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Results for "

Aedes aegypti

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Amyloid-β (2) Autophagy (1) Bacterial (3) Biochemical Assay Reagents (2) Cholinesterase (ChE) (4) Dengue Virus (3) Dihydroorotate Dehydrogenase (2) DNA/RNA Synthesis (2) Endogenous Metabolite (2) Environmental Pollutants (1) ERK (2) Ferroptosis (2) Flavivirus (4) FOXO (1) Glutathione Peroxidase (2) Glutathione S-transferase (1) Heme Oxygenase (HO) (2) IFNAR (1) Influenza Virus (1) Insecticide (13) Insulin Receptor (1) Interleukin Related (1) JAK (1) Keap1-Nrf2 (2) NADPH Oxidase (1) NF-κB (2) NO Synthase (1) Nuclear Factor of activated T Cells (NFAT) (1) Nucleoside Antimetabolite/Analog (1) PAI-1 (2) Parasite (7) Potassium Channel (2) Proton Pump (2) Reference Standards (4) SOD (1) STAT (2) Thrombin (2) Toll-like Receptor (TLR) (2) TRP Channel (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (3) Infection (24) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (2)

By Targets:

Akt (1)

Amyloid-β (2)

Autophagy (1)

Bacterial (3)

Biochemical Assay Reagents (2)

Cholinesterase (ChE) (4)

Dengue Virus (3)

Dihydroorotate Dehydrogenase (2)

DNA/RNA Synthesis (2)

Endogenous Metabolite (2)

Environmental Pollutants (1)

ERK (2)

Ferroptosis (2)

Flavivirus (4)

FOXO (1)

Glutathione Peroxidase (2)

Glutathione S-transferase (1)

Heme Oxygenase (HO) (2)

IFNAR (1)

Influenza Virus (1)

Insecticide (13)

Insulin Receptor (1)

Interleukin Related (1)

JAK (1)

Keap1-Nrf2 (2)

NADPH Oxidase (1)

NF-κB (2)

NO Synthase (1)

Nuclear Factor of activated T Cells (NFAT) (1)

Nucleoside Antimetabolite/Analog (1)

PAI-1 (2)

Parasite (7)

Potassium Channel (2)

Proton Pump (2)

Reference Standards (4)

SOD (1)

STAT (2)

Thrombin (2)

Toll-like Receptor (TLR) (2)

TRP Channel (2)

By Research Areas:

Cancer (5)

Cardiovascular Disease (3)

Infection (24)

Inflammation/Immunology (4)

Metabolic Disease (1)

Neurological Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116144

Picaridin 3 Publications Verification Lcaridin	Environmental Pollutants Parasite	Infection
Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial, anticandidal and antifungal properties .

HY-N3097

Pellitorine	TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB ERK Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .

HY-116934

5-Pentadecylresorcinol 1 Publications Verification Adipostatin A	Insecticide	Infection Cancer
5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC₅₀ of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

HY-107586

Demethylasterriquinone B1 DAQ B1; L-783281; Dimethylasterriquinone	Insulin Receptor Akt NO Synthase NADPH Oxidase JAK STAT FOXO DNA/RNA Synthesis ERK Flavivirus	Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology
Demethylasterriquinone B1 (DAQ B1; L-783281) is an orally active insulin receptor (insulin receptor) agonist and AKT activator. By activating AKT, Demethylasterriquinone B1 upregulates the expression and activity of eNOS to increase NO production, while downregulating the expression of the NADPH oxidase subunit p22phox to reduce oxidative stress and improve vascular endothelial dysfunction in hypertensive rats. Demethylasterriquinone B1 combind with an AKT inhibitor targets the insulin signaling pathway to activate two antiviral pathways, RNA interference and JAK/STAT, in mosquitoes, thereby reducing Zika virus infection .

HY-134891

HMBPP lithium (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium	Nuclear Factor of activated T Cells (NFAT)	Infection Inflammation/Immunology
HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .

HY-B2031

Pyriproxyfen 1 Publications Verification S-31183	Autophagy Parasite	Infection
Pyriproxyfen (S-31183) is a juvenile hormone analog and insect growth regulator. Pyriproxyfen is used in research related to dengue fever and malaria .

