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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Bpin
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Bpin" in MCE Product Catalog:
Cat. No.: HY-79444
CAS No.: 73183-34-3
Cat. No.: HY-W998267
CAS No.: 2698398-71-7
Target:
Research Areas:
Desamino lenalidomide-Bpin is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-Bpin can be linked to a target protein ligand via a linker to form a PROTAC.
Cat. No.: HY-W006635
CAS No.: 1049004-32-1
Synonyms: Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate
Target:
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Bpin-Cyclohexene-COOEt (Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate) is a PROTAC Linker, which can be used in studies related to PROTAC synthesis, such as serving as the core structure of PROTAC SMARCA2/4 degrader-6 (HY-159457) .
Cat. No.: HY-170472
CAS No.: 2375174-10-8
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Bpin-Bedaquiline (compound 2) is a boronic ester precursor of Bedaquiline (HY-14881). Bpin-Bedaquiline can react with H476Br to synthesize 76Br-Bedaquiline .
Cat. No.: HY-163952
Research Areas:
(S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-22 (HY-163875) .
Cat. No.: HY-163950
Research Areas:
(S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-20 (HY-163873) .
Cat. No.: HY-159684
Target:
Research Areas:
3,8-Diazabicyclo[3.2.1]octane-pyrimidine-piperidine-cyclohexene-Bpin is a PROTAC linker. 3,8-Diazabicyclo[3.2.1]octane-pyrimidine-piperidine-cyclohexene-Bpin can be used in the synthesis PROTAC SMARCA2/4-degrader-30 (HY-162748) .
Cat. No.: HY-W063924
CAS No.: 1166829-70-4
Synonyms: Ethyl-2-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3- enyl)acetate
Target:
Research Areas:
Bpin-Cyclohexene-C-COOEt is a PROTAC linker. Bpin-Cyclohexene-C-COOEt can be used in synthesis PROTAC SMARCA2/4-degrader-8 (HY-159460) .
Cat. No.: HY-159682
Target:
Research Areas:
3,8-Diazabicyclo[3.2.1]octane-4-pyrimidine-piperidine-cyclohexene-Bpin is a PROTAC linker. 3,8-Diazabicyclo[3.2.1]octane-4-pyrimidine-piperidine-cyclohexene-Bpin can be used in the synthesis PROTAC SMARCA2/4-degrader-29 (HY-162743) .
Cat. No.: HY-159550
Research Areas:
SMARCA2/4-ligand-Linker Conjugate-5 is an E3 ligase ligand-linker conjugate.
Cat. No.: HY-159546
Research Areas:
SMARCA2/4-ligand-Linker Conjugate-2 is an E3 ligase ligand-linker conjugate.
Cat. No.: HY-159548
Research Areas:
SMARCA2/4-ligand-Linker Conjugate-3 is an E3 ligase ligand-linker conjugate.
Cat. No.: HY-159549
Research Areas:
SMARCA2/4-ligand-Linker Conjugate-4 is an E3 ligase ligand-linker conjugate.
Cat. No.: HY-W244282
CAS No.: 2229725-98-6
Target:
Research Areas:
Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
Cat. No.: HY-163954
Research Areas:
(S,R,S)-AHPC-Ala-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S,R,S)-AHPC-Ala-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-23 (HY-163876) .
Cat. No.: HY-174356
CAS No.: 2816115-88-3
Target:
Research Areas:
Boc-(2,6-DMP)-THP-Bpin is a PROTAC linker that can be used in the synthesis of PROTAC HPK1 Degrader-4 (HY-174135). PROTAC HPK1 Degrader-4 is a selective and orally active PROTAC HPK1 degrader with a DC50 of 3.16 nM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
