonist, with Ki of 1.3 μM. APJ receptor agonist 6 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively .
Cat. No.: HY-178982
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Apelin agonist 2 (Compound 35) is an orally active APLNR agonist. Apelin agonist 2 can significantly inhibit the accumulation of cAMP (EC50 = 10 nM). Apelin agonist 2 exhibits a significant improvement in glucose tolerance. Apelin agonist 2 can be used to study metabolic diseases such as diabetes .
Cat. No.: HY-RS00823
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APLNR Human Pre-designed siRNA Set A contains three designed siRNAs for APLNR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00824
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Aplnr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Aplnr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00825
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Aplnr Rat Pre-designed siRNA Set A contains three designed siRNAs for Aplnr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991861
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Cat. No.: HY-183777
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B-007 is an AplnR agonist with G protein-biased signaling (EC50 = 11.6 nM). B-007 activates the G protein pathway while abolishing β-arrestin1 and β-arrestin2 signaling. B-007 serves as a scaffold for development of G protein-biased apelin receptor agonists. B-007 can be used for the research of heart failure .
Cat. No.: HY-P705991
Purity: ≥ 95%, as determined by HPLC.
Synonyms: Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
