4 Results for "

AS1413

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "AS1413" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-10982
CAS No.: 69408-81-7
Purity:  99.92%
Synonyms: AS1413
Target:  

Topoisomerase

Research Areas:  

Cancer

Amonafide is a topoisomerase II inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA.
loading...
    loading...
Cat. No.: HY-10982A
CAS No.: 150091-68-2
Synonyms: AS1413 dihydrochloride
Target:  

Topoisomerase

Research Areas:  

Others

Amonafide dihydrochloride (AS1413 dihydrochloride) is a topoisomerase II (Topo II) inhibitor and DNA intercalator with activity in inducing apoptotic signaling. Amonafide dihydrochloride can inhibit the binding of Topo II to DNA, thereby preventing the synthesis of DNA and RNA. Amonafide dihydrochloride maintains cytotoxic activity in the presence of P-glycoprotein-mediated multidrug resistance (MDR) .
loading...
    loading...
Cat. No.: HY-10982R
CAS No.: 69408-81-7
Synonyms: AS1413 (Standard)
Research Areas:  

Cancer

Amonafide (Standard) is the analytical standard of Amonafide. This product is intended for research and analytical applications. Amonafide is a topoisomerase II inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA.
loading...
    loading...
Cat. No.: HY-118823
CAS No.: 618863-54-0
Synonyms: AS-1413 L-malate
Research Areas:  

Cancer

Amonafide L-malate is a topoisomerase II inhibitor and DNA intercalator that induces Apoptotic signaling by blocking the binding of Topo II to DNA .
loading...
    loading...