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Cdc48

" in MedChemExpress (MCE) Product Catalog:

By Targets:	p97 (2) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (2)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Targets Recommended: p97 Cdc42-binding kinase Ack1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-139606

VCP/p97 inhibitor-1	p97	Cancer
VCP/p97 inhibitor-1 is a potent inhibitor of VCP/p97 (also called Cdc48, CDC-. 48, or Ter94) with an IC₅₀ of 54.7 nM. VCP/p97 inhibitor-1 causes the dysregulation of protein homeostasis and disturbs the degradation of misfolded polypeptides by the ubiquitin-proteasome system (UPS) .

HY-RS15621

VCP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
VCP Human Pre-designed siRNA Set A contains three designed siRNAs for VCP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

VCP Human Pre-designed siRNA Set A VCP Human Pre-designed siRNA Set A

HY-RS15622

Vcp Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Vcp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vcp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Vcp Mouse Pre-designed siRNA Set A Vcp Mouse Pre-designed siRNA Set A

HY-118460

ACJI-99C VCP/p97-IN-PPA	p97	Cancer
ACJI-99C (VCP/p97-IN-PPA) is a selective covalent p97/VCP ATPase inhibitor with an IC₅₀ value of 0.6 μM. ACJI-99C binds with p97 active site residues to block ATPase activity. ACJI-99C irreversibly blocks degradation of p97-dependent protein in cells. ACJI-99C inhibits proliferation of cancer cells, including p97 inhibitor-resistant lines. ACJI-99C can be used for the research of colorectal cancer .

Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4) Rat (2) Mouse (4)
Application:	IHC-P (2) ICC/IF (4) IP (2) IHC-F (2) WB (4) FC (2) ELISA (2)
Isotype:	IgG (2) IgG1 (2)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84401

	VCP Antibody (YA4098) p97; TERA; Cdc48; FTDALS6	WB, ICC/IF, FC, ELISA	Human, Mouse
	VCP Antibody (YA4098) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to VCP.

HY-P84401A

	VCP Antibody (YA4098)(PBS only) p97; TERA; Cdc48; FTDALS6	WB, ICC/IF, FC, ELISA	Human, Mouse
	VCP Antibody (YA4098) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to VCP.

HY-P82630

	VCP Antibody (YA2375) 15S Mg(2+) ATPase p97 subunit; ALS14; ATPase p97; Cdc48; IBMPFD; p97; TER ATPase; TERA; VCP; Yeast Cdc48p homolog	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	VCP Antibody (YA2375) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCP.

HY-P82630A

	VCP Antibody (YA2375)(PBS only) 15S Mg(2+) ATPase p97 subunit; ALS14; ATPase p97; Cdc48; IBMPFD; p97; TER ATPase; TERA; VCP; Yeast Cdc48p homolog	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	VCP Antibody (YA2375) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCP.

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VCP Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
VCP Human Pre-designed siRNA Set A contains three designed siRNAs for VCP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Vcp Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Vcp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vcp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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