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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
Cer1
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "Cer1" in MCE Product Catalog:
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1 Cited Publications
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P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor wirh an IC50 of 0.5 μM. P053 acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle. Whole-body adiposity regulator [1].
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Synonyms: MBR 12325
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Mefluidide is a potent inhibitor of KCS6, CER60 and CER1 enzymes and can be used in herbicide research [1].
Cat. No.: HY-RS02532
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CER1 Human Pre-designed siRNA Set A contains three designed siRNAs for CER1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24602
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Cer1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cer1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18128
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Cer1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cer1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176568
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LCL768 is a ceramide analog. LCL768 attenuates PARKIN succination to promote PARKIN activation and mitophagy. LCL768 induces CerS1-mediated endogenous C18-ceramide accumulation in mitochondria to mediate mitophagy, which is dependent on DRP1 activation via nitrosylation at C644. LCL768 alters mitochondrial metabolism, resulting in fumarate depletion and leading to tumor suppression. LCL768 improves sensorimotor defects in neurodegenerative diseases like ALS [1] .
Cat. No.: HY-175198
CAS No.: 2928129-57-9
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Cs-2d is a selective ceramide synthases Cer1 inhibitor. Cs-2d has potent inhibitory activity toward C. neoformans Cer1, while maintaining a low off-target effect on human hCerS1. Cs-2d has potent antifungal activity with the significant growth inhibition. Cs-2d can be used for invasive fungal infections research [1].
Cat. No.: HY-179832
CAS No.: 2260670-33-3
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CER1 (d18:1/26:0/18:1) is a ceramide.
Cat. No.: HY-N15835
CAS No.: 917233-21-7
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Cat. No.: HY-120803R
CAS No.: 53780-34-0
Synonyms: MBR 12325 (Standard)
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Mefluidide (Standard) is the analytical standard of Mefluidide. This product is intended for research and analytical applications. Mefluidide is a potent inhibitor of KCS6, CER60 and CER1 enzymes and can be used in herbicide research [1].
Cat. No.: HY-P75350
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Cerberus; DAN domain family member 4; Cer1; DAND4
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Cat. No.: HY-RS02536
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CERS1 Human Pre-designed siRNA Set A contains three designed siRNAs for CERS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19995
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Cers1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cers1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26499
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Cers1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cers1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
