7 Results for "

CORM

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "CORM" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-109804
CAS No.: 1001015-18-4
Purity:  98.27%
Research Areas:  

Inflammation/Immunology

CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis .
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4
4 Cited Publications
Cat. No.: HY-100581
CAS No.: 475473-26-8
Purity:  ≥97.0%
Research Areas:  

Inflammation/Immunology

CORM-3, a carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. CORM-3 reduces NLRP3 inflammasome activation .
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4
4 Cited Publications
Cat. No.: HY-W033577
CAS No.: 22594-69-0
Synonyms: CORM-2
Tricarbonyldichlororuthenium(II) dimer (CORM-2) is a CO-releasing molecule. Tricarbonyldichlororuthenium(II) dimer exhibits anti-inflammatory, antioxidant, and gastric mucosa-protective activities. Additionally, Tricarbonyldichlororuthenium(II) dimer has CO-independent functional effects on multiple potassium channels .
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Cat. No.: HY-W782399
CAS No.: 17363-08-5
Synonyms: Sodium boranocarbonate
CORM-A1 (Sodium boranocarbonate) is a water-soluble carbon monoxide (CO) releasing molecule that facilitates the investigation of CO's impact on cellular systems. As CO is generated from heme degradation by the enzyme heme oxygenase, it serves as a crucial gaseous signaling mediator in mammalian cells. CORM-A1 not only exhibits anti-oxidant and anti-inflammatory properties but also regulates CO release in a manner dependent on pH and temperature, promoting mild vasorelaxation and hypotension. Furthermore, CORM-A1 has been shown to provide cytoprotection in primary cultures of astrocytes under oxidative stress while also enhancing autophagy due to its boron-containing composition.
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Cat. No.: HY-143618
CAS No.: 2892235-54-8
Purity:  99.62%
Research Areas:  

Cancer

photoCORM-2 (compound 3) is a single carbon monoxide releasing molecule (CORM). photoCORM-2 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-2 has anti-tumor activity .
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Cat. No.: HY-143617
CAS No.: 2892235-56-0
Target:  

Photosensitizer

Research Areas:  

Cancer

photoCORM-1 (compound 8) is a combinatorial carbon monoxide releasing molecule (CORM). photoCORM-1 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach. photoCORM-1 has anti-tumor antivity .
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Cat. No.: HY-142955
CAS No.: 2892235-55-9
Research Areas:  

Cancer

Dual photoCORM 1 (compound 5) is metal-free, photochemically active dual CORM. Dual photoCORM 1 exhibits good cellular uptake and real-time monitoring ability of CO uncaging by a color change approach in cancerous B16F10 cells .
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