Bilobol
Based on 1 Customer Validation
Bilobol is a potent insecticide against Aedes aegypti with a LC50 of 7.67 mg/L. Bilobol also has antitumor activity.
For research use only. We do not sell to patients.
- Purity : 97.1%
- CAS No.: 22910-86-7
- Formula: C21H34O2
- Molecular Weight:318.49
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Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
1.85 μM
Compound: 6
|
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
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[PMID: 17125236] |
| A549 | IC50 |
>50 μg/mL
Compound: 8, bilobol C15:1
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Growth inhibition of human A549 cells after 2 days by SRB assay
Growth inhibition of human A549 cells after 2 days by SRB assay
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[PMID: 9677265] |
| A549 | IC50 |
1.76 μM
Compound: 6
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Cytotoxicity against human A549 cells after 96 hrs by MTT assay
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
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[PMID: 17125236] |
| Bel-7402 | IC50 |
1.86 μM
Compound: 6
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Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay
Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay
|
[PMID: 17125236] |
| BGC-823 | IC50 |
1.8 μM
Compound: 6
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Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay
Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay
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[PMID: 17125236] |
| CCD-18Co | IC50 |
33.63 μg/mL
Compound: 8, bilobol C15:1
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Growth inhibition of human CCD-18Co cells after 2 days by SRB assay
Growth inhibition of human CCD-18Co cells after 2 days by SRB assay
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[PMID: 9677265] |
| HCT-15 | IC50 |
14.88 μg/mL
Compound: 8, bilobol C15:1
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Growth inhibition of human HCT15 cells after 2 days by SRB assay
Growth inhibition of human HCT15 cells after 2 days by SRB assay
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[PMID: 9677265] |
| HCT-8 | IC50 |
1.8 μM
Compound: 6
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Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
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[PMID: 17125236] |
| HT1197 | IC50 |
8.43 μg/mL
Compound: 8, bilobol C15:1
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Growth inhibition of human HT1197 cells after 2 days by SRB assay
Growth inhibition of human HT1197 cells after 2 days by SRB assay
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[PMID: 9677265] |
| MCF7 | IC50 |
5.68 μg/mL
Compound: 8, bilobol C15:1
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Growth inhibition of human MCF7 cells after 2 days by SRB assay
Growth inhibition of human MCF7 cells after 2 days by SRB assay
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[PMID: 9677265] |
| SK-OV-3 | IC50 |
23.4 μg/mL
Compound: 8, bilobol C15:1
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Growth inhibition of human SKOV3 cells after 2 days by SRB assay
Growth inhibition of human SKOV3 cells after 2 days by SRB assay
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[PMID: 9677265] |
Chemical Information
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CAS No. 22910-86-7
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Appearance Liquid
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Molecular Weight 318.49
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Formula C21H34O2
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Color Colorless to light yellow
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SMILES
OC1=CC(CCCCCCC/C=C\CCCCCC)=CC(O)=C1
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Synonyms
Cardol monoene
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Protocols
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Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.
Purity & Documentation
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Data Sheet (260 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bilobol Related Classifications
HY-N11654 Related Classifications
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