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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
B-CLL cells
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "B-CLL cells" in MCE Product Catalog:
49
49 Publications Verification
Synonyms: Mitozantrone; NSC 301739
Category:
Target:
49
49 Publications Verification
Synonyms: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride
1
1 Cited Publications
Synonyms: Delphinidin 3-O-glucoside chloride; Delphinidin 3-O-β-glucoside chloride
Cat. No.: HY-108052R
CAS No.: 6906-38-3
Synonyms: Delphinidin 3-O-glucoside chloride (Standard); Delphinidin 3-O-β-glucoside chloride (Standard)
Target:
Cat. No.: HY-13502B
CAS No.: 70711-41-0
Synonyms: Mitozantrone diacetate; NSC 301739 diacetate
Cat. No.: HY-13502AR
CAS No.: 70476-82-3
Synonyms: Mitozantrone dihydrochloride (Standard); NSC 301739 dihydrochloride (Standard)
Category:
Cat. No.: HY-13502AS
Synonyms: Mitozantrone-d8dihydrochloride; NSC 301739-d8 dihydrochloride
Cat. No.: HY-13502AS1
Synonyms: Mitozantrone-d8 hydrochloride; NSC 301739-d8 hydrochloride
Cat. No.: HY-13502R
CAS No.: 65271-80-9
Synonyms: Mitozantrone (Standard); NSC 301739 (Standard)
Category:
Cat. No.: HY-113382R
CAS No.: 616-04-6
Synonyms: 1-Methylhydantoin (Standard)
Category:
Cat. No.: HY-P12219
Synonyms: OP449
Research Areas:
COG449 is a cell-penetrating peptide that binds to SET, prevents the formation of the SET-PP2A complex, and restores PP2A phosphatase activity. COG449 decreases the phosphorylation levels of AKT 308, ERK1/2, NFkB p65, and c-MYC S62, and reduces c-MYC stability and target gene expression. COG449 induces apoptosis, autophagy, and histone H3 hyperacetylation, and decreases the levels of SET, CIP2A, SETBP1, and Mcl-1. COG449 reduces cancer cell viability and decreases tumor mass in xenograft models. COG449 can be used for research on various cancers such as oral squamous cell carcinoma, T-cell acute lymphoblastic leukemia, B-CLL, non-Hodgkin lymphoma, and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