HY-W002270

Propyl dodecanoate Propyl laurate	Insecticide	Infection
Propyl dodecanoate (Propyl laurate) is a synthetic dodecanoic acid ester, exhibiting biting deterrent activity against Aedes aegypti mosquitoes. Propyl dodecanoate can be used for the research of mosquito-borne disease vectors (Aedes aegypti) .

HY-118607

VU041	Potassium Channel Parasite	Infection
VU041 is a first submicromolar-affinity inhibitor of *Anopheles (An.) gambiae* and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC₅₀ values of 2.5 μM and 1.7 μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 (IC₅₀ of 12.7 μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function .

HY-B1120

Temephos 2 Publications Verification Temefos	Insecticide Cholinesterase (ChE) Dengue Virus Flavivirus	Infection
Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .

HY-N11654

Bilobol Cardol monoene	Insecticide	Infection Cancer
Bilobol is a potent insecticide against Aedes aegypti with a LC₅₀ of 7.67 mg/L. Bilobol also has antitumor activity .

HY-114633

VU625 2 Publications Verification	Potassium Channel	Others
VU625 is an inhibitor for potassium channel, that selectively inhibits mosquito Aedes aegypti inward rectifier potassium channel 1 (AeKir), with IC₅₀ of 96.8 nM in HEK293 cell. VU625 can be used in development of insecticide .

HY-W013715B

Deoxythymidine-5'-triphosphate trisodium,100 mM Solution,PCR Grade dTTP trisodium,100 mM Solution,PCR Grade	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Others
Deoxythymidine-5'-triphosphate (dTTP) trisodium, 100 mM Solution, PCR Grade is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate trisodium, 100 mM Solution, PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.

HY-W320276

Dill apiole	Endogenous Metabolite Bacterial Parasite	Infection Others
Dill apiole is an aromatic ether, which is an important aroma component in herbs and spices such as dill (Anethum graveolens), parsley (Petroselinum crispum) and basil (Perilla frutescens). Dill apiole exhibits antimicrobial activity against Aspergillus parasiticus and Aedes aegypti .

HY-W127493

1-Hexacosanol Ceryl Alcohol	Biochemical Assay Reagents	Infection
1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes* aegypti and Chironomus riparius*, exerting neurotoxic effects .

HY-W100043

p-Menthane-3,8-diol	Insecticide	Infection
p-Menthane-3,8-diol is an insect repellent. p-Menthane-3,8-diol can be used to repel Aedes aegypti .

HY-W142258

6-Undecanone	Parasite	Infection
6-Undecanone is a ligand of Odorant-binding protein 22 (OBP22) with a weak bind capacity. -Undecanone can be used as a negative control for Aedes aegypti mosquito infection research .

HY-N2976

Cabraleadiol monoacetate Betulafolianediol 3-acetate; Cabraleadiol 3-acetate	Others	Infection
Cabraleadiol monoacetate is a compound isolated from the lichen Pyxine consocians Vainio. Cabraleadiol monoacetate shows mosquito larvicidal activity against the second instar larvae of Aedes aegypti .

HY-116934R

5-Pentadecylresorcinol (Standard) Adipostatin A (Standard)	Reference Standards Others	Infection Cancer
5-Pentadecylresorcinol (Standard) is the analytical standard of 5-Pentadecylresorcinol. This product is intended for research and analytical applications. 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

HY-W127493R

1-Hexacosanol (Standard) Ceryl Alcohol (Standard)	Biochemical Assay Reagents Reference Standards	Infection
1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects.

HY-B1120R

Temephos (Standard) Temefos (Standard)	Reference Standards Insecticide Cholinesterase (ChE) Dengue Virus Flavivirus	Infection
Temephos (Standard) is the analytical standard of Temephos. This product is intended for research and analytical applications. Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .

HY-B1120S

Temephos-d12 Temefos-d₁₂	Cholinesterase (ChE) Dengue Virus Flavivirus Parasite	Infection
Temephos-d₁₂ is the deuterium labeled Temephos. Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .

