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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
Aedes aegypti
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "Aedes aegypti" in MCE Product Catalog:
3
Target:
Research Areas:
Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial, anticandidal and antifungal properties .
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3 Cited Publications
Cat. No.: HY-114633
CAS No.: 901008-62-6
Target:
Research Areas:
VU625 is an inhibitor for potassium channel, that selectively inhibits mosquito Aedes aegypti inward rectifier potassium channel 1 (AeKir), with IC50 of 96.8 nM in HEK293 cell. VU625 can be used in development of insecticide .
2
Category:
Infection Ardisia brevicaulis Diels Phenols Polyphenols Plants Myrsinaceae Disease Research Fields
Target:
2
Research Areas:
Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .
1
Cat. No.: HY-N3097
CAS No.: 18836-52-7
Synonyms: DAQ B1; L-783281; Dimethylasterriquinone
Target:
Insulin Receptor Akt NO Synthase NADPH Oxidase JAK STAT FOXO DNA/RNA Synthesis ERK Flavivirus
Research Areas:
Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology
Demethylasterriquinone B1 (DAQ B1; L-783281) is an orally active insulin receptor (insulin receptor) agonist and AKT activator. By activating AKT, Demethylasterriquinone B1 upregulates the expression and activity of eNOS to increase NO production, while downregulating the expression of the NADPH oxidase subunit p22phox to reduce oxidative stress and improve vascular endothelial dysfunction in hypertensive rats. Demethylasterriquinone B1 combind with an AKT inhibitor targets the insulin signaling pathway to activate two antiviral pathways, RNA interference and JAK/STAT, in mosquitoes, thereby reducing Zika virus infection .
Synonyms: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium
Category:
Cat. No.: HY-W002270
CAS No.: 3681-78-5
Synonyms: Propyl laurate
Target:
Research Areas:
Propyl dodecanoate (Propyl laurate) is a synthetic dodecanoic acid ester, exhibiting biting deterrent activity against Aedes aegypti mosquitoes. Propyl dodecanoate can be used for the research of mosquito-borne disease vectors (Aedes aegypti) .
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Research Areas:
VU041 is a first submicromolar-affinity inhibitor of Anopheles (An.) gambiae and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC50 values of 2.5 μM and 1.7 μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 (IC50 of 12.7 μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function .
Cat. No.: HY-N11654
CAS No.: 22910-86-7
Synonyms: Cardol monoene
Category:
Target:
Cat. No.: HY-W320276
CAS No.: 484-31-1
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Cat. No.: HY-W127493
CAS No.: 506-52-5
Synonyms: Ceryl Alcohol
Cat. No.: HY-W100043
CAS No.: 42822-86-6
Target:
Research Areas:
p-Menthane-3,8-diol is a mosquito repellent derived from hydrated cyclized lemon eucalyptus oil. p-Menthane-3,8-diol exerts repellent effects by preventing laboratory-reared Aedes aegypti from landing/probing and biting on exposed skin. p-Menthane-3,8-diol can be used to repel Aedes aegypti .
Cat. No.: HY-W004285
CAS No.: 1731-86-8
Category:
Natural Products Sterculiaceae Sterculia lychnophera Hance Other Diseases Plants Disease Research Fields
Target:
Cat. No.: HY-W142258
CAS No.: 927-49-1
Target:
Cat. No.: HY-N2976
CAS No.: 35833-62-6
Synonyms: Betulafolianediol 3-acetate; Cabraleadiol 3-acetate
Target:
Cat. No.: HY-W004285R
CAS No.: 1731-86-8
Target:
Cat. No.: HY-116934R
CAS No.: 3158-56-3
Synonyms: Adipostatin A (Standard)
Target:
Cat. No.: HY-W127493R
CAS No.: 506-52-5
Synonyms: Ceryl Alcohol (Standard)
Research Areas:
1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
