Bilobol (Synonyms: Cardol monoene)

Cat. No.: HY-N11654 Purity: 97.1%: Data Sheet
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Bilobol is a potent insecticide against Aedes aegypti with a LC₅₀ of 7.67 mg/L. Bilobol also has antitumor activity.

For research use only. We do not sell to patients.

Bilobol Chemical Structure

CAS No. : 22910-86-7

Size	Stock	Quantity
Solvent
500 μg (15.70 mM * 100 μL in Acetonitrile)	In-stock	Estimated Time of Arrival: December 31
Solvent
1 mg (15.70 mM * 200 μL in Acetonitrile)	In-stock	Estimated Time of Arrival: December 31

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Description

Bilobol is a potent insecticide against Aedes aegypti with a LC₅₀ of 7.67 mg/L. Bilobol also has antitumor activity^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	1.85 μM Compound: 6	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 17125236]
A549	IC₅₀	1.76 μM Compound: 6	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 17125236]
A549	IC₅₀	> 50 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human A549 cells after 2 days by SRB assay Growth inhibition of human A549 cells after 2 days by SRB assay	[PMID: 9677265]
BGC-823	IC₅₀	1.8 μM Compound: 6	Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay	[PMID: 17125236]
Bel-7402	IC₅₀	1.86 μM Compound: 6	Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay	[PMID: 17125236]
CCD-18Co	IC₅₀	33.63 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human CCD-18Co cells after 2 days by SRB assay Growth inhibition of human CCD-18Co cells after 2 days by SRB assay	[PMID: 9677265]
HCT-15	IC₅₀	14.88 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human HCT15 cells after 2 days by SRB assay Growth inhibition of human HCT15 cells after 2 days by SRB assay	[PMID: 9677265]
HCT-8	IC₅₀	1.8 μM Compound: 6	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 17125236]
HT1197	IC₅₀	8.43 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human HT1197 cells after 2 days by SRB assay Growth inhibition of human HT1197 cells after 2 days by SRB assay	[PMID: 9677265]
MCF7	IC₅₀	5.68 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human MCF7 cells after 2 days by SRB assay Growth inhibition of human MCF7 cells after 2 days by SRB assay	[PMID: 9677265]
SK-OV-3	IC₅₀	23.4 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human SKOV3 cells after 2 days by SRB assay Growth inhibition of human SKOV3 cells after 2 days by SRB assay	[PMID: 9677265]

Molecular Weight

318.49

Formula

C₂₁H₃₄O₂

CAS No.

22910-86-7

Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC1=CC(CCCCCCC/C=C\CCCCCC)=CC(O)=C1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 97.1%

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Data Sheet (260 KB) SDS (252 KB)

COA (238 KB)

Handling Instructions (2659 KB)

References

[1]. Itokawa H, et al. Antitumor principles from Ginkgo biloba L. Chem Pharm Bull (Tokyo). 1987 Jul;35(7):3016-20. [Content Brief]

[2]. Schulte HL, et al. Degradation evaluation and toxicity profile of bilobol, a promising eco-friendly larvicide. Chemosphere. 2021 Jan;263:128323. [Content Brief]

Bilobol Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bilobol22910-86-7Cardol monoeneInsecticideAntitumorAedes aegyptiInhibitorinhibitorinhibit

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Bilobol (Synonyms: Cardol monoene)

Bilobol Related Antibodies

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