HY-N3097R

Pellitorine (Standard)	Reference Standards TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.

HY-N13754

Leptostachyol acetate	Parasite	Infection
Leptostachyol acetate is a lignan compound that can be isolated from the roots of Phryma leptostachya var. asiatica. Leptostachyol acetate exhibits larvicidal activity against mosquito larvae, with LC₅₀ values of 0.41, 2.1, and 2.3 ppm against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi, respectively. Leptostachyol acetate can be used for research on mosquito larval control .

HY-180460

SCPI-1	Insecticide	Others
SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC₅₀ = 0.347 µM; AeSCP-x IC₅₀ = 0.527 µM). SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC₅₀ of 5.53 µM in Aag-2 cells). SCPI-1 shows insecticidal activity against Aedes aegypti with a LD₅₀ of 4.8 µM .

HY-180500

SCPI-3	Insecticide	Others
SCPI-3 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC₅₀ = 0.159 µM; AeSCP-x IC₅₀ = 0.285 µM). SCPI-3 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC₅₀ of 3.09 µM in Aag-2 cells). SCPI-3 shows insecticidal activity against Aedes aegypti with a LD₅₀ of 12.3 µM .

HY-N17963

Cappariloside A	Glutathione S-transferase Influenza Virus Interleukin Related IFNAR STAT	Infection
Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection .

HY-180141

AF03	Insecticide Cholinesterase (ChE) SOD	Infection
AF03 is a larvicide against Aedes aegypti Vector Larvae with a LC₅₀ of 41.6 μg/mL. AF03 binds stably to the sterol carrier protein-2 (AeSCP-2) of Aedes aegypti, interfering with lipid metabolism in larvae. AF03 can increase acetylcholinesterase (AChE) activity in the zebrafish brain, slightly elevate catalase (CAT) activity in the liver and heart, and increased superoxide dismutase (SOD) activity in the brain. AF03 can be used for the research of arboviruses infection, such as Dengue .

HY-N11234A

(Z)-γ-Bisabolene	Insecticide	Infection
(Z)-γ-Bisabolene is a monocyclic bisabolane-type sesquiterpene hydrocarbon found in the essential oil of Galinsoga parviflora, acting as a mosquito larvicide and oviposition deterrent. (Z)-γ-Bisabolene induces acute toxicity in larvae of six mosquito species. (Z)-γ-Bisabolene deters oviposition in gravid females of six mosquito species. (Z)-γ-Bisabolene can be used for the research of malaria, dengue, japanese encephalitis, zika virus .

HY-N14120

Opoponax oil Opopanax oil	Insecticide	Others
Opoponax oil is an effective insecticide against mosquito larvae .

Cat. No.	Product Name	Type

HY-W013715B

Deoxythymidine-5'-triphosphate trisodium,100 mM Solution,PCR Grade dTTP trisodium,100 mM Solution,PCR Grade	Biochemical Assay Reagents
Deoxythymidine-5'-triphosphate (dTTP) trisodium, 100 mM Solution, PCR Grade is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate trisodium, 100 mM Solution, PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.

HY-W127493

1-Hexacosanol Ceryl Alcohol	Biochemical Assay Reagents
1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes* aegypti and Chironomus riparius*, exerting neurotoxic effects .

HY-W127493R

1-Hexacosanol (Standard) Ceryl Alcohol (Standard)	Biochemical Assay Reagents
1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects.

1-Hexacosanol (Standard)

Ceryl Alcohol (Standard)

Biochemical Assay Reagents

1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol can be used as an inhibitor of acetylcholinesterase (AChE). 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3097

Pellitorine	Alkaloids Classification of Application Fields Other Alkaloids Piperaceae Plants Disease Research Fields Piper nigrum Linn. Biological Pesticide Research Source Classification Cancer Agricultural Research	TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB ERK Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .

