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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
COX-2 mRNA
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "COX-2 mRNA" in MCE Product Catalog:
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4
4 Cited Publications
Cat. No.: HY-N0908
CAS No.: 186763-78-0
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Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia .
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Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae Cancer
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Alkaloids Piperidine Alkaloids Zea mays L. Pyrrole Alkaloids Gramineae Plants Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-14837
CAS No.: 201349-37-3
Synonyms: Enisamium iodide
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Amizon is an orally effective antiviral and anti-inflammatory agent. Amizon inhibits influenza virus replication and restricts viral RNA synthesis. Amizon reduces the mRNA expression of COX-1, COX-2, NF-κB, TGF1β, IL-1 and IL-6, and stimulates the secretion and mRNA expression of IL-10. Amizon inhibits the oxidative activity of macrophages and possesses antioxidant and free radical-scavenging activities. Amizon is applicable to research related to influenza and acute respiratory viral infections .
Cat. No.: HY-N7688
CAS No.: 114420-67-6
Cat. No.: HY-W419589
CAS No.: 16545-23-6
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Xanthomicrol is extracted from the resin of the plant called Chinese bellflower (a member of the Scrophulariaceae family) and is a monoamine oxidase (MAOs) inhibitor. Xanthomicrol has anti-tumor and anti-inflammatory properties, with IC50 values of 0.88 and 1.69 μg/mL in HL60 and K562 cells. Xanthomicrol's the main metabolite of 5DT in mouse colon, and it can reduce levels of iNOS protein and mRNA, as well as COX-2 protein levels. Additionally, Xanthomicrol decreases the production of the pro-inflammatory cytokine IL-1β and induces the expression of the antioxidant enzyme HO-1 .
Cat. No.: HY-B0084R
CAS No.: 65928-58-7
Synonyms: STS 557 (Standard)
Research Areas:
Dienogest (Standard) is the analytical standard of Dienogest. This product is intended for research and analytical applications. Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia .
Cat. No.: HY-N0811
CAS No.: 139051-27-7
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Liliaceae Anemarrhena asphodeloides Bunge Plants Disease Research Fields Inflammation/Immunology Steroids
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Cat. No.: HY-129113R
CAS No.: 20562-03-2
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Cat. No.: HY-N0908R
CAS No.: 186763-78-0
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Cat. No.: HY-171251
CAS No.: 1113116-62-3
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RGS10 modulator-1 (compound 15) is a potent RGS10 modulator. RGS10 modulator-1 significantly reverses IFNγ-induced RGS10 protein and mRNA expression. RGS10 modulator-1 reverse the IFNγ-induced COX-2 mRNA and iNOS expression .
Cat. No.: HY-177643
CAS No.: 1152798-49-6
Lixadesiran is a siRNA in STP705. It targets to COX-2. STP705 is composed of 2 siRNA oligonucleotides (Pixofisiran and Lixadesiran) that individually target TGF-β1 and COX-2 mRNA.
Cat. No.: HY-177643A
Lixadesiran sodium is a siRNA in STP705. It targets to COX-2. STP705 is composed of 2 siRNA oligonucleotides (Pixofisiran and Lixadesiran) that individually target TGF-β1 and COX-2 mRNA.
Cat. No.: HY-115976
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COX-2-IN-10 is a potent COX-2 inhibitor. COX-2-IN-10 inhibits the production of PGE2 in concentration dependent manner (IC50=2.54 µM). COX-2-IN-10 inhibits the expression of iNOS and COX-2 on mRNA and protein level . COX-2-IN-10 inhibits the production of IL-6, TNF-α and IL-1β .
Cat. No.: HY-177657
CAS No.: 1152798-48-5
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Pixofisiran is a siRNA in STP705. It targets to TGF‐β1. STP705 is composed of 2 siRNA oligonucleotides (Pixofisiran and Lixadesiran) that individually target TGF-β1 and COX-2 mRNA.
Cat. No.: HY-177657A
Target:
Research Areas:
Pixofisiran sodium is a siRNA in STP705. It targets to TGF‐β1. STP705 is composed of 2 siRNA oligonucleotides (Pixofisiran and Lixadesiran) that individually target TGF-β1 and COX-2 mRNA.
Cat. No.: HY-137957
CAS No.: 1639810-67-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
