Bpin-Cyclohexene-COOEt
Based on 1 Customer Validation
Bpin-Cyclohexene-COOEt (Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate) is a PROTAC Linker, which can be used in studies related to PROTAC synthesis, such as serving as the core structure of PROTAC SMARCA2/4 degrader-6 (HY-159457).
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 1049004-32-1
- Formula: C15H25BO4
- Molecular Weight:280.17
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Storage:Pure form -20°C, 3 years
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Bpin-Cyclohexene-COOEt serves as the linker moiety of PROTAC SMARCA2/4 degrader-6 (HY-159457), a PROTAC degrader targeting SMARCA2 and SMARCA4 with a DC50 of < 100 nM for both proteins, which is applicable to cancer-related research[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1049004-32-1
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Appearance Liquid (Density: 1.036±0.10 g/cm3)
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Molecular Weight 280.17
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Formula C15H25BO4
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Color Colorless to light yellow
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SMILES
CC1(C)C(C)(C)OB(C2=CCC(C(OCC)=O)CC2)O1
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Synonyms
Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years * The compound is unstable in solutions, freshly prepared is recommended.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bpin-Cyclohexene-COOEt Related Classifications
HY-W006635 Related Classifications
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