HY-116934

5-Pentadecylresorcinol 1 Publications Verification Adipostatin A	Infection Structural Classification Ardisia brevicaulis Diels Classification of Application Fields Phenols Polyphenols Plants Myrsinaceae Disease Research Fields Source Classification	Insecticide
5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC₅₀ of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

HY-134891

HMBPP lithium (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium	Natural Products Microorganisms Source Classification	Nuclear Factor of activated T Cells (NFAT)
HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .

HY-N11654

Bilobol Cardol monoene	Ginkgoaceae Phenols Polyphenols Plants Ginkgo biloba Source Classification	Insecticide
Bilobol is a potent insecticide against Aedes aegypti with a LC₅₀ of 7.67 mg/L. Bilobol also has antitumor activity .

HY-W320276

Dill apiole	Structural Classification Natural Products Labiatae Plants Helenium arizonicum S.F.Blake Source Classification	Endogenous Metabolite Bacterial Parasite
Dill apiole is an aromatic ether, which is an important aroma component in herbs and spices such as dill (Anethum graveolens), parsley (Petroselinum crispum) and basil (Perilla frutescens). Dill apiole exhibits antimicrobial activity against Aspergillus parasiticus and Aedes aegypti .

HY-W142258

6-Undecanone	Structural Classification Natural Products Umbelliferae Plants Echinacea angustifolia DC. Source Classification	Parasite
6-Undecanone is a ligand of Odorant-binding protein 22 (OBP22) with a weak bind capacity. -Undecanone can be used as a negative control for Aedes aegypti mosquito infection research .

HY-N2976

Cabraleadiol monoacetate Betulafolianediol 3-acetate; Cabraleadiol 3-acetate	Infection Triterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification	Others
Cabraleadiol monoacetate is a compound isolated from the lichen Pyxine consocians Vainio. Cabraleadiol monoacetate shows mosquito larvicidal activity against the second instar larvae of Aedes aegypti .

HY-116934R

5-Pentadecylresorcinol (Standard) Adipostatin A (Standard)	Structural Classification Ardisia brevicaulis Diels Phenols Polyphenols Plants Myrsinaceae Source Classification	Reference Standards Others
5-Pentadecylresorcinol (Standard) is the analytical standard of 5-Pentadecylresorcinol. This product is intended for research and analytical applications. 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

HY-N3097R

Pellitorine (Standard)	Alkaloids Other Alkaloids Piperaceae Plants Piper nigrum Linn. Source Classification	Reference Standards TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.

HY-N13754

Leptostachyol acetate	Structural Classification Lignans Phryma leptostachya subsp. asiatica (Hara)Kitamura Phrymaceae Phenylpropanoids Plants Source Classification	Parasite
Leptostachyol acetate is a lignan compound that can be isolated from the roots of Phryma leptostachya var. asiatica. Leptostachyol acetate exhibits larvicidal activity against mosquito larvae, with LC₅₀ values of 0.41, 2.1, and 2.3 ppm against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi, respectively. Leptostachyol acetate can be used for research on mosquito larval control .

HY-N17963

Cappariloside A	Structural Classification Alkaloids Capparaceae Plants Maerua siamensis (Kurz) Pax Indole Alkaloids Source Classification	Glutathione S-transferase Influenza Virus Interleukin Related IFNAR STAT
Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection .

HY-N11234A

(Z)-γ-Bisabolene	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Swartzia polyphylla DC. Source Classification	Insecticide
(Z)-γ-Bisabolene is a monocyclic bisabolane-type sesquiterpene hydrocarbon found in the essential oil of Galinsoga parviflora, acting as a mosquito larvicide and oviposition deterrent. (Z)-γ-Bisabolene induces acute toxicity in larvae of six mosquito species. (Z)-γ-Bisabolene deters oviposition in gravid females of six mosquito species. (Z)-γ-Bisabolene can be used for the research of malaria, dengue, japanese encephalitis, zika virus .

HY-N14120

Opoponax oil Opopanax oil	Natural Products Apiaceae Opopanax hispidus Plants Source Classification	Insecticide
Opoponax oil is an effective insecticide against mosquito larvae .

Cat. No.	Product Name	Chemical Structure

HY-B1120S

Temephos-d12

Temephos-d₁₂ is the deuterium labeled Temephos. Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .

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