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Cat. No.: HY-N11654

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Bilobol

(Synonyms: Cardol monoene)

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Bilobol is a potent insecticide against Aedes aegypti with a LC₅₀ of 7.67 mg/L. Bilobol also has antitumor activity.

For research use only. We do not sell to patients.

Purity: 97.1%
CAS No.: 22910-86-7
Formula: C₂₁H₃₄O₂
Molecular Weight:318.49

Storage:

Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Bilobol Chemical Structure

CAS No.: 22910-86-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Bilobol is a potent insecticide against Aedes aegypti with a LC₅₀ of 7.67 mg/L. Bilobol also has antitumor activity^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
A2780	IC₅₀	1.85 μM Compound: 6	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 17125236]
A549	IC₅₀	>50 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human A549 cells after 2 days by SRB assay Growth inhibition of human A549 cells after 2 days by SRB assay	[PMID: 9677265]
A549	IC₅₀	1.76 μM Compound: 6	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 17125236]
Bel-7402	IC₅₀	1.86 μM Compound: 6	Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay Cytotoxicity against human Bel-7402 cells after 96 hrs by MTT assay	[PMID: 17125236]
BGC-823	IC₅₀	1.8 μM Compound: 6	Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC-823 cells after 96 hrs by MTT assay	[PMID: 17125236]
CCD-18Co	IC₅₀	33.63 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human CCD-18Co cells after 2 days by SRB assay Growth inhibition of human CCD-18Co cells after 2 days by SRB assay	[PMID: 9677265]
HCT-15	IC₅₀	14.88 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human HCT15 cells after 2 days by SRB assay Growth inhibition of human HCT15 cells after 2 days by SRB assay	[PMID: 9677265]
HCT-8	IC₅₀	1.8 μM Compound: 6	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 17125236]
HT1197	IC₅₀	8.43 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human HT1197 cells after 2 days by SRB assay Growth inhibition of human HT1197 cells after 2 days by SRB assay	[PMID: 9677265]
MCF7	IC₅₀	5.68 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human MCF7 cells after 2 days by SRB assay Growth inhibition of human MCF7 cells after 2 days by SRB assay	[PMID: 9677265]
SK-OV-3	IC₅₀	23.4 μg/mL Compound: 8, bilobol C15:1	Growth inhibition of human SKOV3 cells after 2 days by SRB assay Growth inhibition of human SKOV3 cells after 2 days by SRB assay	[PMID: 9677265]

Chemical Information

CAS No. 22910-86-7
Appearance Liquid
Molecular Weight 318.49
Formula C₂₁H₃₄O₂
Color Colorless to light yellow
SMILES

OC1=CC(CCCCCCC/C=C\CCCCCC)=CC(O)=C1
Synonyms

Cardol monoene
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (260 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Itokawa H, et al. Antitumor principles from Ginkgo biloba L. Chem Pharm Bull (Tokyo). 1987 Jul;35(7):3016-20. [Content Brief]

[2]. Schulte HL, et al. Degradation evaluation and toxicity profile of bilobol, a promising eco-friendly larvicide. Chemosphere. 2021 Jan;263:128323. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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