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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
AtHPPD
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "AtHPPD" in MCE Product Catalog:
Cat. No.: HY-155135
CAS No.: 2950190-99-3
HPPD-IN-1 (compound II-3) is a HPPD inhibitor. HPPD-IN-1 shows inhibitory activity of Arabidopsis thaliana HPPD (AtHPPD) with an IC50 value of 0.248 μM, which was superior to that of mesotrione (HY-12853) (0.283 μM) in vitro. HPPD-IN-1 shows excellent herbicidal activity against broadleaf and monocotyledonous weeds .
Cat. No.: HY-187378
CAS No.: 3124322-98-8
HPPD-IN-12 is an inhibitor of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD), with an IC50 of 27.8 μM and a Kd of 1.535 μM. HPPD-IN-12 binds to AtHPPD via Fe 2+ coordination, π-π interactions and hydrogen bonds. HPPD-IN-12 can be used in herbicide-related research .
Cat. No.: HY-187374
HPPD-IN-11 is an inhibitor of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD), with a Ki value of 0.016 μM, and exhibits herbicidal activity. HPPD-IN-11 enhances π-π interactions with Phe360 and Phe403 in the active site of AtHPPD, thereby strengthening its enzyme-binding ability. HPPD-IN-11 can be used in studies related to weed damage .
Cat. No.: HY-189229
Target:
Research Areas:
HPPD-IN-16 is a potent HPPD inhibitor with an IC50 of 0.146 μM against AtHPPD. HPPD-IN-16 blocks HPPD enzymatic activity, interferes with the biosynthesis of plastoquinone and tocopherol, and causes plant death due to albinism resulting from the lack of photosynthetic pigments. HPPD-IN-16 can be used in herbicide research .
Cat. No.: HY-189092
CAS No.: 2776994-70-6
HPPD-IN-14 is an inhibitor of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD), with an IC50 of 0.188 μM and a Ki of 0.0077 μM. HPPD-IN-14 forms a stable complex through coordination with the active-site metal ion and multiple non-covalent interactions, thereby inhibiting the growth of target weeds, and exhibits high safety to wheat. HPPD-IN-14 can be used in herbicide-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
